Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emma B. Brandt"'
Autor:
Saji Oommen, Susana Cantero Peral, Muhammad Y. Qureshi, Kimberly A. Holst, Harold M. Burkhart, Matthew A. Hathcock, Walter K. Kremers, Emma B. Brandt, Brandon T. Larsen, Joseph A. Dearani, Brooks S. Edwards, Joseph J. Maleszewski, Timothy J. Nelson
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Congenital heart diseases, including single ventricle circulations, are clinically challenging due to chronic pressure overload and the inability of the myocardium to compensate for lifelong physiological demands. To determine the clinical relevance
Externí odkaz:
https://doaj.org/article/0ad959fde7064b8dba196e59cae044b6
Publikováno v:
Bioelectronic Medicine, Vol 5, Iss 1, Pp 1-8 (2019)
Abstract Ischemic heart disease is the leading cause of death worldwide. The blockade of coronary arteries limits oxygen-rich blood to the heart and consequently there is cardiomyocyte (CM) cell death, inflammation, fibrotic scarring, and myocardial
Externí odkaz:
https://doaj.org/article/024758b91fc44b8b91b8b1a7dacb73a1
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20948-20967 (2014)
Stem cells harbor significant potential for regenerative medicine as well as basic and clinical translational research. Prior to harnessing their reparative nature for degenerative diseases, concerns regarding their genetic integrity and mutation acq
Externí odkaz:
https://doaj.org/article/e1a406b9884a4ad8917b3711774b840d
Autor:
Emma B, Brandt, Ahmed I, Mahmoud
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2485
Neonatal mice display a remarkable ability to regenerate their heart following an injury during the first week of life. A key facet of successful cardiac regeneration is the proliferation of cardiomyocytes to replace the lost cells. Stimulating cardi
Autor:
Emma B. Brandt, Ahmed I. Mahmoud
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edaf9e616db064d6389441daedcc8a6
https://doi.org/10.1007/978-1-0716-2261-2_16
https://doi.org/10.1007/978-1-0716-2261-2_16
Publikováno v:
J Stem Cell Rep
Activation of the transcription factor P53 within cancer cells is a well-characterized pathway, whereas the effects of P53 activation during development remain largely unexplored. Previous research has indicated that increased levels of P53 protein d
Autor:
Sherri M. Biendarra-Tiegs, Emma B. Brandt, Xing Li, Michael J. Ackerman, Timothy J. Nelson, Dan Ye
Publikováno v:
Stem Cells and Development
The ability to accurately phenotype cells differentiated from human induced pluripotent stem cells (hiPSCs) is essential for their application in modeling developmental and disease processes, yet also poses a particular challenge without the context
Autor:
Rebecca J. Salamon, Jiyoung Bae, Wyatt G. Paltzer, Emma B. Brandt, Jing Fan, Ziheng Zhang, Timothy A. Hacker, Emily C. Britt, Ahmed I. Mahmoud
Publikováno v:
Circulation. 143(20)
Background: Neonatal mouse cardiomyocytes undergo a metabolic switch from glycolysis to oxidative phosphorylation, which results in a significant increase in reactive oxygen species production that induces DNA damage. These cellular changes contribut
Autor:
Timothy J. Nelson, Frank J. Secreto, Alyson J. Smith, Bonnie K. Arendt, Sybil C. L. Hrstka, Ester Perales-Clemente, Emma B. Brandt, Elizabeth S. Bruinsma, Xing Li, Gresin Hawse, Saji Oommen, Dennis A. Wigle
Publikováno v:
Stem Cells Translational Medicine
Human induced pluripotent stem cells (hiPSC) hold great promise in diagnostic and therapeutic applications. However, translation of hiPSC technology depends upon a means of assessing hiPSC quality that is quantitative, high-throughput, and can deciph
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20948-20967 (2014)
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20948-20967 (2014)
Stem cells harbor significant potential for regenerative medicine as well as basic and clinical translational research. Prior to harnessing their reparative nature for degenerative diseases, concerns regarding their genetic integrity and mutation acq