Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily P. Harrington"'
Autor:
Cassandre Labelle-Dumais, David J Dilworth, Emily P Harrington, Michelle de Leau, David Lyons, Zhyldyz Kabaeva, M Chiara Manzini, William B Dobyns, Christopher A Walsh, Daniel E Michele, Douglas B Gould
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002062 (2011)
Muscle-eye-brain disease (MEB) and Walker Warburg Syndrome (WWS) belong to a spectrum of autosomal recessive diseases characterized by ocular dysgenesis, neuronal migration defects, and congenital muscular dystrophy. Until now, the pathophysiology of
Externí odkaz:
https://doaj.org/article/798ef0f45e0e4478b76850bff3d09afd
Publikováno v:
Neurosci Lett
Chronic demyelination and the concomitant loss of trophic support and increased energy demands in axons are thought to contribute to neurodegeneration in a number of neurological diseases such as multiple sclerosis (MS). Adult oligodendrocyte precurs
Autor:
Eric J. Huang, David H. Rowitch, John C. Silbereis, Lawrence R. Shiow, Tracy J. Yuen, Stavros Lomvardas, Stephen P.J. Fancy, Sergio E. Baranzini, Emily P. Harrington
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 17, iss 4
Nature neuroscience, vol 17, iss 4
In colon cancer, mutation of the Wnt repressor APC (encoding adenomatous polyposis coli) leads to a state of aberrant and unrestricted high-activity signaling. However, the relevance of high Wnt tone in non-genetic human disease is unknown. Here we d
Autor:
Eric J. Huang, Jose Otero, Roel Nusse, Tracy J. Yuen, Stephen P.J. Fancy, Robin J.M. Franklin, John C. Silbereis, Charlotte C. Bruce, Sergio E. Baranzini, Emily P. Harrington, David H. Rowitch, Chao Zhao
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 14, iss 8
Nature neuroscience, vol 14, iss 8
Permanent damage to white matter tracts, comprising axons and myelinating oligodendrocytes, is an important component of brain injuries of the newborn that cause cerebral palsy and cognitive disabilities, as well as multiple sclerosis in adults. Howe
Autor:
Shwetal Mehta, Michael F. Kane, Emily P. Harrington, Christopher M. Taylor, Charles D. Stiles, David H. Rowitch, Dimphna H. Meijer, Hongye Liu
Publikováno v:
Nature reviews. Neuroscience. 13(12)
The basic helix-loop-helix transcription factors oligodendrocyte transcription factor 1 (OLIG1) and OLIG2 are structurally similar and, to a first approximation, coordinately expressed in the developing CNS and postnatal brain. Notwithstanding these
Autor:
Sovann Kaing, Robin J.M. Franklin, Stephen P.J. Fancy, Emily P. Harrington, David H. Rowitch, Chao Zhao
Objective Repair of myelin injury in multiple sclerosis may fail, resulting in chronic demyelination, axonal loss, and disease progression. As cellular pathways regulated by phosphatase and tensin homologue deleted on chromosome 10 (PTEN; eg, phospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bfd196a97c2f52980c8b22294ea4b3
https://europepmc.org/articles/PMC2966537/
https://europepmc.org/articles/PMC2966537/
Autor:
Christopher A. Walsh, Daniel E. Michele, David B. Lyons, Zhyldyz Kabaeva, Michelle de Leau, Douglas B. Gould, David J. Dilworth, M. Chiara Manzini, William B. Dobyns, Emily P. Harrington, Cassandre Labelle-Dumais
Publikováno v:
PLoS Genetics
PLoS genetics, vol 7, iss 5
PLoS Genetics, Vol 7, Iss 5, p e1002062 (2011)
Labelle-Dumais, C; Dilworth, DJ; Harrington, EP; de Leau, M; Lyons, D; Kabaeva, Z; et al.(2011). COL4A1 mutations cause ocular dysgenesis, neuronal localization defects, and myopathy in mice and walker-warburg syndrome in humans. PLoS Genetics, 7(5). doi: 10.1371/journal.pgen.1002062. UCSF: Retrieved from: http://www.escholarship.org/uc/item/67h6w6fd
PLoS genetics, vol 7, iss 5
PLoS Genetics, Vol 7, Iss 5, p e1002062 (2011)
Labelle-Dumais, C; Dilworth, DJ; Harrington, EP; de Leau, M; Lyons, D; Kabaeva, Z; et al.(2011). COL4A1 mutations cause ocular dysgenesis, neuronal localization defects, and myopathy in mice and walker-warburg syndrome in humans. PLoS Genetics, 7(5). doi: 10.1371/journal.pgen.1002062. UCSF: Retrieved from: http://www.escholarship.org/uc/item/67h6w6fd
Muscle-eye-brain disease (MEB) and Walker Warburg Syndrome (WWS) belong to a spectrum of autosomal recessive diseases characterized by ocular dysgenesis, neuronal migration defects, and congenital muscular dystrophy. Until now, the pathophysiology of
Publikováno v:
Epilepsia. 48
Summary: Purpose: Brain malformations are a common cause of intractable epilepsy and cognitive dysfunction in children. Prenatal exposure to the teratogen methylazoxymethanol (MAM) is a rodent model of brain malformation featuring loss of lamination,
Autor:
Tracy J. Yuen, John C. Silbereis, Eric J. Huang, Lawrence R. Shiow, David H. Rowitch, Sergio E. Baranzini, Stavros Lomvardas, Stephen P.J. Fancy, Emily P. Harrington
Publikováno v:
Nature Neuroscience. 17:1841-1841
Corrigendum: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer