Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emily R. Rhodes"'
Autor:
Brian M. Petersen, Monica B. Kirby, Karson M. Chrispens, Olivia M. Irvin, Isabell K. Strawn, Cyrus M. Haas, Alexis M. Walker, Zachary T. Baumer, Sophia A. Ulmer, Edgardo Ayala, Emily R. Rhodes, Jenna J. Guthmiller, Paul J. Steiner, Timothy A. Whitehead
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Antibodies are engineerable quantities in medicine. Learning antibody molecular recognition would enable the in silico design of high affinity binders against nearly any proteinaceous surface. Yet, publicly available experiment antibody sequ
Externí odkaz:
https://doaj.org/article/ad885af6bfcd4b0ba2768a7ecb7b47e4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWith the flood of engineered antibodies, there is a heightened need to elucidate the structural features of antibodies that contribute to specificity, stability, and breadth. While antibody flexibility and interface angle have begun to be
Externí odkaz:
https://doaj.org/article/92fb3da14eb5413e943634e81846d800
Autor:
Brian M. Petersen, Sophia A. Ulmer, Emily R. Rhodes, Matias F. Gutierrez-Gonzalez, Brandon J. Dekosky, Kayla G. Sprenger, Timothy A. Whitehead
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Monoclonal antibodies (mAbs) are an important class of therapeutics used to treat cancer, inflammation, and infectious diseases. Identifying highly developable mAb sequences in silico could greatly reduce the time and cost required for therapeutic mA
Externí odkaz:
https://doaj.org/article/10a36cfa20ad4ada87c052c6b7e5c904
Autor:
Emily R. Rhodes, B. M. Petersen, S. A. Ulmer, Timothy A. Whitehead, M. F. Gutierrez Gonzalez, Kayla G. Sprenger, Brandon J. DeKosky
Monoclonal antibodies (mAbs) are an important class of therapeutics used to treat cancer, inflammation, and infectious diseases. Identifying highly developable mAb sequences in silico could greatly reduce the time and cost required for therapeutic mA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c81b95a547e83d3df014929a20d0ff7
https://doi.org/10.1101/2021.06.22.449488
https://doi.org/10.1101/2021.06.22.449488
Autor:
Linghang Peng, Paul J. Steiner, Irene M. Francino-Urdaniz, Alison C. Leonard, Shawn Barman, Emily R. Rhodes, Cyrus M. Haas, Fangzhu Zhao, Monica B Kirby, Joseph G. Jardine, Timothy A. Whitehead, Kayla G. Sprenger
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Cell Reports
article-version (status) pre
article-version (number) 1
Cell Reports
The potential emergence of SARS-CoV-2 Spike (S) escape mutants is a threat to reduce the efficacy of existing vaccines and neutralizing antibody (nAb) therapies. An understanding of the antibody/S escape mutation landscape is urgently needed to preem
Autor:
Carolyn M. Rodak, Anand D. Jayakaran, Trisha L. Moore, Ray David, Emily R. Rhodes, Jason R. Vogel
Publikováno v:
Water environment research : a research publication of the Water Environment FederationReferences. 92(10)
This review summarizes over 280 studies published in 2019 related to the characterization, control, and management of urban stormwater runoff. A summary of quantity and quality concerns is provided in the first section of the review, serving as the f