CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells

Autor: Julie O’Neal, Julie K. Ritchey, Matthew L. Cooper, Jessica Niswonger, L. Sofía González, Emily Street, Michael P. Rettig, Susan W. Gladney, Leah Gehrs, Ramzi Abboud, Julie L. Prior, Gabriel J. Haas, Reyka G. Jayasinghe, Li Ding, Armin Ghobadi, Ravi Vij, John F. DiPersio

Publikováno v: Leukemia. 36(6)

Despite improvement in treatment options for myeloma patients, including targeted immunotherapies, multiple myeloma remains a mostly incurable malignancy. High CS1 (SLAMF7) expression on myeloma cells and limited expression on normal cells makes it a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfb5f18588f85274eef94aca5132224
https://pubmed.ncbi.nlm.nih.gov/35422095

100 m Long Thermally Drawn Supercapacitor Fibers with Applications to 3D Printing and Textiles.

Autor: Khudiyev T; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Lee JT; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Department of Plant and Environmental New Resources, Kyung Hee University, Yongin, Gyeonggi-do, 446-701, Republic of Korea., Cox JR; Advanced Functional Fabrics of America, 12 Emily Street, Cambridge, MA, 02139, USA., Argentieri E; Advanced Functional Fabrics of America, 12 Emily Street, Cambridge, MA, 02139, USA., Loke G; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Yuan R; Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Noel GH; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Tatara R; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Yu Y; Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Logan F; Advanced Functional Fabrics of America, 12 Emily Street, Cambridge, MA, 02139, USA., Joannopoulos J; Department of Physics, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Shao-Horn Y; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Fink Y; Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Advanced Functional Fabrics of America, 12 Emily Street, Cambridge, MA, 02139, USA.; Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2020 Dec; Vol. 32 (49), pp. e2004971. Date of Electronic Publication: 2020 Nov 04.

Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.

Autor: Charoenthongtrakul S; Elixir Pharmaceuticals, Inc., 12 Emily Street, Cambridge, MA 02139, USA., Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, DiStefano PS, Geddes BJ

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2009 Jun; Vol. 329 (3), pp. 1178-86. Date of Electronic Publication: 2009 Feb 27.

The measurement of insulin secretion from isolated rodent islets of Langerhans.

Autor: Nolan AL; Elixir Pharmaceuticals, 12 Emily Street, Cambridge, MA 02139, USA. anolan@elixirpharm.com, O'Dowd JF

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2009; Vol. 560, pp. 43-51.

Why inhaling salt water changes what we exhale.

Autor: Watanabe W; Pulmatrix Inc., 12 Emily Street, Cambridge, MA 02139, USA., Thomas M, Clarke R, Klibanov AM, Langer R, Katstra J, Fuller GG, Griel LC, Fiegel J, Edwards D

Publikováno v: Journal of colloid and interface science [J Colloid Interface Sci] 2007 Mar 01; Vol. 307 (1), pp. 71-8. Date of Electronic Publication: 2006 Nov 15.