Výsledky vyhledávání - "Emily Zhi-Yun Keung"

Randomized phase II study of neoadjuvant checkpoint blockade for surgically resectable undifferentiated pleomorphic sarcoma (UPS) and dedifferentiated liposarcoma (DDLPS): Survival results after 2 years of follow-up and intratumoral B-cell receptor (BCR) correlates

Publikováno v: Journal of Clinical Oncology. 40:LBA11501-LBA11501

LBA11501 Background: We conducted a randomized, phase II non-comparative trial evaluating the efficacy of neoadjuvant ICB [nivolumab or ipilimumab/nivolumab] in patients (pts) with surgically resectable retroperitoneal DDLPS or extremity/truncal UPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f312a0c7134e62137bfefe2a052fedd
https://doi.org/10.1200/jco.2022.40.17_suppl.lba11501

Zobrazit plný text záznamu

Identifying gut microbial signatures associated with B cells and tertiary lymphoid structures (TLS) in the tumor microenvironment (TME) in response to immune checkpoint blockade (ICB)

Publikováno v: Journal of Clinical Oncology. 40:2511-2511

2511 Background: While ICB has significantly improved clinical outcomes across several cancer types, only 15-20% of patients develop a durable response. Thus, novel and targetable biomarkers are needed. There is increased appreciation of the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5385f48774039aae8020148a526b7129
https://doi.org/10.1200/jco.2022.40.16_suppl.2511

Zobrazit plný text záznamu

Evaluating the impact of perioperative antibiotic prophylaxis on the microbiome in patients with cutaneous malignancy

Autor: Samuel Cass, Russell G. Witt, Xialong Meng, Pranoti Sahasrabhojane, Roland L. Bassett, Samuel Shelburne, Hsiu Yin Chang, Kinjal Somaiya, Kristi Mungovan, Sarah B. Fisher, Anthony Lucci, Jeffrey Edwin Lee, Merrick I. Ross, Jeffrey E. Gershenwald, Sheila Duncan, Nadim J. Ajami, Christina Lynn Roland, Jennifer Ann Wargo, Emily Zhi-Yun Keung

Publikováno v: Journal of Clinical Oncology. 40:TPS9602-TPS9602

TPS9602 Background: Preoperative antibiotic prophylaxis is commonly used to reduce surgical site infections (SSIs). However, the rate of SSIs following surgical procedures classified as clean is only 2-3%. Overuse of antibiotics is associated with se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0561ced6f67bb5ffe49b14070964ada7
https://doi.org/10.1200/jco.2022.40.16_suppl.tps9602

Zobrazit plný text záznamu

Autor: Heather G. Lyu, Heather A. Lillemoe, Yi-Ju Chiang, Emily Zhi-Yun Keung, Sa Thi Nguyen, Susan K. Peterson, Keila E Torres, Kelly Hunt, Barry W. Feig, Andrew Justin Bishop, Beverly Ashleigh Guadagnolo, Neeta Somaiah, Christina Lynn Roland, Christopher Scally

Publikováno v: Journal of Clinical Oncology. 40:11544-11544

11544 Background: In SARC028, patients with undifferentiated pleomorphic sarcoma (UPS) had a 40% overall response rate to pembrolizumab. Based on this, we conducted a randomized, phase II, non-comparative trial of combination nivolumab (nivo/RT) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc9f8b081c54c7ed2a245b6613a6df34
https://doi.org/10.1200/jco.2022.40.16_suppl.11544

Zobrazit plný text záznamu

A single-center experience of 98 patients (pts) with regionally metastatic Merkel cell carcinoma (MCC) of known (MCCKP) and unknown (MCCUP) primary at presentation

Autor: Brandon Cope, Russell G. Witt, Yi-Ju Chiang, Riyad Navroz Seervai, Sarah B. Fisher, Anthony Lucci, Jennifer Ann Wargo, Jeffrey Edwin Lee, Ahsan Saleem Farooqi, Andrew Bishop, Jeffrey E. Gershenwald, Ryan Goepfert, Michael K.K. Wong, Beverly Ashleigh Guadagnolo, Merrick I. Ross, Phyu P Aung, Deverati Mitra, Emily Zhi-Yun Keung

Publikováno v: Journal of Clinical Oncology. 40:9576-9576

9576 Background: MCC is a rare skin cancer historically associated with poor survival rates and which is increasing in incidence. A small number of retrospective series suggest that MCCUP may be associated with better prognosis than MCCKP while other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f82ab1fceec2e77a6ede47186e0db17e
https://doi.org/10.1200/jco.2022.40.16_suppl.9576

Zobrazit plný text záznamu

A phase II study of oral azacitidine (CC-486) in combination with pembrolizumab (PEMBRO) in patients (pts) with metastatic melanoma (MM)

Autor: Elizabeth M. Burton, Timothy Woody, Isabella Claudia Glitza, Rodabe Navroze Amaria, Emily Zhi-Yun Keung, Adi Diab, Sapna Pradyuman Patel, Michael K.K. Wong, Cassian Yee, Patrick Hwu, Jennifer Leigh McQuade, Scott Eric Woodman, Michael T. Tetzlaff, Michael A. Davies, Jennifer Ann Wargo, Kunal Rai, Hussein Abdul-Hassan Tawbi

Publikováno v: Journal of Clinical Oncology. 37:9560-9560

9560 Background: Immune checkpoint blockade (ICB) have improved survival for many pts with MM, offering durable responses in up to 35% of pts, but many have short-lived or no response ( > 40%). A potential immune escape mechanism is the subversion of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6d8956230d060f9b46a08386930038d
https://doi.org/10.1200/jco.2019.37.15_suppl.9560

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání