Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emma, Svedin"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103874 (2014)
Impairment in beta-cell exocytosis is associated with reduced insulin secretion and diabetes. Here we aimed to investigate the dynamics of Ca2+-dependent insulin exocytosis with respect to pool depletion and Ca2+-current inactivation. We studied exoc
Externí odkaz:
https://doaj.org/article/e9f650f19807421a8635c77131ee7812
Autor:
Sebastian Kapell, Pär G. Larsson, Emma Svedin, Olli H. Laitinen, Erna Domsgen, Virginia M. Stone, Minna M. Hankaniemi, Malin Flodström-Tullberg, Juha A. E. Määttä, Vesa P. Hytönen, Heikki Hyöty
Publikováno v:
Journal of Virological Methods. 255:29-37
Enteroviruses (EVs), such as the Coxsackie B-viruses (CVBs), are common human pathogens, which can cause severe diseases including meningitis, myocarditis and neonatal sepsis. EVs encode two proteases (2Apro and 3Cpro), which perform the proteolytic
Autor:
Sami Oikarinen, Malin Flodström-Tullberg, Amir-Babak Sioofy-Khojine, Emma Svedin, Olli H. Laitinen, Vesa P. Hytönen, Virginia M. Stone, Heikki Hyöty, Minna M. Hankaniemi
Publikováno v:
Diabetologia
Aims/hypothesis Epidemiological studies suggest a role for Coxsackievirus B (CVB) serotypes in the pathogenesis of type 1 diabetes, but their actual contribution remains elusive. In the present study, we have produced a CVB1 vaccine to test whether v
Autor:
Inês G. Mollet, Bob J. Scholte, Nils Wierup, Michael Huhn, Lena Eliasson, Emma Svedin, Anna Wendt, Anna Edlund, Enming Zhang, Jonathan L.S. Esguerra, Erik Renström, Malin Flodström-Tullberg, Mia Abels, Mohammad Barghouth
Publikováno v:
Journal of Endocrinology, 241(1), 45-57. Bioscientifica Ltd
Cystic fibrosis-related diabetes (CFRD) is a common complication for patients with cystic fibrosis (CF), a disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). The cause of CFRD is unclear, but a commonly obs
Autor:
Markus Moll, Katharina Lind, Olli H. Laitinen, Sebastian Kapell, Malin Flodström-Tullberg, Erna Domsgen, Emma Svedin
Publikováno v:
Journal of General Virology. 97:1368-1380
Type I IFNs play an important role in the immune response to enterovirus infections. Their importance is underscored by observations showing that many enteroviruses including coxsackie B viruses (CVBs) have developed strategies to block type I IFN pr
Autor:
Olli H, Laitinen, Emma, Svedin, Sebastian, Kapell, Minna M, Hankaniemi, Pär G, Larsson, Erna, Domsgen, Virginia M, Stone, Juha A E, Määttä, Heikki, Hyöty, Vesa P, Hytönen, Malin, Flodström-Tullberg
Publikováno v:
Journal of virological methods. 255
Enteroviruses (EVs), such as the Coxsackie B-viruses (CVBs), are common human pathogens, which can cause severe diseases including meningitis, myocarditis and neonatal sepsis. EVs encode two proteases (2A
Publikováno v:
Acta Paediatrica. 105:851-853
Publikováno v:
Clinical and Experimental Immunology. 177:687-695
Summary Hepatitis is a common and potentially fatal manifestation of severe Coxsackievirus infections, particularly in newborn children. Little is known of the immune-mediated mechanisms regulating permissiveness to liver infection. It is well establ
Autor:
Maho Nagasawa, Jakob Michaëlsson, Jonas S. Erjefält, Adrian Carlsson, Ulrik Lindforss, Danielle Friberg, Niklas K. Björkström, Lena Berglin, Malin Flodström-Tullberg, Marianne Forkel, Eliisa Kekäläinen, Annika Bergquist, Hans-Gustaf Ljunggren, Jenny Mjösberg, Emma Svedin, Michiko Mori, Magnus Westgren, Carl Jorns, Ewa Ellis
Publikováno v:
European journal of immunology, 47(8), 1280-1294. Wiley-VCH Verlag
Human innate lymphoid cells have been described to exist in different organs, with functional deregulation of these cells contributing to several disease states. Here, we performed the first detailed characterization of the phenotype, tissue-residenc
Autor:
Pia Leete, Alan K. Foulis, Maarit Oikarinen, Therese Rosenling, Sarah J. Richardson, Adrian J. Bone, Shalinee Dhayal, Katharina Lind, Mark Russell, Gun Frisk, Noel G. Morgan, Malin Flodström-Tullberg, Jutta E. Laiho, Heikki Hyöty, Didier Hober, Emma Svedin, Nora M. Chapman
Publikováno v:
Diabetologia; Vol 57
Enteroviral infection has been implicated in the development of islet autoimmunity in type 1 diabetes and enteroviral antigen expression has been detected by immunohistochemistry in the pancreatic beta cells of patients with recent-onset type 1 diabe