Výsledky vyhledávání - "Emily Zhen Guo"

Abstract 228: Comparison of the Effect of Local and Long-Distance Delivery Models for a School-Based Wellness Intervention on Health Behaviors of Middle School Students

Autor: Rachel Krallman, Jean DuRussel-Weston, Elizabeth A. Jackson, Daniel G. Montgomery, Sabrina Bernardo, Eva Kline-Rogers, Emily Zhen Guo, Kim A. Eagle

Publikováno v: Circulation: Cardiovascular Quality and Outcomes. 12

Background: Michigan’s upper peninsula (UP) is a remote area with only 3% of the state’s population, making it difficult to reach with health interventions. Nearly half of the UP counties have higher adult obesity rates than the state average. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b558deb79e6b9f423cec952227949e48
https://doi.org/10.1161/hcq.12.suppl_1.228

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A Novel Mechanism of Regulating the ATPase VPS4 by Its Cofactor LIP5 and the Endosomal Sorting Complex Required for Transport (ESCRT)-III Protein CHMP5

Autor: Zhaohui Xu, Yuan Liu, Yan Li, Cody Vild, Emily Zhen Guo

Publikováno v: Journal of Biological Chemistry. 290:7291-7303

Disassembly of the endosomal sorting complex required for transport (ESCRT) machinery from biological membranes is a critical final step in cellular processes that require the ESCRT function. This reaction is catalyzed by VPS4, an AAA-ATPase whose ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4fd2c1f2a013337f882f6d8950843c
https://doi.org/10.1074/jbc.m114.616730

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Mechanism of Vps4 hexamer function revealed by cryo-EM

Autor: Yan Li, Min Su, Jeffrey T. Tarrasch, Georgios Skiniotis, Xinqiang Ding, Zhaohui Xu, Emily Zhen Guo, Charles L. Brooks

Publikováno v: Science Advances

Cryo-EM structures illustrate a novel mechanism for Vps4-mediated disassembly of ESCRT-III filaments.
Vps4 is a member of AAA+ ATPase (adenosine triphosphatase associated with diverse cellular activities) that operates as an oligomer to disassem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791d5edd34c8a7decc48ad5b5116805c
https://pubmed.ncbi.nlm.nih.gov/28439563

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Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains

Autor: Zhaohui Xu, Emily Zhen Guo

Publikováno v: The Journal of biological chemistry. 290(13)

The endosomal sorting complex required for transport (ESCRT) machinery is responsible for membrane remodeling in a number of biological processes including multivesicular body biogenesis, cytokinesis, and enveloped virus budding. In mammalian cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb5a00b6bd1f3565ed08c1c7aca92b5
https://pubmed.ncbi.nlm.nih.gov/25657007

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