Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eminy H Y Lee"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283908 (2023)
Long-term memory formation requires de novo RNA and protein synthesis. By using the differential display-polymerase chain reaction strategy, we have presently identified the Nedd4 family interacting protein 1 (Ndfip1) cDNA fragment that is differenti
Externí odkaz:
https://doaj.org/article/ff08ed027d5044c3b6a9bae53f24bdb8
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-20 (2017)
Abstract Background Smad4 is a critical effector of TGF-β signaling that regulates a variety of cellular functions. However, its role in the brain has rarely been studied. Here, we examined the molecular mechanisms underlying the post-translational
Externí odkaz:
https://doaj.org/article/b2ba92ad622f4202ae49e5b55af82f26
Autor:
Derek J. C. Tai, Yen C. Liu, Wei L. Hsu, Yun L. Ma, Sin J. Cheng, Shau Y. Liu, Eminy H. Y. Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Post-translational modifications of methyl-CpG-binding protein 2 (MeCP2) are important for its function and dysfunction in Rett syndrome. Here, Tai et al. show a functional interaction between MeCP2 SUMOylation and phosphorylation in rodent behavior
Externí odkaz:
https://doaj.org/article/12ecdd0778e649b788738dc5fc934974
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Galectin-3, a member of the galectin protein family, has been found to regulate cell proliferation, inhibit apoptosis and promote inflammatory responses. Galectin-3 is also expressed in the adult rat hippocampus, but its role in learning and memory f
Externí odkaz:
https://doaj.org/article/2b23373bc0924e8d82b818e52f3e74a8
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Protein inhibitor of activated STAT1 (PIAS1) is phosphorylated by IKKα at Ser(90) in a PIAS1 E3 ligase activity‐dependent manner. Whether PIAS1 is also phosphorylated at other residues and the functional significance of the
Publikováno v:
Brain Pathol
Brain‐derived neurotrophic factor (BDNF) was shown to produce its neuroprotective effect through extracellular signal‐regulated kinase 1/2 (ERK1/2) and phosphatidylinositol‐3 kinase (PI3‐K) signaling. But whether other pathways also mediate t
Publikováno v:
The EMBO journal. 30(1)
By using differential display PCR, we have previously identified 98 cDNA fragments from rat dorsal hippocampus, which are expressed differentially between the fast learners and slow learners from water-maze learning task. One cDNA fragment, which sho
Publikováno v:
NeuroReport. 3:777-780
The present study examined the effects of deprenyl (1.5 mg kg-1) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (30 mg kg-1) on dopamine (DA), norepinephrine (NE) and motor activity in BALB/c mice. Results indicate that pre-treatment with de
Publikováno v:
Neuroreport. 3(2)
This study examines the roles of PKC and protein phosphorylation in the retention performance of a passive avoidance learning (PAL) task in rats. Results revealed that H7 injected into the dentate gyrus (DG) of the hippocampus impaired retention in a