Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Emma Borrego Diaz"'
Autor:
Sushanta K. Banerjee, Peter J. Van Veldhuizen, Emma Borrego-Diaz, Douglas Burns, Saheli Jha, Snigdha Banerjee, Amlan Das, Inamul Haque, Mehmet Tanol, Roger A. Rajewski, Suman Kambhampati
PDF file - 59KB, Rat 2-ME2 and 2-ME2-PD1 dosing summary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9216869575e6ea044be71e3700c86ba
https://doi.org/10.1158/1535-7163.22498728
https://doi.org/10.1158/1535-7163.22498728
Autor:
Sushanta K. Banerjee, Peter J. Van Veldhuizen, Emma Borrego-Diaz, Douglas Burns, Saheli Jha, Snigdha Banerjee, Amlan Das, Inamul Haque, Mehmet Tanol, Roger A. Rajewski, Suman Kambhampati
2-Methoxyestradiol (2-ME2) is an endogenous metabolite of estradiol. In preclinical models, 2-ME2 is effective against different types of tumors. Unfortunately, only low systemic concentrations of 2-ME2 can be achieved following oral administration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b59b8ee75a277902dad405b0ca682a
https://doi.org/10.1158/1535-7163.c.6535956
https://doi.org/10.1158/1535-7163.c.6535956
Autor:
Kun Wang, Vidya Bodempudi, Zhengian Liu, Emma Borrego-Diaz, Farnaz Yamoutpoor, Anna Meyer, Richard A Woo, Weihong Pan, Arkadiusz Z Dudek, Mojtaba S Olyaee, Tuba Esfandyari, Faris Farassati
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33214 (2012)
Mesothelin, a differentiation antigen present in a series of malignancies such as mesothelioma, ovarian, lung and pancreatic cancer, has been studied as a marker for diagnosis and a target for immunotherapy. We, however, were interested in evaluating
Externí odkaz:
https://doaj.org/article/00ea7089c1a64575811513a0a57777f5
Autor:
Kevin F. Ginn, Kyle Kimura, Robyn Gartrell, Daniel Ziazadeh, Ben Fangman, Faris Farassati, Kaoru Terai, Emma Borrego-Diaz, Amanda L. Wise, Kushal J. Shah, Brandon Ricke, Sharad C. Mathur
Publikováno v:
Journal of Neuro-Oncology. 130:99-110
Medulloblastoma (MDB) represents a major form of malignant brain tumors in the pediatric population. A vast spectrum of research on MDB has advanced our understanding of the underlying mechanism, however, a significant need still exists to develop no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6de05ce3fb829b368e93febc05bce71
https://doi.org/10.1007/s11060-016-2236-4
https://doi.org/10.1007/s11060-016-2236-4
Autor:
Faris Farassati, Atabak Asvadi Kermani, Elham Patrad, Mohammad Taha, Kun Wang, Bashar Abdulkarim, Kristina Lialyte, Mina Soleimani, Tuba Esfandyari, Emma Borrego-Diaz, Amanda L. Wise, Mohamad Ezzeldin, Stephen K. Williamson, Alex Rouyanian, Mojtaba Olyaee, Warner Peng
Publikováno v:
Molecular Oncology. 8:1043-1053
Ral (Ras like) leads an important proto‐oncogenic signaling pathway down‐stream of Ras. In this work, RalA was found to be significantly overactivated in hepatocellular carcinoma (HCC) cells and tissues as compared to non‐malignant samples. Oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d5c9ecbfdb8b53249cf1e0b42494dd
https://doi.org/10.1016/j.molonc.2014.03.020
https://doi.org/10.1016/j.molonc.2014.03.020
Autor:
Emma Borrego-Diaz Reyes, Chao H. Huang, Andrew K. Godwin, Hannah Motes, Inamul Haque, Mukut Sharma
Publikováno v:
Cancer Research. 78:485-485
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are now standard of care in lung cancer patients with EGFR mutation. Invariably, these patients develop resistance and require treatment with another EGFR-TKI or chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbab4465e863686c8eb29d4da15575c0
https://doi.org/10.1158/1538-7445.am2018-485
https://doi.org/10.1158/1538-7445.am2018-485
Autor:
Joseph M. Chalovich, Emma Borrego-Diaz
Publikováno v:
Biophysical Journal. 98:2601-2609
Changes in the muscle regulatory protein complex, troponin, are important for modulation of activity and may occur as a result of disease-causing mutations. Both increases and decreases in the rate of ATP hydrolysis by myosin may occur as dictated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381fdda94f479dee41033fce805d2a61
https://doi.org/10.1016/j.bpj.2010.02.030
https://doi.org/10.1016/j.bpj.2010.02.030
Publikováno v:
Cancer Research. 77:1481-1481
Background: Cellular microRNAs (miRNAs) regulate gene expression through modulation of messenger RNA transcription and are involved in epigenetic regulation, metastasis and cancer immunity. They have prognostic and therapeutic significance. The miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2090cc9ce46cf39b4116dbafd6cd6d59
https://doi.org/10.1158/1538-7445.am2017-1481
https://doi.org/10.1158/1538-7445.am2017-1481
Publikováno v:
Journal of Biological Chemistry. 274:29483-29492
The inositol 1,4,5-trisphosphate receptor (InsP3R) is a tetrameric assembly of highly conserved subunits that contain multiple membrane-spanning sequences in the C-terminal region of the protein. In studies aimed at investigating the oligomerization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30100125c1f655c11f79fe5af45e3c2
https://doi.org/10.1074/jbc.274.41.29483
https://doi.org/10.1074/jbc.274.41.29483
Autor:
Kaoru Terai, Tuba Esfandyari, Warner Peng, Darren Lovick, Roya Dolatkhah, Faris Farassati, Elham Patrad, Mojtaba Amani, Adel Rezaei Moghadam, Michael Salacz, Zohreh Sanaat, Emma Borrego-Diaz
Publikováno v:
Neuro-Oncology. 17:iii35-iii36
For the last 20 years, cellular biologists have been focusing on the role of Ras signaling pathway in neurofibromatosis 1(NF1) and its lethal derivation, malignant peripheral nerve sheath tumors (MPNST). While our team has worked on the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303490daee7488bc4be72c81c5379517
https://doi.org/10.1093/neuonc/nov061.143
https://doi.org/10.1093/neuonc/nov061.143