Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Emily R Mears"'
Autor:
Yamila N Torres Cleuren, Chee Kiang Ewe, Kyle C Chipman, Emily R Mears, Cricket G Wood, Coco Emma Alma Al-Alami, Melissa R Alcorn, Thomas L Turner, Pradeep M Joshi, Russell G Snell, Joel H Rothman
Publikováno v:
eLife, Vol 8 (2019)
Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, into the C. elegans endode
Externí odkaz:
https://doaj.org/article/ae1998556e3f4e91b5cbe8ea4e9c95dd
Autor:
Alexander J. Trevarton, Emily R. Mears, Janelle Moody, Thomas J. Lopdell, Thaize Q. Chometon, John A. Taylor, Carol J. Wang, Mathew D. Littlejohn, Russell G. Snell
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 59:163-165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64bffed177626e558b60bfe77f08eb09
https://doi.org/10.1007/s11626-023-00756-4
https://doi.org/10.1007/s11626-023-00756-4
Autor:
Miguel E. Quiñones-Mateu, Emily R Mears, See Tarn Woon, Klaus Lehnert, Shyamal C. Das, Russell G. Snell, William G. H. Abbott, Hilary Longhurst, Anthony Jordan, Richard Steele, Natalie J. Medlicott, Rohan Ameratunga, Euphemia Leung
Publikováno v:
Expert Review of Clinical Immunology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Background: COVID-19 has caused calamitous health, economic and societal consequences globally. Currently, there is no effective treatment for the infection. Areas covered: We have recently described the NZACE2-Pātari project, which seeks to adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434fb25065d6922613933855cb2f7141
http://europepmc.org/articles/PMC8127172
http://europepmc.org/articles/PMC8127172
Autor:
Richard L.M. Faull, John F. Pearson, James F. Gusella, Rudiger Brauning, Clive J. McLaughlan, Stefano Patassini, Skye R. Rudiger, Benjamin T Day, Paul S. MacLean, Richard D. Unwin, Garth J. S. Cooper, Emily R Mears, Paul J. Verma, Henry J. Waldvogel, Simon C Bawden, Suzanne J. Reid, Marcy E. MacDonald, Matthew J Grant, Renee R. Handley, Russell G. Snell
Publikováno v:
Journal of Huntington's Disease
Background: The pathological mechanism of cellular dysfunction and death in Huntington’s disease (HD) is not well defined. Our transgenic HD sheep model (OVT73) was generated to investigate these mechanisms and for therapeutic testing. One particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08657a0a43b835bb449c5a0dde17f5
https://pubmed.ncbi.nlm.nih.gov/34420978
https://pubmed.ncbi.nlm.nih.gov/34420978
Autor:
Pradeep M. Joshi, Coco Emma Alma Al-Alami, Yamila N. Torres Cleuren, Kyle C. Chipman, Chee Kiang Ewe, Emily R Mears, Cricket G. Wood, Joel H. Rothman, Russell G. Snell, Thomas L. Turner, Melissa R. Alcorn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ac639ba217c73f71c04f5ba4f22b94
https://doi.org/10.7554/elife.48220.029
https://doi.org/10.7554/elife.48220.029
Autor:
Pradeep M. Joshi, Emily R Mears, Cricket G. Wood, Thomas L. Turner, Kyle C. Chipman, Russell G. Snell, Yamila N. Torres Cleuren, Coco Emma Alma Al-Alami, Melissa R. Alcorn, Chee Kiang Ewe, Joel H. Rothman
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLIFE
eLife, Vol 8 (2019)
eLIFE
Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, into the C. elegans endode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b1b9c32ca9c9deca277d82673ea67c
https://doi.org/10.1101/628495
https://doi.org/10.1101/628495
Autor:
Renee R, Handley, Suzanne J, Reid, Rudiger, Brauning, Paul, Maclean, Emily R, Mears, Imche, Fourie, Stefano, Patassini, Garth J S, Cooper, Skye R, Rudiger, Clive J, McLaughlan, Paul J, Verma, James F, Gusella, Marcy E, MacDonald, Henry J, Waldvogel, C Simon, Bawden, Richard L M, Faull, Russell G, Snell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(52)
We present evidence for the presymptomatic dysregulation of urea metabolism in Huntington’s disease (HD). We identified increased levels of a urea transporter transcript and other osmotic regulators in the striatum of our prodromal sheep model of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca11c89799110a8c1298c3a591fb000c
https://pubmed.ncbi.nlm.nih.gov/29229845
https://pubmed.ncbi.nlm.nih.gov/29229845
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0003889 (2015)
PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0003889 (2015)
The current in vivo models for the utility and discovery of new potential anti-leishmanial drugs targeting Cutaneous Leishmaniasis (CL) differ vastly in their immunological responses to the disease and clinical presentation of symptoms. Animal models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87eeb0c7283607546d84b5cc3ed31fab
https://doi.org/10.1371/journal.pntd.0003889
https://doi.org/10.1371/journal.pntd.0003889