Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Emily P Slater"'
Autor:
Chung Shing Rex Ha, Martina Müller-Nurasyid, Agnese Petrera, Stefanie M Hauck, Federico Marini, Detlef K Bartsch, Emily P Slater, Konstantin Strauch
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280399 (2023)
BackgroundThe low five-year survival rate of pancreatic ductal adenocarcinoma (PDAC) and the low diagnostic rate of early-stage PDAC via imaging highlight the need to discover novel biomarkers and improve the current screening procedures for early di
Externí odkaz:
https://doaj.org/article/96931f55022e484289322de847023aee
Autor:
Yesim Verel-Yilmaz, Juan Pablo Fernández, Agnes Schäfer, Sheila Nevermann, Lena Cook, Norman Gercke, Frederik Helmprobst, Christian Jaworek, Elke Pogge von Strandmann, Axel Pagenstecher, Detlef K. Bartsch, Jörg W. Bartsch, Emily P. Slater
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Due to a grim prognosis, there is an urgent need to detect pancreatic ductal adenocarcinoma (PDAC) prior to metastasis. However, reliable diagnostic imaging methods or biomarkers for PDAC or its precursor lesions are still scarce. ADAM8, a metallopro
Externí odkaz:
https://doaj.org/article/c3410811784b46d082946a8aab0a1d76
Autor:
Wulf Hildebrandt, Jan Keck, Simon Schmich, Gabriel A. Bonaterra, Beate Wilhelm, Hans Schwarzbach, Anna Eva, Mirjam Bertoune, Emily P. Slater, Volker Fendrich, Ralf Kinscherf
Publikováno v:
Cells, Vol 11, Iss 10, p 1607 (2022)
Skeletal muscle wasting critically impairs the survival and quality of life in patients with pancreatic ductal adenocarcinoma (PDAC). To identify the local factors initiating muscle wasting, we studied inflammation, fiber cross-sectional area (CSA),
Externí odkaz:
https://doaj.org/article/196ab6715f994981a37de440f24a3cc0
Autor:
Maren Stark, Marina Nicolai, Marina Tatura, Corinna U. Keber, Andreas Kaufmann, Ho‐Ryun Chung, Emily P. Slater, Christopher Heeschen, Rita T. Lawlor, Aldo Scarpa, Detlef K. Bartsch, Thomas M. Gress, Stefan Bauer, Malte Buchholz
Publikováno v:
Cancer Medicine. 12:8542-8556
Toll-like receptors (TLRs) are gaining attention for their potential to influence tumor biology both on the level of the tumor cells as well as on the level of the surrounding inflammatory stroma. Previous studies resulted in partly conflicting data
Autor:
Frederike S. Franke, Elvira Matthäi, Emily P. Slater, Christoph Schicker, Johannes Kruse, Detlef K. Bartsch
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Background Pancreatic cancer screening is recommended to individuals at risk (IAR) of familial pancreatic cancer (FPC) families, but little is known about the acceptance of such screening programs. Thus, the acceptance and psychological aspe
Externí odkaz:
https://doaj.org/article/a3f671d994c044ff9fdb1f1c7c8fd9bb
Autor:
Simon K. P. Schmich, Jan Keck, Gabriel A. Bonaterra, Mirjam Bertoune, Anna Adam, Beate Wilhelm, Emily P. Slater, Hans Schwarzbach, Volker Fendrich, Ralf Kinscherf, Wulf Hildebrandt
Publikováno v:
Biomedicines; Volume 11; Issue 3; Pages: 912
Cancer cachexia describes a syndrome of muscle wasting and lipolysis that is still largely untreatable and negatively impacts prognosis, mobility, and healthcare costs. Since upregulation of skeletal muscle monoamine-oxidase-A (MAO-A), a source of re
Autor:
Bettina Lehman, Elvira Matthäi, Norman Gercke, Ulrike W. Denzer, Jens Figiel, Timo Hess, Emily P. Slater, Detlef K. Bartsch
Publikováno v:
Familial Cancer.
Familial pancreatic cancer (FPC) is a rare hereditary tumor entity with broad phenotypic heterogeneity, including colorectal carcinoma (CRC) in some families. The underlying factors for this co-occurrence are still not well evaluated. FPC families in
Autor:
Ioannis Mintziras, Katharina Peer, Jannis Goerlach, Joachim N. Goebel, Annette Ramaswamy, Emily P. Slater, Peter Herbert Kann, Detlef Klaus Bartsch
Publikováno v:
Pancreas. 50:1450-1453
Autor:
Emily P. Slater, Konstantin Strauch, Susanne Rospleszcz, Annette Ramaswamy, Irene Esposito, Günter Klöppel, Elvira Matthäi, Kristin Heeger, Volker Fendrich, Peter Langer, Detlef K. Bartsch
Publikováno v:
Translational Oncology, Vol 7, Iss 4, Pp 464-471 (2014)
Screening programs are recommended for individuals at risk (IAR) from families with familial pancreatic cancer (FPC). However, reliable imaging methods or biomarkers for early diagnosis of pancreatic ductal adenocarcinoma (PC) or its precursor lesion
Externí odkaz:
https://doaj.org/article/6670dbf277e345b29b2b06300365b0a9
Autor:
Lena Cook, Marie Sengelmann, Birte Winkler, Constanze Nagl, Sarah Koch, Uwe Schlomann, Emily P. Slater, Miles A. Miller, Elke Pogge von Strandmann, Bastian Dörsam, Christian Preußer, Jörg W. Bartsch
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 1976
Publikationen im Open Access gefördert durch die UB
Publikationen im Open Access gefördert durch die UB
The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed