Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Emily Waigi"'
1
Lipoprotein lipase activation is a novel vascular anti-contractile mechanism that is lost in aging
Autor: Emily Wilson, Tiago Costa, Milene Fontes, Emily Waigi, Paul Townsend, Joseph McQuail, Camilla Wenceslau, Cameron McCarthy
Publikováno v: Physiology. 38
Increasing incidence of cardiovascular events with age can be attributed to the natural deterioration in organ function, and manifests through a range of vascular phenotypes that include, endothelial dysfunction, hypercontractility, stiffening and re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b741bae713a507a27cb26f04e2f5b8a1
https://doi.org/10.1152/physiol.2023.38.s1.5730035
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2
Lipoprotein lipase underlies the vascular anti-contractile effect of perivascular adipose tissue (PVAT)
Autor: Scott Corley, Tiago Costa, Emily Wilson, Emily Waigi, Camilla Wenceslau, Cameron McCarthy
Publikováno v: Physiology. 38
Physiologically, perivascular adipose tissue (PVAT) exerts an anti-contractile effect on the vasculature. This effect is mediated by the biosynthesis and liberation of a myriad of anti-contractile molecules (e.g., adipokines). However, this anti-cont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91c0b5a895f6d2290b980f6c09326701
https://doi.org/10.1152/physiol.2023.38.s1.5731358
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3
Fentanyl disrupts autoregulation and leads to exacerbated vasodilation in resistance arteries independent of mu-opioid receptor activation
Autor: Paul Townsend Jr, Laena Pernomian, Kawane Moura, Emily Waigi, Emily Wilson, Cameron McCarthy, Camilla Wenceslau
Publikováno v: Physiology. 38
According to the CDC, 107,375 people in the United States died of drug overdoses and poisonings in the 12-month period ending in January 2022 with 67% involving synthetic opioids like fentanyl. Recent studies have implicated the use of prescription o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3f8bbeee4d1ccf99983c9f28775fe5a
https://doi.org/10.1152/physiol.2023.38.s1.5795773
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4
Beta-hydroxybutyrate-induced vasodilation is mediated by Kv7 potassium channels
Autor: Seth Hester, Emily Waigi, Tiago Costa, Emily Wilson, Laena Pernomian, Milene Fontes, Camilla Wenceslau, Cameron McCarthy
Publikováno v: Physiology. 38
Despite the conflicting reports on ketogenic interventions at lowering blood pressure and ameliorating hypertension, we have previously demonstrated that the most abundant ketone body, β-hydroxybutyrate (βOHB) is a novel vasodilator. While the G-pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0ffb92131703ca5103e4ed33daf49d5
https://doi.org/10.1152/physiol.2023.38.s1.5734168
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5
Cardiac Hypertrophy and Vascular Dysfunction in Resistance Arteries Occurs Prior to the Onset of Hypertension in Schlager (BPH/2J) Mice
Autor: Laena Pernomian, Emily Waigi, Callie Clarke, Paul Townsend Jr, Emily Wilson, R. Clinton Webb, Cameron McCarthy, Camilla Wenceslau
Publikováno v: Physiology. 38
The Schlager inbred hypertensive (BPH/2J) mouse strain was developed by Gunther Schlager more than 45 years ago and have been recognized as a model of neurogenic hypertension. Activation of the sympathetic nervous system contributes to the maintainan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c1ad995eda99139ce09a83571038388
https://doi.org/10.1152/physiol.2023.38.s1.5731596
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6
Abstract P135: Specialized Pro-resolving Molecular Pathway Is Impaired In Resistance Arteries From Hypertensive Rats
Autor: Milene T Fontes, Jonnelle Edwards-Glenn, Tiago Costa, Emily Waigi, Laena Pernomian, R Clinton Webb, Cam McCarthy, Camilla F Wenceslau
Publikováno v: Hypertension. 79
Specialized pro-resolving mediators (SPMs), derived from essential fatty acids, are known to playa major role in the immune system, as immunoresolvents. SPMs reduce acute inflammatoryresponses and leads to the clearance of pathogens and dying cells.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55133e11c3194d31853337ed5c059385
https://doi.org/10.1161/hyp.79.suppl_1.p135
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7
Abstract P058: Endothelial Dysfunction And Increased Contractility In Resistance Arteries Occurs Prior To Onset Of Hypertension In Schlager (BPH/2J) Mice
Autor: Laena Pernomian, Emily Waigi, Cam McCarthy, Camilla F Wenceslau
Publikováno v: Hypertension. 79
Genetically hypertensive mice (BPH/2J) were developed by Gunther Schlager more than 45 years ago, and these mice have neurogenic hypertension. Seven-weeks-old male BPH/2J mice present elevations in systolic blood pressure (SBP), and its highest value
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b336332bc01f598a2f9a0fe789c445f3
https://doi.org/10.1161/hyp.79.suppl_1.p058
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8
Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice
Autor: Emily Waigi, Jonnelle M Edwards, Nicole R. Bearss, Jeremy C Tomcho, Camilla F. Wenceslau, Soyoung Cheon, Bina Joe, Cameron G McCarthy
Publikováno v: Journal of Vascular Research. 58:392-402
Recent studies have shown that chronic use of prescription or illicit opioids leads to an increased risk of cardiovascular events and pulmonary arterial hypertension. Indices of vascular age and arterial stiffness are also shown to be increased in op
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55f087bbc4a6b96635d666fce444acfd
https://doi.org/10.1159/000517555
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