Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emily Selig"'
Autor:
George Louis Parra, Emily Selig, Antoine Baudin, Susan Weintraub, Bernard Fongang, David Libich
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 145-146 (2023)
OBJECTIVES/GOALS: The EWSR1-FLI1 gene fusion is implicated as a source of oncogenic activity in the majority of Ewing sarcoma (EwS) cases (>70%). Our studies will provide unparalleled insight into the transformative mechanics of EWS-FLI1 METHODS/STUD
Externí odkaz:
https://doaj.org/article/a9693f63fc4b4d5d8e7b9c32b87e5d7f
Autor:
Emily Selig, Courtney O. Zlatic, Yee-Foong Mok, Heath Ecroyd, Michael D. W. Griffin, Dezerae Cox, Paul R. Gooley
Publikováno v:
J Biol Chem
Small heat-shock proteins (sHSPs) are ubiquitously expressed molecular chaperones that inhibit amyloid fibril formation; however, their mechanisms of action remain poorly understood. sHSPs comprise a conserved α-crystallin domain flanked by variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15661659490b860fab188d1b13206da0
https://doi.org/10.1074/jbc.ra120.012748
https://doi.org/10.1074/jbc.ra120.012748
Autor:
Roohi Bhura, Emily Selig, Carmel Tovar, Matthew White, Renee Hoffman, Rachell Booth, David Libich
Publikováno v:
Journal of Biological Chemistry. 299:104245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9740429def8be20efb6d8da12802d8
https://doi.org/10.1016/j.jbc.2023.104245
https://doi.org/10.1016/j.jbc.2023.104245
Publikováno v:
Journal of Biological Chemistry. 299:104189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3e33b78ab9a53e0c10aabea26d6b98
https://doi.org/10.1016/j.jbc.2023.104189
https://doi.org/10.1016/j.jbc.2023.104189
Autor:
Michael D. W. Griffin, Jesse I. Mobbs, Riley D. Metcalfe, Paul R. Gooley, Emily Selig, Alex Di Paolo, David Stapleton
Publikováno v:
ChemBioChem. 19:229-238
The β subunit of adenosine monophosphate (AMP)-activated protein kinase (AMPK), which exists as two isoforms (β1 and β2) in humans, has a carbohydrate-binding module (CBM) that interacts with glycogen. Although the β1- and β2-CBMs are structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7969d9589d72c00b9a2741ed9c5adae1
https://doi.org/10.1002/cbic.201700589
https://doi.org/10.1002/cbic.201700589
The aggregation of α-synuclein (α-syn) into amyloid fibrils is associated with neurodegenerative diseases, collectively referred to as the α-synucleinopathies. In vivo, molecular chaperones, such as the small heat-shock proteins (sHsps), normally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f68a787a7db23bfd84e30f3bbab521
https://europepmc.org/articles/PMC5077198/
https://europepmc.org/articles/PMC5077198/
