Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Emily R. Eden"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/85a91122fe8b4043ae719644692d3d3e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 (coronavirus disease 2019) pandemic, is a positive strand RNA (+RNA) virus. Like other +RNA viruses, SARS-CoV-2 is dependent on host cell metabolic machinery to s
Externí odkaz:
https://doaj.org/article/5c60017080e5488f900f2e468ffeaabf
Publikováno v:
Contact, Vol 2 (2019)
Delivery of low-density lipoprotein-derived cholesterol to the endoplasmic reticulum (ER) is essential for cholesterol homeostasis, yet the mechanism of this transport has largely remained elusive. Two recent reports shed some light on this process,
Externí odkaz:
https://doaj.org/article/22b1cc92bcfb41a380c6f5f916478031
Autor:
Christopher J. Stefan, William S. Trimble, Sergio Grinstein, Guillaume Drin, Karin Reinisch, Pietro De Camilli, Sarah Cohen, Alex M. Valm, Jennifer Lippincott-Schwartz, Tim P. Levine, David B. Iaea, Frederick R. Maxfield, Clare E. Futter, Emily R. Eden, Delphine Judith, Alexander R. van Vliet, Patrizia Agostinis, Sharon A. Tooze, Ayumu Sugiura, Heidi M. McBride
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-24 (2017)
Abstract Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and org
Externí odkaz:
https://doaj.org/article/57743286285748dc972d7417983b6f72
Autor:
Bethan S. Kilpatrick, Emily R. Eden, Leanne N. Hockey, Elizabeth Yates, Clare E. Futter, Sandip Patel
Publikováno v:
Cell Reports, Vol 18, Iss 7, Pp 1636-1645 (2017)
Membrane contact sites are regions of close apposition between organelles that facilitate information transfer. Here, we reveal an essential role for Ca2+ derived from the endo-lysosomal system in maintaining contact between endosomes and the endopla
Externí odkaz:
https://doaj.org/article/4766493fcd6e48f3a4b84fe0070f6fa8
Publikováno v:
Lysosomal Storage Disorders. :134-143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c124e91d8082a409c52c4833fcacd089
https://doi.org/10.1002/9781119697312.ch14
https://doi.org/10.1002/9781119697312.ch14
Autor:
Emily R. Eden, Clare E. Futter
Publikováno v:
Current Biology. 31:R1037-R1040
Summary Intraluminal vesicles accumulate within the endosomal lumen before lysosomal delivery or extracellular release. A new study reports the development of an elegant assay showing that these vesicles can escape from the endosomal lumen by ‘back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::605e41ce15e1f8d5ebee3c5af8875c87
https://doi.org/10.1016/j.cub.2021.07.055
https://doi.org/10.1016/j.cub.2021.07.055
Autor:
Elisa N. D. Palladino, Tytus Bernas, Christopher D. Green, Cynthia Weigel, Sandeep K. Singh, Can E. Senkal, Andrea Martello, John P. Kennelly, Erhard Bieberich, Peter Tontonoz, David A. Ford, Sheldon Milstien, Emily R. Eden, Sarah Spiegel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 39
Membrane contact sites (MCS), close membrane apposition between organelles, are platforms for interorganellar transfer of lipids including cholesterol, regulation of lipid homeostasis, and co-ordination of endocytic trafficking. Sphingosine kinases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e57cc00b35afca50bb2c58950af0af
https://doi.org/10.1073/pnas.2204396119
https://doi.org/10.1073/pnas.2204396119
Autor:
Duarte C. Barral, Leopoldo Staiano, Cláudia Guimas Almeida, Dan F. Cutler, Emily R. Eden, Clare E. Futter, Antony Galione, André R. A. Marques, Diego Luis Medina, Gennaro Napolitano, Carmine Settembre, Otília V. Vieira, Johannes M. F. G. Aerts, Peace Atakpa‐Adaji, Gemma Bruno, Antonella Capuozzo, Elvira De Leonibus, Chiara Di Malta, Cristina Escrevente, Alessandra Esposito, Paolo Grumati, Michael J. Hall, Rita O. Teodoro, Susana S. Lopes, J. Paul Luzio, Jlenia Monfregola, Sandro Montefusco, Frances M. Platt, Roman Polishchuck, Maria De Risi, Irene Sambri, Chiara Soldati, Miguel C. Seabra
Publikováno v:
Traffic, 23(5), 238-269. WILEY
Funder: Maratona da Saúde
Funder: Royal Society Wolfson
Funder: Wellcome; Id: http://dx.doi.org/10.13039/100010269
Since the discovery of lysosomes more than 70 years ago, much has been learned about the functions of these organelles.
Funder: Royal Society Wolfson
Funder: Wellcome; Id: http://dx.doi.org/10.13039/100010269
Since the discovery of lysosomes more than 70 years ago, much has been learned about the functions of these organelles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5d231f62a432f3d967c8e877aee060
https://hdl.handle.net/1887/3479665
https://hdl.handle.net/1887/3479665
Autor:
Frances M. Platt, David Smith, Lauren Morris, Oscar C. W. Chen, Lianne C. Davis, Alexandria Colaco, Emily R. Eden, Forbes D. Porter, Patricia W. Tynan, Fedir N Kiskin, Anneliese O. Speak, Grant C. Churchill, Nicole Y. Farhat, Antony Galione
Publikováno v:
JIMD Reports, Vol 56, Iss 1, Pp 46-57 (2020)
JIMD Reports
JIMD Reports
Niemann‐Pick disease type C (NPC) is a neurodegenerative lysosomal storage disorder caused by mutations in either NPC1 (95% of cases) or NPC2. Reduced late endosome/lysosome calcium (Ca2+) levels and the accumulation of unesterified cholesterol and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf5d7b8717f1babb1787871291c7958
https://doaj.org/article/0e1a6412d2a14de1a7841b940a26ea33
https://doaj.org/article/0e1a6412d2a14de1a7841b940a26ea33