Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emily R Roberts"'
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006135 (2016)
Poor maintenance of cytotoxic factor expression among HIV-specific CD8+ T cells, in part caused by dysregulated expression of the transcription factor T-bet, is associated with HIV disease progression. However, the precise evolution and context in wh
Externí odkaz:
https://doaj.org/article/2d86024d41914787afed2d7dc7176bc3
Autor:
Emily R Roberts, Kelly Jean Thomas
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 6, Iss 7 (2013)
The influence of mitochondria in human health and disease is a rapidly expanding topic in the scientific literature due to their integral roles in cellular death and survival. Mitochondrial biology and alterations in function were first linked to can
Externí odkaz:
https://doaj.org/article/04f6381f6cf14d7094269bc190bb1cbd
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8980eb34badc6a19f61bbce026e67
https://doi.org/10.1158/2767-9764.c.6550691
https://doi.org/10.1158/2767-9764.c.6550691
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary tables: Supplementary Table 1 describes where cells were obtained from and details of authentication and mycoplasma testing dates. Supplementary Table 2 shows TAK-676 potency in cynomolgus monkey, human, mouse, and rat STING via time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc816185704d6e9271927a182bdb34f
https://doi.org/10.1158/2767-9764.22544570
https://doi.org/10.1158/2767-9764.22544570
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary figures: Supplementary Figure 1 shows cell viability of human monocyte-derived dendric cells and mouse bone marrow dendritic cells. Supplementary Figure 2 shows mean plasma and tumor concentration-time curves of TAK-676 in BALB/C mice (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f557c397f065d58fee34ecc2828d809
https://doi.org/10.1158/2767-9764.22544576
https://doi.org/10.1158/2767-9764.22544576
Autor:
Laura K Wiley, Jonathan A Shortt, Emily R Roberts, Jan Lowery, Elizabeth Kudron, Meng Lin, David A Mayer, Melissa P Wilson, Tonya M Brunetti, Sameer Chavan, Tzu L Phang, Nikita Pozdeyev, Joseph Lesny, Stephen J Wicks, Ethan Moore, Joshua L Morgenstern, Alanna N Roff, Elise L Shalowitz, Adrian Stewart, Cole Williams, Michelle N Edelmann, Madelyne Hull, J. Tacker Patton, Lisen Axell, Lisa Ku, Yee Ming Lee, Jean Jirikowic, Anna Tanaka, Emily Todd, Sarah White, Brett Peterson, Emily Hearst, Richard Zane, Casey S Greene, Rasika Mathias, Marilyn Coors, Matthew RG Taylor, Debashis Ghosh, Michael G Kahn, Ian M Brooks, Christina L Aquilante, David Kao, Nicholas Rafaels, Kristy Crooks, Steve Hess, Kathleen C Barnes, Christopher R Gignoux
Precision medicine initiatives across the globe have led to a revolution of repositories linking large-scale genomic data with electronic health records, enabling genomic analyses across the entire phenome. Many of these initiatives focus solely on r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8471beca0a0725070c7875392f2fbde9
https://doi.org/10.1101/2022.06.09.22276222
https://doi.org/10.1101/2022.06.09.22276222
Autor:
Rachel Weber, Andrew Schmanski, Marilyn E. Coors, Kristy Crooks, Jaron Arbet, Kathleen C. Barnes, Stephen J. Wicks, Matthew R.G. Taylor, Emily R. Roberts
Publikováno v:
Journal of Genetic Counseling. 30:257-267
The number of institutional and governmental biobanks and the target enrollment sizes of modern biobanks are increasing, affording more opportunities for the public to participate in biobanking efforts. In parallel with these expansions are pressures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a480ef068bba1285c6aa3e3d01cbb93
https://doi.org/10.1002/jgc4.1316
https://doi.org/10.1002/jgc4.1316
Autor:
Steven J. Hess, David P. Kao, Kristy Crooks, Emily C. Hearst, Matthew J. Rioth, Jan T. Lowery, Yee Ming Lee, Chen-Tan Lin, Emily R. Roberts, Ina Liko, Matthew R.G. Taylor, Elizabeth L. Kudron, Connie Williamson, Kathleen C. Barnes, Rasika A. Mathias, Katy E. Trinkley, Christina L. Aquilante, Andrew A. Monte, Nicholas Rafaels
Publikováno v:
Pharmacogenomics
In recent years, the genomics community has witnessed the growth of large research biobanks, which collect DNA samples for research purposes. Depending on how and where the samples are genotyped, biobanks also offer the potential opportunity to retur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995c5471abd5524931d49582a4f52be4
https://doi.org/10.2217/pgs-2020-0007
https://doi.org/10.2217/pgs-2020-0007
Autor:
Vicky A. Appleman, Allison J. Berger, Emily R. Roberts, Angel E. Maldonado-Lopez, Michelle L. Ganno, Camilla I. Christensen, Tiquella Hatten, Yosuke Sato, Michael H. Shaw, Karim S. Malek, Neil B. Lineberry, Adnan O. Abu-Yousif, Richard C. Gregory
Publikováno v:
Cancer Research. 82:3448-3448
Robust interferon (IFN) signaling is integral for productive immune-mediated anti-tumor responses; however, impaired IFN signaling has been linked to checkpoint inhibitor (CPI) resistance. The cyclic GMP-AMP Synthase (cGAS)-STimulator of InterferoN G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791e47ed83283036773eb7b90ab2fc29
https://doi.org/10.1158/1538-7445.am2022-3448
https://doi.org/10.1158/1538-7445.am2022-3448
Autor:
Kelly Bookman, Eleanor Mills, Megan Westmoreland, Michael DeVivo, Andrew Hopkinson, Michael J. Ames, Emily R. Roberts, Brandon J. Sonn, Kathleen C. Barnes, Shelby K. Shelton, Mark Chavez, Laurie Blumberg Romero, Kristy Crooks, Makayla Welham, Alison Lakin, Adit A. Ginde, Stephen J. Wicks, Matthew R.G. Taylor, Justin Oeth, Richard D. Zane, Jessica Saben, Andrew A. Monte, John Heldens
Publikováno v:
Acad Emerg Med
The Emergency Medicine Specimen Bank (EMSB) was developed to facilitate precision medicine in acute care. The EMSB is a biorepository of clinical health data and biospecimens collected from all adult, English- or Spanish-speaking individuals who are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebbe5e5f4d54910f25304be991dbd03
https://doi.org/10.1111/acem.13620
https://doi.org/10.1111/acem.13620