Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Emma Boström"'
Publikováno v:
The Journal of Clinical Pharmacology. 54:1337-1346
Fostamatinib is an oral spleen tyrosine kinase (SYK) inhibitor which has been evaluated as a potential treatment for rheumatoid arthritis (RA). Treatment with fostamatinib has been associated with an increase in blood pressure (BP). In this work, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e0123570bc8da8b9748d80265cfad0b
https://doi.org/10.1002/jcph.341
https://doi.org/10.1002/jcph.341
Autor:
Malin Sydvander, Monica M. Mita, Dung T. Le, James Strauss, Richard Bethell, Siqing Fu, Linda Basse, Russell J. Schilder, Stefan Norin, Mark Albertella, Emma Boström
Publikováno v:
Journal of Clinical Oncology. 37:2506-2506
2506 Background: Birinapant is a bivalent SMAC mimetic targeting cIAP1. Synergistic effects of combining birinapant with immune checkpoint inhibitors have been demonstrated in preclinical models. Based on these observations, a clinical trial with bir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74a29ddb475a5feb8b5eae846f621716
https://doi.org/10.1200/jco.2019.37.15_suppl.2506
https://doi.org/10.1200/jco.2019.37.15_suppl.2506
Publikováno v:
Pharmaceutical Research. 31:489-499
4-[(1S,2S)-2-(4-cyclobutylpiperazine-1-carbonyl)cyclopropyl]benzamide (“AZ1”) is a histamine 3 (H3) autoreceptor in vivo antagonist. Sleep disturbance is a well-known class-effect for H3 antagonists and associated with high H3 receptor occupancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df02ef798e8f9cac669c6cd218dae15
https://doi.org/10.1007/s11095-013-1177-2
https://doi.org/10.1007/s11095-013-1177-2
Autor:
Muhammad Waqas Sadiq, Emma Boström, Margareta Hammarlund-Udenaes, Sven Björkman, Ron J. Keizer
Publikováno v:
Journal of Pharmaceutical Sciences. 102:3320-3331
The aim of this study was to characterize the blood-brain barrier (BBB) transport and pharmacokinetics-pharmacodynamics (PKPD) relationship of oxymorphone and to further elucidate its possible contribution to oxycodone analgesia. The BBB transport of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1931dba4f789b2e1ffe88c978e0b071f
https://doi.org/10.1002/jps.23492
https://doi.org/10.1002/jps.23492
Autor:
John Öhd, Aurelija Jucaite, Emma Boström, Alexandra Potter, Paul A. Newhouse, Pär Karlsson, Björn Paulsson, Kristin Hannesdottir, Judith Jaeger
Publikováno v:
Psychopharmacology. 231:1251-1265
Stimulation of nicotinic cholinergic systems has been shown to alleviate ADHD symptoms and to improve cognitive performance. AZD1446 is a selective α4β2* nicotinic acetylcholine receptor agonist with potential effect on the symptoms of ADHD.The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94dfe5d825971d4a49dd36bdd85d249
https://doi.org/10.1007/s00213-013-3116-7
https://doi.org/10.1007/s00213-013-3116-7
Publikováno v:
Journal of Pharmaceutical Sciences. 97:3433-3441
One of the crucial issues in quantitative microdialysis is the reliability of recovery estimates to correctly estimate unbound drug tissue concentrations. If a deuterated calibrator is used for retrodialysis, the calibrator has the same properties as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d099cd0c38d663e2514cfa39690fe8a
https://doi.org/10.1002/jps.21217
https://doi.org/10.1002/jps.21217
Publikováno v:
Pharmaceutical Research. 23:565-572
The aim of this study was to quantify the olfactory transfer of morphine to the brain hemispheres by comparing brain tissue and plasma morphine levels after nasal administration with those after intravenous administration. Morphine (1.0 mg/kg body we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731f3f7e95295090627ae4b550f2723f
https://doi.org/10.1007/s11095-006-9534-z
https://doi.org/10.1007/s11095-006-9534-z
Publikováno v:
Journal of Pharmaceutical Sciences. 94:1060-1066
The objective of this study was to investigate the in vivo influence of the P-glycoprotein (P-gp) inhibitor PSC833 on the plasma pharmacokinetics, total brain concentrations and tail-flick latency of oxycodone in rats. Eight rats each received an inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3993aa8d0b9cb18997e43fe1d24288ef
https://doi.org/10.1002/jps.20327
https://doi.org/10.1002/jps.20327
Publikováno v:
Rapid Communications in Mass Spectrometry. 18:2565-2576
Sensitive and reproducible methods for the determination of oxycodone, oxymorphone and noroxycodone in Ringer solution, rat plasma and rat brain tissue by liquid chromatography/mass spectrometry are described. Deuterated analogs of the substances wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993d34d67cb1960af9df979b3b754365
https://doi.org/10.1002/rcm.1658
https://doi.org/10.1002/rcm.1658
Autor:
Eija Lummi, Hanna Alanen, Sami Vulli, Kirsi Niinimäki, Eila Anttila, Emma Boström, Sirpa Kinnunen, Aino Gröhn
Publikováno v:
Suomen Maataloustieteellisen Seuran Tiedote
ei saatavilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3e36d3f38df76e888fcdd1024cf3f1
https://journal.fi/smst/article/view/77103
https://journal.fi/smst/article/view/77103