Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Emma Adhikari"'
Autor:
Qian Liu, Emma Adhikari, Daniel K. Lester, Bin Fang, Joseph O. Johnson, Yijun Tian, Andrea T. Mockabee-Macias, Victoria Izumi, Kelly M. Guzman, Michael G. White, John M. Koomen, Jennifer A. Wargo, Jane L. Messina, Jianfei Qi, Eric K. Lau
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Melanoma incidence and mortality rates are historically higher for men than women. Although emerging studies have highlighted tumorigenic roles for the male sex hormone androgen and its receptor (AR) in melanoma, cellular and molecular mecha
Externí odkaz:
https://doaj.org/article/1d6b5538888248d5b44646f3fe07e1be
Autor:
Emma Adhikari, Qian Liu, Joseph Johnson, Paul Stewart, Viktoriya Marusyk, Bin Fang, Victoria Izumi, Kiah Bowers, Kelly M. Guzman, John M. Koomen, Andriy Marusyk, Eric K. Lau
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113463- (2023)
Summary: Brain metastasis cancer-associated fibroblasts (bmCAFs) are emerging as crucial players in the development of breast cancer brain metastasis (BCBM), but our understanding of the underlying molecular mechanisms is limited. In this study, we a
Externí odkaz:
https://doaj.org/article/c94698fc17e54b619ec84e1ff20702ab
Autor:
Didem Ilter, Stanislav Drapela, Tanya Schild, Nathan P. Ward, Emma Adhikari, Vivien Low, John Asara, Thordur Oskarsson, Eric K. Lau, Gina M. DeNicola, Melanie R. McReynolds, Ana P. Gomes
Publikováno v:
Redox Biology, Vol 61, Iss , Pp 102627- (2023)
Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. NAD
Externí odkaz:
https://doaj.org/article/e2c33671c9844c32a8eea52be1ef6e6d
Autor:
Daniel K. Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B. Williamson, Dennie T. Frederick, Tatyana Sharova, Michael G. White, Joseph Markowitz, Biwei Cao, Jonathan Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei-Ling Chen, Susan McCarthy, Carlos MoranSegura, Jane Messina, Kerry L. Thomas, Lancia Darville, Victoria Izumi, John M. Koomen, Shari A. Pilon-Thomas, Brian Ruffell, Vincent C. Luca, Robert S. Haltiwanger, Xuefeng Wang, Jennifer A. Wargo, Genevieve M. Boland, Eric K. Lau
Publikováno v:
Nature Cancer. 4:222-239
Despite reports of striking outcomes, immunotherapy efficacy in melanoma is limited to subsets of patients 1, 2. Combining immunotherapies with other modalities has yielded limited improvements but also adverse events requiring cessation of treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a64da195ce606f3ff385fc17153f645
https://doi.org/10.1038/s43018-022-00506-7
https://doi.org/10.1038/s43018-022-00506-7
Autor:
Eric B. Haura, John M. Koomen, Aaron S. Meyer, Theresa A. Boyle, Eric A. Welsh, Paul A. Stewart, Bin Fang, Kiah Bowers, Fumi Kinose, Benjamin S. Meyer, Marc Creixell, Shruti Agarwal, Guolin Zhang, Matthew A. Smith, James J. Saller, Emma Adhikari, Mia Stroud, Sina Hosseinian, Anurima Majumder
Supplementary Figure from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ac75589010fb268fb647b52f21f8ac
https://doi.org/10.1158/1541-7786.22527645
https://doi.org/10.1158/1541-7786.22527645
Autor:
Eric B. Haura, John M. Koomen, Aaron S. Meyer, Theresa A. Boyle, Eric A. Welsh, Paul A. Stewart, Bin Fang, Kiah Bowers, Fumi Kinose, Benjamin S. Meyer, Marc Creixell, Shruti Agarwal, Guolin Zhang, Matthew A. Smith, James J. Saller, Emma Adhikari, Mia Stroud, Sina Hosseinian, Anurima Majumder
Supplementary Table from Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b116c1823d2cbb8b239010da1bf43a
https://doi.org/10.1158/1541-7786.22527618.v1
https://doi.org/10.1158/1541-7786.22527618.v1
Autor:
Qian Liu, Emma Adhikari, Daniel Lester, Bin Fang, Joseph Johnson, Yijun Tian, Andrea Mockabee-Macias, Vicky Izumi, Kelly Guzman, Michael White, John Koomen, Jennifer Wargo, Jane Messina, Jianfei Qi, Eric Lau
Melanoma incidence and mortality rates are historically higher for men than women. Although emerging studies have highlighted tumorigenic roles for the male sex hormone androgen and its receptor (AR) in melanoma, cellular and molecular mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb70baba2b1db02ec7a7a889845a356
https://doi.org/10.21203/rs.3.rs-2623307/v1
https://doi.org/10.21203/rs.3.rs-2623307/v1
Autor:
Anurima Majumder, Sina Hosseinian, Mia Stroud, Emma Adhikari, James J. Saller, Matthew A. Smith, Guolin Zhang, Shruti Agarwal, Marc Creixell, Benjamin S. Meyer, Fumi Kinose, Kiah Bowers, Bin Fang, Paul A. Stewart, Eric A. Welsh, Theresa A. Boyle, Aaron S. Meyer, John M. Koomen, Eric B. Haura
Publikováno v:
Molecular cancer research : MCR, vol 20, iss 4
Mol Cancer Res
Mol Cancer Res
To better understand the signaling complexity of AXL, a member of the tumor-associated macrophage (TAM) receptor tyrosine kinase family, we created a physical and functional map of AXL signaling interactions, phosphorylation events, and target-engage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd271e9f60159ea5ac568170e860c7ba
https://escholarship.org/uc/item/4gt10245
https://escholarship.org/uc/item/4gt10245
Autor:
Didem Ilter, Tanya Schild, Nathan P. Ward, Stanislav Drapela, Emma Adhikari, Vivien Low, Eric Le-Lau, Gina M. DeNicola, Melanie R. McReynolds, Ana P. Gomes
Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism to adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. Cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae375661c9b3cc6671efd973e6335634
https://doi.org/10.1101/2022.03.25.485887
https://doi.org/10.1101/2022.03.25.485887
Autor:
Shikha Mahajan, Anurima Majumder, Paul A. Stewart, Yian Ann Chen, Emma Adhikari, Bin Fang, Yan Yang, Harshani Lawrence, Fumi Kinose, John M. Koomen, Eric B. Haura
Publikováno v:
ACS chemical biology. 17(4)
To aid in the prioritization of deubiquitinases (DUBs) as anticancer targets, we developed an approach combining activity-based protein profiling (ABPP) with mass spectrometry in both non-small cell lung cancer (NSCLC) tumor tissues and cell lines al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622d3bc6c624920586091ee4c67f7948
https://pubmed.ncbi.nlm.nih.gov/35311290
https://pubmed.ncbi.nlm.nih.gov/35311290