Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Emily R. Workman"'
Autor:
Sarah A. Wolfe, Emily R. Workman, Chelcie F. Heaney, Farr Niere, Sanjeev Namjoshi, Luisa P. Cacheaux, Sean P. Farris, Michael R. Drew, Boris V. Zemelman, R. Adron Harris, Kimberly F. Raab-Graham
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Alcohol is thought to lead to neuroadaptive changes, although the underlying molecular mechanisms are unclear. Here, the authors find ethanol treatment alters GABAB-receptor expression via fragile-X mental retardation protein in mice, leading to anti
Externí odkaz:
https://doaj.org/article/e5cec5c74cef40f9abc05988792bd8e3
Publikováno v:
Brain Research. 1647:94-104
Healthy neurons have an optimal operating range, coded globally by the frequency of action potentials or locally by calcium. The maintenance of this range is governed by homeostatic plasticity. Here, we discuss how new approaches to treat depression
Autor:
Farr Niere, Luisa P. Cacheaux, Chelcie F. Heaney, Michael R. Drew, Sarah A. Wolfe, Sean P. Farris, Kimberly F. Raab-Graham, Emily R. Workman, R. Adron Harris, Sanjeev Namjoshi, Boris V. Zemelman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Alcohol promotes lasting neuroadaptive changes that may provide relief from depressive symptoms, often referred to as the self-medication hypothesis. However, the molecular/synaptic pathways that are shared by alcohol and antidepressants are unknown.
Autor:
Rasha Hammamieh, Seshamalini Srinivasan, Emily R. Workman, George Dmitrov, Aarti Gautam, John L. Clifford, Natasha M. Sosanya, Robert J. Christy, Raina Kumar, Roger Chavez, Andrianna Walsh
Publikováno v:
The FASEB Journal. 32
Autor:
P. C.G. Haddick, Geoffrey A. Dilly, Boris V. Zemelman, Kimberly F. Raab-Graham, Farr Niere, K. Bush, Emily R. Workman
Publikováno v:
Molecular Psychiatry
A single injection of N-methyl-D-aspartate receptor (NMDAR) antagonists produces a rapid antidepressant response. Lasting changes in the synapse structure and composition underlie the effectiveness of these drugs. We recently discovered that rapid an
Autor:
Emily R. Workman, Natasha M. Sosanya, Nora I. Perrone-Bizzozero, Kimberly F. Raab-Graham, Farr Niere, Luisa P. Cacheaux
The fate of a memory, whether stored or forgotten, is determined by the ability of an active or tagged synapse to undergo changes in synaptic efficacy requiring protein synthesis of plasticity-related proteins. A synapse can be tagged, but without th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930eff739df8356db1363aad4f720ea2
https://europepmc.org/articles/PMC4481233/
https://europepmc.org/articles/PMC4481233/
Publikováno v:
Alcohol. 60:235
Publikováno v:
Europe PubMed Central
Administration of N-methyl-D-aspartate receptors (NMDAR) antagonists initiates a rapid anti-depressant response requiring mammalian Target of Rapamycin Complex 1 (mTORC1) kinase; however the molecular mechanism is unknown. We have determined that upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae48621f4e60c48fd0c390604244ace
http://europepmc.org/abstract/med/23752093
http://europepmc.org/abstract/med/23752093