Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emily Van Uden"'
Autor:
Margaret Mallory, Christine McGiffert, M. Alford, Isaac Veinbergs, Richard DeTeresa, Emily Van Uden, Robert A. Orlando, Eliezer Masliah
Publikováno v:
Experimental Neurology. 170:15-26
Apolipoprotein E (apoE) is known to bind to at least five receptors, including the low-density lipoprotein (LDL) receptor-related protein (LRP), very low density LDL receptor (VLDL-R), LDL-R, apoE receptor 2 (apoER2), and megalin/gp330. In this conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce442ea79441204ec59d77c5aeed7f7
https://doi.org/10.1006/exnr.2001.7684
https://doi.org/10.1006/exnr.2001.7684
Publikováno v:
Microscopy Research and Technique. 50:268-272
To date, mutations in three genes, beta-amyloid precursor protein (APP), presenilin 1 (PS1), and presenilin 2 (PS2), have been found to be causally related to familial Alzheimer's disease (AD). In addition, polymorphisms in three other genes (among o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab65d81b2c7b3f7c9b133e9685b0c57
https://doi.org/10.1002/1097-0029(20000815)50:4<268::aid-jemt3>3.0.co
https://doi.org/10.1002/1097-0029(20000815)50:4<268::aid-jemt3>3.0.co
Autor:
Isaac Veinbergs, Emily Van Uden, Eliezer Masliah, M. Alford, Edward Rockenstein, Margaret Mallory
The low-density lipoprotein receptor-related protein (LRP) is an abundant neuronal cell surface receptor that regulates amyloid beta-protein (Abeta) trafficking into the cell. Specifically, LRP binds secreted Abeta complexes and mediates its degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a8cc028fb6cb4343dfd565c40694b3
https://europepmc.org/articles/PMC6758061/
https://europepmc.org/articles/PMC6758061/
Autor:
Eliezer Masliah, Margaret Mallory, Robert A. Orlando, Emily Van Uden, John Van Uden, Edward Rockenstein, Yutaka Sagara
Publikováno v:
The Journal of biological chemistry. 275(39)
In order to delineate the neuroprotective role of the low density lipoprotein receptor-related protein (LRP) against amyloid beta-protein toxicity, studies were performed in C6 cells challenged with amyloid beta-protein in the presence or absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9a9bba7006b669aa015be1698034d3
https://pubmed.ncbi.nlm.nih.gov/10899157
https://pubmed.ncbi.nlm.nih.gov/10899157
Autor:
Edward Rockenstein, John R. Gilbert, Eliezer Masliah, Federico Licastro, Iain L. Campbell, Margaret Mallory, Isaac Veinbergs, Emily Van Uden, Carrie Kincaid
Publikováno v:
The American journal of pathology. 155(3)
This study was designed to explore the possible functional relationships between apolipoprotein E (apoE) and the protease inhibitor alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease. For this purpose, levels of EB22/5 (the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e295ae267d9772f362b1f030abf9bc
https://pubmed.ncbi.nlm.nih.gov/10487844
https://pubmed.ncbi.nlm.nih.gov/10487844
Autor:
Peter St George-Hyslop, George A. Carlson, Robert A. Orlando, Eliezer Masliah, David Westaway, Margaret Mallory, Edward Rockenstein, Emily Van Uden
Publikováno v:
Molecular and cellular neurosciences. 14(2)
Low density lipoprotein receptor-related protein (LRP) polymorphisms have recently been associated with an increased susceptibility of Alzheimer's disease (AD). Furthermore, LRP has been linked to molecules that confer susceptibility to AD (apolipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df9050725f18447ef9a8d548533fe28
https://pubmed.ncbi.nlm.nih.gov/10479411
https://pubmed.ncbi.nlm.nih.gov/10479411
Publikováno v:
Neuroscience letters. 249(2-3)
Recent studies suggest that apolipoprotein E (apoE) plays a neurotrophic role in the central nervous system and that an aberrant function of this molecule might result in neurodegeneration. Supporting this notion, apoE-deficient mice show neurodegene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd538ffbaf483e918de47b494f31e312
https://pubmed.ncbi.nlm.nih.gov/9682819
https://pubmed.ncbi.nlm.nih.gov/9682819