Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome

Autor: Jorge E. Galán, Emily Z. Guo

Publikováno v: Proceedings of the National Academy of Sciences. 118

Type III secretion systems are multiprotein molecular machines required for the virulence of several important bacterial pathogens. The central element of these machines is the injectisome, a ∼5-Md multiprotein structure that mediates the delivery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55568f7bc3a5fd86331666c54f09a0e4
https://doi.org/10.1073/pnas.2114552118

A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion

Autor: Jan Zalesak, Birgit Habenstein, Thomas C. Marlovits, Mélanie Berbon, Antoine Loquet, Daniel C. Desrosiers, Emily Z. Guo, James Tolchard, Jorge E. Galán

Publikováno v: PLoS biology 17(7), e3000351-(2019). doi:10.1371/journal.pbio.3000351
Plos Biology
Plos Biology, 2019, 17 (7), pp.e3000351. ⟨10.1371/journal.pbio.3000351⟩
PLOS Biology
PLoS Biology, Vol 17, Iss 7, p e3000351 (2019)
PLoS Biology

Type III protein-secretion machines are essential for the interactions of many pathogenic or symbiotic bacterial species with their respective eukaryotic hosts. The core component of these machines is the injectisome, a multiprotein complex that medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb80a469b093eda6be53bcb488f3c73
https://doi.org/10.1371/journal.pbio.3000351