Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emily Tsutsumi"'
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304194 (2024)
Deficiencies in the ING4 tumor suppressor are associated with advanced stage tumors and poor patient survival in cancer. ING4 was shown to inhibit NF-kB in several cancers. As NF-kB is a key mediator of immune response, the ING4/NF-kB axis is likely
Externí odkaz:
https://doaj.org/article/e51079fd04424ee59031bfd8308e93f7
Publikováno v:
Mol Cell Biol
The chemokine Cxcl10 has been associated with poor prognosis in breast cancer, but the mechanism is not well understood. Our previous study has shown that CXCL10 was repressed by the ING4 tumor suppressor, suggesting a potential inverse functional re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72822a38c43b8f78d775111d5af9c19a
https://pubmed.ncbi.nlm.nih.gov/34871062
https://pubmed.ncbi.nlm.nih.gov/34871062
Autor:
Emily Tsutsumi, Suwon Kim
Publikováno v:
Cancer Research. 82:1522-1522
Cxcr3 is a G-protein coupled receptor expressed on various cell types including cancer cells. Cxcr3 is activated via binding of the chemokine Cxcl10, which mediates immune cell migration during normal immune response. Pharmacological inhibition of Cx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9e738bc5f374376b54b678ed29c01d
https://doi.org/10.1158/1538-7445.am2022-1522
https://doi.org/10.1158/1538-7445.am2022-1522
Publikováno v:
Cancer Research. 81:1978-1978
Cxcl10 is a chemokine that attracts immune cells by binding to the Cxcr3 receptor during a normal immune response. Cxcl10 or Cxcr3 expression has been correlated with aggressive breast cancer. Inhibitor of Growth 4 (ING4) has previously shown to repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d953e8584713127b9ab5807748a613df
https://doi.org/10.1158/1538-7445.am2021-1978
https://doi.org/10.1158/1538-7445.am2021-1978