Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emily S Syar"'
Autor:
Milan T. Tomic, Shauna Farr-Jones, Emily S. Syar, Nancy Niemuth, Dean Kobs, Michael J. Hackett, Yero Espinoza, Zacchary Martinez, Khanh Pham, Doris M. Snow, James D. Marks, Ronald R. Cobb
Publikováno v:
Toxins, Vol 13, Iss 9, p 671 (2021)
Botulinum neurotoxins (BoNT) are some of the most toxic proteins known and can induce respiratory failure requiring long-term intensive care. Treatment of botulism includes the administration of antitoxins. Monoclonal antibodies (mAbs) hold considera
Externí odkaz:
https://doaj.org/article/afc6f9a7ac414c809cee02b1394deb17
Autor:
Doris M. Snow, Ronald R. Cobb, Juan Martinez, Isaac Finger-Baker, Laura Collins, Sara Terpening, Emily S. Syar, Nancy Niemuth, Dean Kobs, Roy Barnewall, Shauna Farr-Jones, James D. Marks, Milan T. Tomic
Publikováno v:
Toxins, Vol 13, Iss 1, p 31 (2021)
Botulinum neurotoxins (BoNT) are extremely potent and can induce respiratory failure, requiring long-term intensive care to prevent death. Recombinant monoclonal antibodies (mAbs) hold considerable promise as BoNT therapeutics and prophylactics. In c
Externí odkaz:
https://doaj.org/article/f418db8c7f81479aaeacc484f74d01c3
Autor:
Milan T. Tomic, Yero Espinoza, Zachary Martinez, Khanh Pham, Ronald R. Cobb, Doris M. Snow, Christopher G. Earnhart, Traci Pals, Emily S. Syar, Nancy Niemuth, Dean J. Kobs, Shauna Farr-Jones, James D. Marks
Publikováno v:
Toxins, Vol 11, Iss 4, p 208 (2019)
Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD50 of ~1 ng/kg. Equine antitoxin has a half-life in circulation of less than 1 day and is limited to a treatment rather than a prevention indication. The developme
Externí odkaz:
https://doaj.org/article/b04e358af4e84978943d1cb454d2f44b
Autor:
Juan Daniel Martínez, Nancy A. Niemuth, Emily S Syar, Shauna Farr-Jones, Roy E. Barnewall, Milan T. Tomic, Ronald R. Cobb, Doris M Snow, Dean J. Kobs, Isaac Finger-Baker, Sara J Terpening, James D. Marks, Laura J. Collins
Publikováno v:
Toxins
Toxins, vol 13, iss 1
Toxins, Vol 13, Iss 31, p 31 (2021)
Volume 13
Issue 1
Toxins, vol 13, iss 1
Toxins, Vol 13, Iss 31, p 31 (2021)
Volume 13
Issue 1
Botulinum neurotoxins (BoNT) are extremely potent and can induce respiratory failure, requiring long-term intensive care to prevent death. Recombinant monoclonal antibodies (mAbs) hold considerable promise as BoNT therapeutics and prophylactics. In c
Autor:
Ronald R. Cobb, Traci Pals, Zachary Martinez, Emily S Syar, Shauna Farr-Jones, Yero Espinoza, Khanh Pham, Dean J. Kobs, Milan T. Tomic, Doris M Snow, James D. Marks, Christopher G. Earnhart, Nancy A. Niemuth
Publikováno v:
Toxins
Toxins, vol 11, iss 4
Volume 11
Issue 4
Toxins, Vol 11, Iss 4, p 208 (2019)
Toxins, vol 11, iss 4
Volume 11
Issue 4
Toxins, Vol 11, Iss 4, p 208 (2019)
Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD50 of ~1 ng/kg. Equine antitoxin has a half-life in circulation of less than 1 day and is limited to a treatment rather than a prevention indication. The developme
Autor:
Gregory V. Stark, Crystal M. Briscoe, Emily S Syar, Sukjoon Park, Kevin P. Tordoff, Roy E. Barnewall, Daniel C. Sanford, Laurence Lemiale-Biérinx, Jamie L. Austin, Mario H. Skiadopoulos, Boris Ionin, Michael S. Anderson, Vladimir Savransky
Publikováno v:
Infection and Immunity. 81:1152-1163
Nonhuman primates (NHPs) and rabbits are the animal models most commonly used to evaluate the efficacy of medical countermeasures against anthrax in support of licensure under the FDA's “Animal Rule.” However, a need for an alternative animal mod