Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emily R. Driver"'
Autor:
Donald R Hoff, Gavin J Ryan, Emily R Driver, Cornelius C Ssemakulu, Mary A De Groote, Randall J Basaraba, Anne J Lenaerts
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17550 (2011)
The lengthy treatment regimen for tuberculosis is necessary to eradicate a small sub-population of M. tuberculosis that persists in certain host locations under drug pressure. Limited information is available on persisting bacilli and their location
Externí odkaz:
https://doaj.org/article/7e260286e0754dd092da42678453fb1b
Autor:
Gavin J Ryan, Donald R Hoff, Emily R Driver, Martin I Voskuil, Mercedes Gonzalez-Juarrero, Randall J Basaraba, Dean C Crick, John S Spencer, Anne J Lenaerts
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11108 (2010)
A unique hallmark of tuberculosis is the granulomatous lesions formed in the lung. Granulomas can be heterogeneous in nature and can develop a necrotic, hypoxic core which is surrounded by an acellular, fibrotic rim. Studying bacilli in this in vivo
Externí odkaz:
https://doaj.org/article/442a27b408104ffd819da86b3a48cd29
Autor:
Randall J. Basaraba, Scott M. Irwin, Anne J. Lenaerts, Eric L. Nuermberger, Edward R. Lyon, Mercedes Gonzalez-Juarrero, Emily R. Driver, Christopher A. Schrupp, Gavin J. Ryan
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 6, Pp 591-602 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Cost-effective animal models that accurately reflect the pathological progression of pulmonary tuberculosis are needed to screen and evaluate novel tuberculosis drugs and drug regimens. Pulmonary disease in humans is characterized by a number of hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a24b7f7531134989c69caa1fc8b096
http://dmm.biologists.org/content/8/6/591
http://dmm.biologists.org/content/8/6/591
Autor:
Gavin J. Ryan, Anne J. Lenaerts, Igor Kramnik, Emily R. Driver, Donald R. Hoff, Scott M. Irwin, Randall J. Basaraba
Persistence of Mycobacterium tuberculosis remains a significant challenge for the effective treatment of tuberculosis in humans. In animals that develop necrotic lung lesions following infection with M. tuberculosis , drug-tolerant bacilli are presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57550d582f8bc23b836e5112277c7874
https://europepmc.org/articles/PMC3370740/
https://europepmc.org/articles/PMC3370740/
Autor:
Anne J. Lenaerts, Gavin J. Ryan, Randall J. Basaraba, Donald R. Hoff, Emily R. Driver, Cornelius C. Ssemakulu, Mary Ann De Groote
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17550 (2011)
PLoS ONE
PLoS ONE
The lengthy treatment regimen for tuberculosis is necessary to eradicate a small sub-population of M. tuberculosis that persists in certain host locations under drug pressure. Limited information is available on persisting bacilli and their location
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a502034f85f2629943f5ec9663532d
http://europepmc.org/articles/PMC3061964?pdf=render
http://europepmc.org/articles/PMC3061964?pdf=render
Autor:
Mercedes Gonzalez-Juarrero, Martin I. Voskuil, Gavin J. Ryan, Emily R. Driver, John S. Spencer, Anne J. Lenaerts, Donald R. Hoff, Dean C. Crick, Randall J. Basaraba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11108 (2010)
PLoS ONE, Vol 5, Iss 6, p e11108 (2010)
A unique hallmark of tuberculosis is the granulomatous lesions formed in the lung. Granulomas can be heterogeneous in nature and can develop a necrotic, hypoxic core which is surrounded by an acellular, fibrotic rim. Studying bacilli in this in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8e60f8f2069b432a8243d7995bd7d8
https://pubmed.ncbi.nlm.nih.gov/20559431
https://pubmed.ncbi.nlm.nih.gov/20559431
Autor:
Anne J. Lenaerts, Ian M. Orme, Gavin J. Ryan, Charles A. Peloquin, Randall J. Basaraba, Emily R. Driver, Megan L. Caraway, Elizabeth J. Brooks, Donald R. Hoff
Publikováno v:
Antimicrobial agents and chemotherapy. 52(11)
Metronidazole, which is used for the treatment of infections caused by anaerobic organisms, was evaluated in Mycobacterium tuberculosis -infected guinea pigs. M. tuberculosis can adapt to hypoxia, which is present in the primary lesions of infected g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9cb71d46bef1474e231ca6b99e2c60
https://pubmed.ncbi.nlm.nih.gov/18694944
https://pubmed.ncbi.nlm.nih.gov/18694944