Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Emily Trimby"'
Autor:
Denes Haase, John W. Cuozzo, John Barker, Pia Thommes, Michael Zahn, Avery Hunt, Vasileios Roumpelakis, Ying Zhang, Emily Trimby, Elise Gadouleau, Alain Dorali, Kostas Papadopoulos, Ole A. Andersen, Christoph E. Dumelin, Christel Compper, Michelle Southey, Christopher Lumley, Eric A. Sigel, Paolo A. Centrella, Barbara Mertins, Maisie Holbrow-Wilshaw, Spencer Napier, Adele Faulkner, Magali Dejob, Timothy Gorman, Alastair L Parkes, Boudewijn Dejonge, Thomas Krulle, Ricky Cain, Jennifer Williams, Boer Deng, Olivier Barbeau, Anthony D. Keefe, Sian Evans, David F. Corbett, Donnya Etheridge, Daniel B. Stein, Ryan M Dominic, Dawn M. Troast, Xianfu Li, Rajesh Odedra, Matthew A. Clark, Anthony P Dickie, Holly T Soutter, Kate Spear, Angelo Sanzone
Publikováno v:
Journal of Medicinal Chemistry. 64:14377-14425
This study describes a novel series of UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitors that was identified through affinity-mediated selection from a DNA-encoded compound library. The original hit was a selective inhibitor of Pseudomonas ae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561a3ec469b1a8704e6a0431f9d286c1
https://doi.org/10.1021/acs.jmedchem.1c00888
https://doi.org/10.1021/acs.jmedchem.1c00888
Autor:
M Dominic, Ryan, Alastair L, Parkes, David, Corbett, Anthony P, Dickie, Michelle, Southey, Ole A, Andersen, Daniel B, Stein, Olivier R, Barbeau, Angelo, Sanzone, Pia, Thommes, John, Barker, Ricky, Cain, Christel, Compper, Magali, Dejob, Alain, Dorali, Donnya, Etheridge, Sian, Evans, Adele, Faulkner, Elise, Gadouleau, Timothy, Gorman, Denes, Haase, Maisie, Holbrow-Wilshaw, Thomas, Krulle, Xianfu, Li, Christopher, Lumley, Barbara, Mertins, Spencer, Napier, Rajesh, Odedra, Kostas, Papadopoulos, Vasileios, Roumpelakis, Kate, Spear, Emily, Trimby, Jennifer, Williams, Michael, Zahn, Anthony D, Keefe, Ying, Zhang, Holly T, Soutter, Paolo A, Centrella, Matthew A, Clark, John W, Cuozzo, Christoph E, Dumelin, Boer, Deng, Avery, Hunt, Eric A, Sigel, Dawn M, Troast, Boudewijn L M, DeJonge
Publikováno v:
Journal of medicinal chemistry. 64(19)
This study describes a novel series of UDP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1d1f373433e8f065b03c7c212d95e83
https://pubmed.ncbi.nlm.nih.gov/34569791
https://pubmed.ncbi.nlm.nih.gov/34569791
Autor:
Stephen Birchall, Andrew Wise, Stephanie K. Sandiford, Emily Trimby, Tara Langley, Kirsty Skinner, Martti Vaara, David F. Corbett, Peter Warn, Alain Dorali, Troy Lister, Jennifer Williams
Publikováno v:
Antimicrobial agents and chemotherapy. 61(8)
Novel approaches for the treatment of multidrug-resistant Gram-negative bacterial infections are urgently required. One approach is to potentiate the efficacy of existing antibiotics whose spectrum of activity is limited by the permeability barrier p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c666b6e49849a248a76005c5b52c26
https://pubmed.ncbi.nlm.nih.gov/28533232
https://pubmed.ncbi.nlm.nih.gov/28533232