Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emily Schenkein"'
Autor:
Amanda Linkous, Demosthenes Balamatsias, Matija Snuderl, Lincoln Edwards, Ken Miyaguchi, Teresa Milner, Batsheva Reich, Leona Cohen-Gould, Andrew Storaska, Yasumi Nakayama, Emily Schenkein, Richa Singhania, Stefano Cirigliano, Tarig Magdeldin, Ying Lin, Gouri Nanjangud, Kalyani Chadalavada, David Pisapia, Conor Liston, Howard A. Fine
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://doaj.org/article/f28ebd0f3f8540688e121a8ec45550af
Autor:
Stefano M. Cirigliano, Andrew J. Storaska, Ken Miyaguchi, Kalyani Chadalavada, Howard A. Fine, Amanda G. Linkous, Ying Lin, Gouri Nanjangud, Batsheva Reich, Leona Cohen-Gould, Teresa A. Milner, Richa Singhania, Yasumi Nakayama, Emily Schenkein, Tarig Magdeldin, Conor Liston, Matija Snuderl, Demosthenes Balamatsias, David J. Pisapia, Lincoln A. Edwards
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936188fe78fcd6c0dbaba6a700bb9cb6
http://www.sciencedirect.com/science/article/pii/S2211124719302426
http://www.sciencedirect.com/science/article/pii/S2211124719302426
Autor:
Yosup Rew, Xiaohui Du, Xuelei Yan, Minna D. Balbas, Erica L. Jackson, Daqing Sun, Qiuping Ye, Haiying Zhou, Emily Schenkein, Mallika Singh, Tatiana Zovorotinskaya, Valeria R. Fantin, Dan McWeeney, Liusheng Zhu, Chris Tran, Julio C. Medina, Nadine Jachan, John Eksterowicz
Publikováno v:
Cancer Research. 77:4172-4172
Androgen receptor (AR) signaling is crucial for normal development and homeostasis of the prostate, and is a key driver of prostate cancer initiation and progression. Hormone therapies that deprive the cancer of androgen have long been a mainstay of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89f5dcd7fb6ac13c3c46df5f099b4527
https://doi.org/10.1158/1538-7445.am2017-4172
https://doi.org/10.1158/1538-7445.am2017-4172
Autor:
Laurence Florens, Michele Pagano, Michael P. Washburn, Emily Schenkein, Shafi Kuchay, Anita Saraf, Shanshan Duan, Angelo Peschiaroli
Publikováno v:
Nature cell biology 15 (2013): 472–480. doi:10.1038/ncb2731
info:cnr-pdr/source/autori:Kuchay Shafi1,2; Duan Shanshan1; Schenkein Emily1; Peschiaroli Angelo1*; Saraf Anita2,3; Florens Laurence2,3; Washburn Michael P.2,3,4; Pagano Michele1,2/titolo:FBXL2-and PTPL1-mediated degradation of p110-free p85beta regulatory subunit controls the PI(3)K signalling cascade/doi:10.1038%2Fncb2731/rivista:Nature cell biology/anno:2013/pagina_da:472/pagina_a:480/intervallo_pagine:472–480/volume:15
info:cnr-pdr/source/autori:Kuchay Shafi1,2; Duan Shanshan1; Schenkein Emily1; Peschiaroli Angelo1*; Saraf Anita2,3; Florens Laurence2,3; Washburn Michael P.2,3,4; Pagano Michele1,2/titolo:FBXL2-and PTPL1-mediated degradation of p110-free p85beta regulatory subunit controls the PI(3)K signalling cascade/doi:10.1038%2Fncb2731/rivista:Nature cell biology/anno:2013/pagina_da:472/pagina_a:480/intervallo_pagine:472–480/volume:15
F-box proteins are the substrate-recognition subunits of SCF (Skp1/Cul1/F-box protein) ubiquitin ligase complexes. Purification of the F-box protein FBXL2 identified the PI(3)K regulatory subunit p85beta and tyrosine phosphatase PTPL1 as interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252e146363f890d2d8064bd7c28a6251
Autor:
Vivek K. Arora, Sumit K. Subudhi, Charles L. Sawyers, Neel Shah, Deyou Zheng, John Wongvipat, Emily Schenkein, Ling Cai, Rajmohan Murali, Minna D. Balbas, Chris Logothetis, Eleni Efstathiou
Publikováno v:
Cell. (6):1309-1322
SummaryThe treatment of advanced prostate cancer has been transformed by novel antiandrogen therapies such as enzalutamide. Here, we identify induction of glucocorticoid receptor (GR) expression as a common feature of drug-resistant tumors in a crede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212153d35e2c322c30c413a36addd827