Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Emma, Assi"'
Autor:
Francesca D’Addio, Emma Assi, Anna Maestroni, Giada Rossi, Vera Usuelli, Adriana Petrazzuolo, Marta Nardini, Cristian Loretelli, Moufida Ben Nasr, Paolo Fiorina
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Pancreatic beta cells replenishment is considered the next therapeutic option for type 1 diabetes; while stimulating endogenous beta cells proliferation is the “holy grail” for those patients with exhausted beta cell mass. Here we are demonstrati
Externí odkaz:
https://doaj.org/article/3c19f5f129a14d3dadfdbfbfd1eeb6c7
Autor:
Cristian Loretelli, Ida Pastore, Maria Elena Lunati, Ahmed Abdelsalam, Vera Usuelli, Emma Assi, Emma Fiorina, Lara Loreggian, Hari Baskar Balasubramanian, Yanan Xie, Jun Yang, Basset El Essawy, Laura Montefusco, Francesca D’Addio, Moufida Ben Nasr, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106709- (2023)
Purpose of review: The purine nucleotide adenosine triphosphate (ATP) is released into extracellular spaces as extracellular ATP (eATP) as a consequence of cell injury or death and activates the purinergic receptors. Once released, eATP may facilitat
Externí odkaz:
https://doaj.org/article/5c2281d1b2b142519e43165a1710f8a3
Autor:
Adriana Petrazzuolo, Gianmarco Sabiu, Emma Assi, Anna Maestroni, Ida Pastore, Maria Elena Lunati, Laura Montefusco, Cristian Loretelli, Giada Rossi, Moufida Ben Nasr, Vera Usuelli, Yanan Xie, Hari Baskar Balasubramanian, Monica Zocchi, Basset El Essawy, Jun Yang, Francesca D’Addio, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106710- (2023)
Diabetic kidney disease (DKD) is the first cause of end-stage kidney disease in patients with diabetes and its prevalence is increasing worldwide. It encompasses histological alterations that mainly affect the glomerular filtration unit, which includ
Externí odkaz:
https://doaj.org/article/f4d913eb8c7b477ba0c24bf7919d6299
Autor:
Francesca D’Addio, Anna Maestroni, Emma Assi, Moufida Ben Nasr, Giovanni Amabile, Vera Usuelli, Cristian Loretelli, Federico Bertuzzi, Barbara Antonioli, Francesco Cardarelli, Basset El Essawy, Anna Solini, Ivan C. Gerling, Cristina Bianchi, Gabriella Becchi, Serena Mazzucchelli, Domenico Corradi, Gian Paolo Fadini, Diego Foschi, James F. Markmann, Emanuela Orsi, Jan Škrha, Maria Gabriella Camboni, Reza Abdi, A. M. James Shapiro, Franco Folli, Johnny Ludvigsson, Stefano Del Prato, Gianvincenzo Zuccotti, Paolo Fiorina
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this new study the Authors demonstrated that the IGFBP3/TMEM219 pathway is a physiological regulator of pancreatic beta cell homeostasis and it is dysregulated in diabetes. IGFBP3/TMEM219 targeting may therefore serve as a therapeutic option in di
Externí odkaz:
https://doaj.org/article/691fd79ad7294c7890d97254a673270c
Autor:
Carla Perego, Eliana S. Di Cairano, Alessandra Galli, Stefania Moretti, Elena Bazzigaluppi, Victoria Frolich Centonze, Amalia Gastaldelli, Emma Assi, Paolo Fiorina, Massimo Federici, Ottavia Porzio, Federico Bertuzzi, Alberto M. Davalli, Franco Folli
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106130- (2022)
Islet cell surface autoantibodies were previously found in subjects with type 1 diabetes mellitus (T1DM), but their target antigens and pathogenic mechanisms remain elusive. The glutamate transporter solute carrier family 1, member 2 (GLT1/EAAT2) is
Externí odkaz:
https://doaj.org/article/380a126dc7ac46df9a35236c18b92a58
Autor:
Cristian Loretelli, Ahmed Abdelsalam, Francesca D’Addio, Moufida Ben Nasr, Emma Assi, Vera Usuelli, Anna Maestroni, Andy Joe Seelam, Elio Ippolito, Stefania Di Maggio, Lara Loreggian, Dejan Radovanovic, Claudia Vanetti, Jun Yang, Basset El Essawy, Antonio Rossi, Ida Pastore, Laura Montefusco, Maria Elena Lunati, Andrea M. Bolla, Mara Biasin, Spinello Antinori, Pierachille Santus, Agostino Riva, Gian Vincenzo Zuccotti, Massimo Galli, Stefano Rusconi, Paolo Fiorina
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
A substantial proportion of patients who have recovered from coronavirus disease-2019 (COVID-19) experience COVID-19–related symptoms even months after hospital discharge. We extensively immunologically characterized patients who recovered from COV
Externí odkaz:
https://doaj.org/article/d677986fcd484bfc91c312a6c5663b31
Autor:
Ida Pastore, Emma Assi, Moufida Ben Nasr, Andrea Mario Bolla, Anna Maestroni, Vera Usuelli, Cristian Loretelli, Andy Joe Seelam, Ahmed Abdelsalam, Gian Vincenzo Zuccotti, Francesca D’Addio, Paolo Fiorina
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite the increasing knowledge of pathophysiological mechanisms underlying the onset of type 1 diabetes (T1D), the quest for therapeutic options capable of delaying/reverting the diseases is still ongoing. Among all strategies currently tested in T
Externí odkaz:
https://doaj.org/article/09f67fa8c46c4196838e948fc508bc7c
Autor:
Michele Reni, Valentina Andreasi, Anna Maria Gasparri, Erica Dugnani, Barbara Colombo, Marina Macchini, Mimma Bianco, Alice Dallatomasina, Antonio Citro, Emma Assi, Maria Pia Protti, Antonio Esposito, Massimo Falconi, Flavio Curnis, Lorenzo Piemonti, Angelo Corti
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Chromogranin A (CgA), a secretory protein released in the blood by the neuroendocrine system, consists of a mixture of full-length molecules and fragments endowed of vasoregulatory activity. The extent and the role of CgA fragmentation were investiga
Externí odkaz:
https://doaj.org/article/e241b3a63c694aae99237b1b10df6666
Autor:
Irene Cetin, Emma Assi, Francesca D'Addio, Chiara Mandò, Anna Maestroni, Cristian Loretelli, Moufida Ben Nasr, Vera Usuelli, Ahmed Abdelsalam, Andy Joe Seelam, Ida Pastore, Cinzia Magagnotti, Reza Abdi, Basset El Essawy, Franco Folli, Domenico Corradi, Gianvincenzo Zuccotti, Paolo Fiorina
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 2 (2020)
Introduction Gestational diabetes mellitus (GDM) is the most frequent metabolic complication during pregnancy and is associated with development of short-term and long-term complications for newborns, with large-for-gestational-age (LGA) being partic
Externí odkaz:
https://doaj.org/article/57b6bc61b0354fbdbf7c611824966d41
Autor:
Francesca D'Addio, Laura Montefusco, Maria Elena Lunati, Ida Pastore, Emma Assi, Adriana Petrazzuolo, Virna Marin, Chiara Bruckmann, Paolo Fiorina
Publikováno v:
BioEssays. 45