Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Emma Blackham"'
Autor:
Andrew Novak, David Laughton, Rebecca Lane, Emma Blackham, Jennifer Thomas, Elli Chatzopoulou, Joseph Wrigglesworth, Abdul Quddus, Saleh Ahmed, David Cousin, Lorna Duffy, Nathalie Dubois, John Unitt, Katalin Orban, Edward Browne, Michelle Ward, David Mycock, Maria Ieva, Nicholas Bland, Pascal George, Timothy Bourne, Hélène Asnagli, Louise Birch, Geraint Jones
Publikováno v:
Journal of Medicinal Chemistry. 65:16640-16650
Herein, we report the discovery of a first-in-class chemotype 2-(alkylsulfonamido)thiazol-4-yl)acetamides that act as pan-selective inhibitors of cytidine 5'-triphosphate synthetase (CTPS1/2), critical enzymes in the
Autor:
Gupte, Sachin A.1 (AUTHOR) s_gupte@nymc.edu, Bakshi, Chandra Shekhar2 (AUTHOR), Blackham, Emma3 (AUTHOR), Duhamel, Gerald E.4 (AUTHOR), Jordan, Allan3 (AUTHOR), Salgame, Padmini5 (AUTHOR), D'silva, Melinee1 (AUTHOR), Khan, Mohammad Y.1 (AUTHOR), Nadler, Jerry1,6 (AUTHOR), Gupte, Rakhee1 (AUTHOR)
Publikováno v:
British Journal of Pharmacology. Oct2023, Vol. 180 Issue 20, p2677-2693. 17p. 3 Color Photographs, 1 Chart, 6 Graphs.