Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Emina, Vorkapic"'
Autor:
Emina Vorkapic, Maggie Folkesson, Kerstin Magnell, Mohammad Bohlooly-Y, Toste Länne, Dick Wågsäter
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178729 (2017)
Extracellular matrix degradation is a hallmark of abdominal aortic aneurysm (AAA). Among proteases that are capable of degrading extracellular matrix are a disintegrin and metalloproteases with thrombospondin motifs (ADAMTS). Pathogenesis of these pr
Externí odkaz:
https://doaj.org/article/0a50547889e14186804afd6b2eb49354
Autor:
Jan Dimberg, Martin Welander, Emina Vorkapic, Toste Länne, Josefin Skogberg, Maggie Folkesson, Dick Wågsäter, Marike Gabrielson, Andreas Matussek
Publikováno v:
Journal of Vascular Research. 53:17-26
Introduction: Abdominal aortic aneurysm (AAA) is a complex and deadly vascular disorder. The pathogenesis of AAA includes destruction and phenotypic alterations of the vascular smooth muscle cells (VSMCs) and aortic tissues. PPARγ coactivator-1 alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf820e1ddc19a31d637384f9addf447
https://doi.org/10.1159/000446653
https://doi.org/10.1159/000446653
Autor:
Hong Jin, Lars Maegdefessel, Ana Carolina Araújo, Dick Wågsäter, Emina Vorkapic, Antonio Di Gennaro, Per Eriksson, Albert Busch, Jesper Z. Haeggström, Kenneth Caidahl, Bengt Samuelsson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Significance Cysteinyl-leukotrienes (cys-LTs) are lipid mediators involved in human inflammatory diseases, in particular asthma. We have previously identified cys-LTs in tissue specimens of human abdominal aortic aneurysm (AAA) and linked these media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14953cfbe4ab8f30431435488df85c8
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-145761
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-145761
Autor:
Dick Wågsäter, Bruno Igreja, Nuno Pires, Anders Hamsten, Emina Vorkapic, Laura Brion, Alejandro M. Bertorello, Margareta Behrendt, Johannes Wikström, Per Eriksson, Maria João Pinho, Patrício Soares-da-Silva
Publikováno v:
Circulation Research. 116:642-652
Rationale: In human genetic studies a single nucleotide polymorphism within the salt-inducible kinase 1 ( SIK1 ) gene was associated with hypertension. Lower SIK1 activity in vascular smooth muscle cells (VSMCs) leads to decreased sodium-potassium AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67676931c33ac90112681875de1df532
https://doi.org/10.1161/circresaha.116.304529
https://doi.org/10.1161/circresaha.116.304529
Publikováno v:
Molecular Medicine Reports
Osteoprotegerin (OPG), additionally termed tumor necrosis factor receptor superfamily member 11B, is produced by vascular smooth muscle cells (VSMCs) and endothelial cells in the vasculature, and its release may be modulated by pro-inflammatory cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194ad0f778f215b27dbf3185e795f4f6
https://pubmed.ncbi.nlm.nih.gov/29749489
https://pubmed.ncbi.nlm.nih.gov/29749489
Autor:
Toste Länne, Rachel De Basso, Emina Vorkapic, Dick Wågsäter, Martin Björck, Anders Wanhainen, Kevin Mani
Background and aims MicroRNA (miR) are important regulators of gene expression and biological processes and have recently been suggested as possible biomarkers for abdominal aortic aneurysm (AAA) disease. The aim of the present study was to assess th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0139e17b39a9a593b7b82ecfb81f19f
http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-34761
http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-34761
Autor:
Per Eriksson, Mikko I. Mäyränpää, Dick Wågsäter, Emina Vorkapic, Joy Roy, Elma Dugic, Svante Vikingsson
Background: Abdominal aortic aneurysm (AAA) is characterized by vascular remodeling with increased infiltration of inflammatory cells and apoptosis/modulation of vascular smooth muscle cells (SMCs). Imatinib is a selective inhibitor of several tyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6610e08d8bd64c2b541fa4c0dea66e8c
http://hdl.handle.net/10138/224038
http://hdl.handle.net/10138/224038
Autor:
Emina Vorkapic
Publikováno v:
Targeting vascular remodeling in abdominal aortic aneurysm : To identify novel treatment strategies and drug candidates
Abdominal aortic aneurysm (AAA) is a degenerative weakening of the aortic wall, mainly affecting elderly men with a prevalence of 4.4-7.7 %. AAA is characterized by medial and adventitial inflammat ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37aacc043bbe66b03478d2b0020b4416
https://doi.org/10.3384/diss.diva-127502
https://doi.org/10.3384/diss.diva-127502
Autor:
Dick Wågsäter, Emina Vorkapic, Martin Welander, Burkhard Kleuser, Maggie Folkesson, Lukasz Japtok, Erich Gulbins, Toste Länne
BackgroundAbdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains poorly understood. Investigation into the physical and molecular characteristics of perivascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc87d92e09989916ffeb254bc1938f86
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/55103
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/55103
Autor:
Emina Vorkapic, Aldons J. Lusis, Jason K. Kim, Caroline M. W. van Stijn, Dick Wågsäter, Per Eriksson, Rajendra K. Tangirala
Publikováno v:
Scientific Reports
Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by aortic dilation and rupture leading to sudden death. Currently, no non-surgical treatments are available and novel therapeutic targets are needed to prevent AAA. We investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c8e32cd14137a23b4be8fde9b3541c
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132053
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132053