Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Emin Kuliyev"'
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12630- (2022)
Despite tremendous advances in genome editing technologies, generation of conditional alleles in mice has remained challenging. Recent studies in cells have successfully made use of short artificial introns to engineer conditional alleles. The approa
Externí odkaz:
https://doaj.org/article/c0ae5083c633440f9abcca0294b08ba1
Autor:
Yiannis Drosos, Geoffrey Neale, Jianming Ye, Leena Paul, Emin Kuliyev, Anirban Maitra, Anna L Means, M Kay Washington, Jerold Rehg, David B Finkelstein, Beatriz Sosa-Pineda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 3, Pp 172-184 (2016)
The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and infl
Externí odkaz:
https://doaj.org/article/5d87181b5cc147919209db8cc85fef3c
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178680 (2017)
A recent study identified SCYL1 as one of the components of the oncogenic STP axis, which promotes triple-negative breast cancer by regulating degradation of the REST tumor suppressor. Contrary to the findings of that study, herein we show by using 3
Externí odkaz:
https://doaj.org/article/7b1d115e636d4d069ad639babd6ece2d
Dissecting protein function in vivo: Engineering allelic series in mice using CRISPR-Cas9 technology
Publikováno v:
Methods in enzymology. 667
Allelic series are extremely valuable genetic tools to study gene function and identify essential structural features of gene products. In mice, allelic series have been engineered using conventional gene targeting in embryonic stem cells or chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9fc52b5071bc3ff68dccaaf01c3743aa
https://pubmed.ncbi.nlm.nih.gov/35525561
https://pubmed.ncbi.nlm.nih.gov/35525561
Dissecting protein function in vivo: Engineering allelic series in mice using CRISPR-Cas9 technology
Publikováno v:
Methods in Enzymology ISBN: 9780323915410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51da2e27e8e0a97e69d6e3e63172fded
https://doi.org/10.1016/bs.mie.2022.03.053
https://doi.org/10.1016/bs.mie.2022.03.053
Autor:
Clifford S. Guy, Peter Vogel, Sebastien Gingras, Emin Kuliyev, Stephane Pelletier, Sherie R. Howell
Publikováno v:
The Journal of Neuroscience. 38:2615-2630
Members of the SCY1-like (SCYL) family of protein kinases are evolutionarily conserved and ubiquitously expressed proteins characterized by an N-terminal pseudokinase domain, centrally located Huntingtin, elongation factor 3, protein phosphatase 2A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9ed568dbd5a32b9c9e59b7599d1d55
https://doi.org/10.1523/jneurosci.2282-17.2018
https://doi.org/10.1523/jneurosci.2282-17.2018
Autor:
Jerold E. Rehg, Geoffrey Neale, Emin Kuliyev, Anirban Maitra, Yiannis Drosos, M. Kay Washington, David B. Finkelstein, Jianming Ye, Beatriz Sosa-Pineda, Leena Paul, Anna L. Means
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 3, Pp 172-184 (2016)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ea7c5b8207b31b70c217961ad1acd3
http://www.sciencedirect.com/science/article/pii/S1476558616000221
http://www.sciencedirect.com/science/article/pii/S1476558616000221
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0178680 (2017)
PLoS ONE, Vol 12, Iss 6, p e0178680 (2017)
A recent study identified SCYL1 as one of the components of the oncogenic STP axis, which promotes triple-negative breast cancer by regulating degradation of the REST tumor suppressor. Contrary to the findings of that study, herein we show by using 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceae8cf88356c34add54d7a10493d6e4
http://europepmc.org/articles/PMC5453557
http://europepmc.org/articles/PMC5453557
Autor:
Marc Valentine, Paul E. Mead, Andrea P. Subhawong, Emin Kuliyev, Taylor D. Archer, Joanne R. Doherty, Donald Yergeau, Haiqing Zhu, Michelle R. Johnson Hamlet, Clair M. Kelley
Publikováno v:
Developmental Dynamics. 238:1727-1743
Transposon-based integration systems have been widely used for genetic manipulation of invertebrate and plant model systems. In the past decade, these powerful tools have begun to be used in vertebrates for transgenesis, insertional mutagenesis, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea47c9ca2990cac94ec095764d6541f5
https://doi.org/10.1002/dvdy.21994
https://doi.org/10.1002/dvdy.21994
Publikováno v:
Gene Expression Patterns. 6:420-425
Cytokine signaling plays an important role in the survival and differentiation of vertebrate hematopoietic cells. In red blood cells, erythropoietin is a key component of the differentiation program and maintains the homeostasis of the erythroid comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d92554ba4656ac0e32224253db3ae33
https://doi.org/10.1016/j.modgep.2005.09.004
https://doi.org/10.1016/j.modgep.2005.09.004