Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emily R. Stevenson"'
Autor:
Tushar Aggarwal, Alyssa Bellomo, Emily R. Stevenson, Julia Herbert, Debra L. Laskin, Andrew J. Gow, Enver Cagri Izgu
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103268- (2024)
Summary: Detection of nitrative stress is crucial to understanding redox signaling and pathophysiology. Dysregulated nitrative stress, which generates high levels of peroxynitrite, can damage lipid membranes and cause activation of proinflammatory pa
Externí odkaz:
https://doaj.org/article/ada23d3893a640f2be0b4ca150003d81
Autor:
Bryan Gutierrez, Tushar Aggarwal, Huseyin Erguven, M. Rhia L. Stone, Changjiang Guo, Alyssa Bellomo, Elena Abramova, Emily R. Stevenson, Debra L. Laskin, Andrew J. Gow, Enver Cagri Izgu
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108567- (2023)
Summary: Lipid membranes and lipid-rich organelles are targets of peroxynitrite (ONOO−), a highly reactive species generated under nitrative stress. We report a membrane-localized phospholipid (DPPC-TC-ONOO–) that allows the detection of ONOO−
Externí odkaz:
https://doaj.org/article/7d5e3267fe8549069245b5c1f20f2a6e
Autor:
Kristy L. Jackson, Geoffrey A. Head, Cindy Gueguen, Emily R. Stevenson, Kyungjoon Lim, Francine Z. Marques
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
It has been 45 years since Gunther Schlager used a cross breeding program in mice to develop inbred strains with high, normal, and low blood pressure (BPH/2, BPN/3, and BPL/1 respectively). Thus, it is timely to gather together the studies that have
Externí odkaz:
https://doaj.org/article/41885f8304da4333a475d0a2f55b216c
Publikováno v:
The FASEB Journal. 36
Autor:
Melissa L. Wilkinson, Changjiang Gou, Emily R. Stevenson, Elena Abramova, Bruce A. Freeman, Andrew J. Gow
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 382(3)
Acute lung injury (ALI) is characterized by epithelial damage, barrier dysfunction, and pulmonary edema. Macrophage activation and failure to resolve play a role in ALI; thus, macrophage phenotype modulation is a rational target for therapeutic inter
Autor:
Kyungjoon Lim, Nina Eikelis, Kristy L. Jackson, Gavin W. Lambert, Cindy Gueguen, Madeleine Paterson, Fadi J. Charchar, Geoffrey A. Head, Sandra L. Burke, Francine Z. Marques, Emily R. Stevenson
Publikováno v:
Hypertension Research. 43:1152-1164
BPH/2J mice are a genetic model of hypertension with overactivity of the sympathetic nervous system (SNS) and renin–angiotensin system (RAS). BPH/2J display higher renal renin mRNA and low levels of its negative regulator microRNA-181a (miR-181a).
Autor:
Kristy L. Jackson, Pamela J. Davern, Fadi J. Charchar, Sarah E. Phillips, Nina Eikelis, Gavin W. Lambert, Francine Z. Marques, Geoffrey A. Head, Cindy Gueguen, Emily R. Stevenson
Publikováno v:
Hypertension Research. 42:306-318
Schlager mice (BPH/2J) are hypertensive due to a greater contribution of the sympathetic nervous system (SNS) and renin-angiotensin system (RAS). The kidneys of BPH/2J are hyper-innervated suggesting renal nerves may contribute to the hypertension. W
Autor:
Kristy L, Jackson, Cindy, Gueguen, Kyungjoon, Lim, Nina, Eikelis, Emily R, Stevenson, Fadi J, Charchar, Gavin W, Lambert, Sandra L, Burke, Madeleine R, Paterson, Francine Z, Marques, Geoffrey A, Head
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 43(11)
BPH/2J mice are a genetic model of hypertension with overactivity of the sympathetic nervous system (SNS) and renin-angiotensin system (RAS). BPH/2J display higher renal renin mRNA and low levels of its negative regulator microRNA-181a (miR-181a). We
Autor:
Esther M.C. Johns, Roger G. Evans, Francine Z. Marques, Kristy L. Jackson, Pamela J. Davern, Geoffrey A. Head, Emily R. Stevenson
Publikováno v:
Journal of hypertension. 35(3)
Blood pressure high Schlager (BPH/2J) mice have neurogenic hypertension associated with differences in hypothalamic GABAA receptors compared with their normotensive counterparts (BPN/3J). Allopregnanolone is an endogenous neurosteroid reduced in chro