Zobrazeno 1 - 10
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pro vyhledávání: '"Emin Saripinar"'
Publikováno v:
Proceedings, Vol 1, Iss 10, p 1008 (2017)
Aminoguanidine (AG) was presented more than 100 years ago. During the last 30 years important effects of AG have been discovered which have made this molecule attract a lot of interest. AG has anticancer effect on gastric cancer, and it has positive
Externí odkaz:
https://doaj.org/article/b37baf393ffe400b892a50251354ebfb
Autor:
Nuriye Doğan, Sevtap Çağlar Yavuz, Kader Sahin, Muge Didem Orhan, Hüseyin Kekeçmuhammed, Seyma Calis, Fatma Öztürk Küp, Timucin Avsar, Senem Akkoc, Michael Tapera, Onur Sahin, Turker Kilic, Serdar Durdagi, Emin Saripinar
© 2022 Wiley-VCH GmbH.In recent years, various compounds including the aminoguanidine scaffold have been reported to exhibit diverse biological activities. In the current study, 16 compounds that include guanylhydrazone (aminoguanidine) moiety (3 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2583ba4618e33738474731322a6d88
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/97732
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/97732
Publikováno v:
Journal of Heterocyclic Chemistry. 57:2615-2627
In a single reaction step, pyrimidine derivatives (4a-p) were synthesized from the triple reaction of aromatic aldehydes (1), ethyl cyanoacetate (2), and some guanyl hydrazone derivatives (3a-n). These compounds were tested as in vitro against two ty
Autor:
Emin Saripinar, Kader Sahin
Publikováno v:
Journal of Computational Chemistry. 41:1091-1104
To understand the structure-activity correlation of a group of tetrahydrodibenzazocines as inhibitors of 17β-hydroxysteroid dehydrogenase type 3, we have performed a combined genetic algorithm (GA) and four-dimensional quantitative structure-activit
Synthesis and Single Crystal X-Ray Structure of 3,5-Diphenyl-1-(phenylacetyl)-4,5-dihydro-1H-pyrazol
Publikováno v:
Crystallography Reports. 63:937-941
Dege, Necmi/0000-0003-0660-4721; Kansiz, Sevgi/0000-0002-8433-7975 WOS: 000452155100012 The molecule of the title pyrazole derivative, 3,5-diphenyl-1-(phenylacetyl)-4,5-dihydro-1H-pyrazol, C23H20N2O, is twisted. The compound crystallizes in the monoc
The hybrid method of the Electron-Conformational Genetic Algorithm (EC-GA) was used to determine the pharmacophore groups and to estimate anticancer activity in isatin derivatives using a robust 4D-QSAR software (EMRE). To build the model, each compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f160f8b35ee6a74604136957e78998e3
https://aperta.ulakbim.gov.tr/record/230752
https://aperta.ulakbim.gov.tr/record/230752
Autor:
Onur Şahin, Vagolu Siva Krishna, Şengül Dilem Doğan, Hilal Doğan, Dharmarajan Sriram, Christian Lherbet, Emin Saripinar, Miyase Gözde Gündüz
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
European Journal of Medicinal Chemistry, 2020, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 188, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
European Journal of Medicinal Chemistry, 2020, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 188, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩
Tuberculosis, caused by Mycobacterium tuberculosis, is a serious infectious disease and remains a global health problem. There is an increasing need for the discovery of novel therapeutic agents for its treatment due to the emerging multi-drug resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf5e22e717cadc56fafb51179c19cb
https://avesis.erciyes.edu.tr/publication/details/63037046-9a04-4daa-aff2-c12c752fc604/oai
https://avesis.erciyes.edu.tr/publication/details/63037046-9a04-4daa-aff2-c12c752fc604/oai
The electron conformational genetic algorithm (EC-GA) method had been employed by distinguishing between enantiomers for the first time as a 4D-QSAR approach to reveal the pharmacophore (Pha) and to predict the bioactivity of the dipeptidyl boron com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4218c279908afef9eccd342eade80c
https://avesis.erciyes.edu.tr/publication/details/d374c6ee-6023-4110-b115-ac4778d60dde/oai
https://avesis.erciyes.edu.tr/publication/details/d374c6ee-6023-4110-b115-ac4778d60dde/oai
A series of imidazole derivatives were synthesized from two-component condensation reaction of phenylgloxal monohydrate with guanylhydrazone. They were characterized by spectroscopic and analytical techniques. The in vitro anticancer evaluation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8211dafb4e944951d88101e741f7abeb
https://avesis.erciyes.edu.tr/publication/details/a1eb2a1e-8351-4e93-ab21-157ea54fb442/oai
https://avesis.erciyes.edu.tr/publication/details/a1eb2a1e-8351-4e93-ab21-157ea54fb442/oai
Autor:
İlhan Özer İlhan, Emin Saripinar, Mehmet Çadir, Fatih Duman, Semiha Köprü, Fatma Öztürk Küp, Nazmiye Sabanci, Duygu Cemre Bulut
Background:An extensive study of 19 pyrazole derivatives were carried out based on the evaluation of DNA cleavage properties, antimicrobial and cytotoxic activities and 4D-QSAR analysis including pharmacophore modelling and bioactivity prediction by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45e4ea40d40e8d37d947c0a83acd28e
https://hdl.handle.net/20.500.12604/2273
https://hdl.handle.net/20.500.12604/2273