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of 4
pro vyhledávání: '"Emily Z. Pemberton"'
The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells
Autor:
Karl J Lewis, Xin Yi, Christian S Wright, Emily Z Pemberton, Whitney A Bullock, William R Thompson, Alexander G Robling
Publikováno v:
JBMR Plus, Vol 4, Iss 7, Pp n/a-n/a (2020)
ABSTRACT Bone relies on mechanical cues to build and maintain tissue composition and architecture. Our understanding of bone cell mechanotransduction continues to evolve, with a few key signaling pathways emerging as vital. Wnt/β‐catenin, for exam
Externí odkaz:
https://doaj.org/article/6299d5d7b70041cf8a6f6af606efa486
Autor:
Whitney A. Bullock, Xi He, Alexander G. Robling, Xinjun Zhang, Jung Min Hong, Daniel J. Horan, Emily Z. Pemberton, Roy B Choi, April M. Hoggatt
Publikováno v:
J Bone Miner Res
Wnt signaling plays a vital role in the cell biology of skeletal patterning, differentiation, and maintenance. Notum is a secreted member of the α/β-hydrolase superfamily that hydrolyzes the palmitoleoylate modification on Wnt proteins, thereby dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e2c15e6303f47503035f75a6408c4c
https://pubmed.ncbi.nlm.nih.gov/34223673
https://pubmed.ncbi.nlm.nih.gov/34223673
The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells
Autor:
Xin Yi, Alexander G. Robling, Whitney A. Bullock, Karl J. Lewis, Emily Z. Pemberton, Christian S. Wright, William R. Thompson
Publikováno v:
JBMR Plus
JBMR Plus, Vol 4, Iss 7, Pp n/a-n/a (2020)
JBMR Plus, Vol 4, Iss 7, Pp n/a-n/a (2020)
Bone relies on mechanical cues to build and maintain tissue composition and architecture. Our understanding of bone cell mechanotransduction continues to evolve, with a few key signaling pathways emerging as vital. Wnt/β‐catenin, for example, is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03161aa3539297558c4b0014bfc143ee
http://europepmc.org/articles/PMC7340445
http://europepmc.org/articles/PMC7340445
Autor:
Emily Z. Pemberton, Roy B Choi, Anthony B. Firulli, Whitney A. Bullock, Karl J. Lewis, Alexander G. Robling
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4427 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18
International Journal of Molecular Sciences
Volume 20
Issue 18
Wnt signaling plays a major role in bone metabolism. Advances in our understanding of secreted regulators of Wnt have yielded several therapeutic targets to stimulate osteoanabolism&mdash
the most promising of which is the Wnt inhibitor sclerost
the most promising of which is the Wnt inhibitor sclerost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66bc3e1d71b0295d6941bb566965d0f
https://doi.org/10.3390/ijms20184427
https://doi.org/10.3390/ijms20184427