Výsledky vyhledávání - "Emily Nolton"

Platelet transfusions in a murine model of neonatal polymicrobial sepsis: Divergent effects on inflammation and mortality

Autor: Patricia Davenport, Hsuan‐Hao Fan, Emily Nolton, Henry A. Feldman, Viola Lorenz, Jorge Canas, Maikel Acosta‐Zaldívar, William Yakah, Connie Arthur, Camilia Martin, Sean Stowell, Julia Koehler, Donald Mager, Martha Sola‐Visner

Publikováno v: Transfusion. 62:1177-1187

Platelet transfusions (PTxs) are often given to septic preterm neonates at high platelet count thresholds in an attempt to reduce bleeding risk. However, the largest randomized controlled trial (RCT) of neonatal transfusion thresholds found higher mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11927dbaecbb4902d801f9c1ff8e5b57
https://doi.org/10.1111/trf.16895

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Development of gates to measure the immature platelet fraction in C57BL/6J mice using the Sysmex XN-V series multispecies hematology analyzer

Autor: Chiara-Aiyleen Badur, Patricia Davenport, Martha Sola-Visner, Viola Lorenz, Thi Minh Thi Do, Jorge Canas, Henry A. Feldman, Emily Nolton, Zhi-Jian Liu

Publikováno v: J Vet Diagn Invest

The immature platelet fraction (IPF) is a measure of newly released platelets, which has been used as a marker of platelet production in multiple human studies but is not widely available in multispecies analyzers. We developed gates to measure the I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c804d33c8aa5b01e9479b2479ebdb59c
https://doi.org/10.1177/10406387211027899

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Naegleria’smitotic spindles are built from unique tubulins and highlight core spindle features

Autor: Patricia Wadsworth, Luke M. Rice, Iva M. Tolić, Emily Nolton, Andrew Swafford, Katrina B. Velle, Monika Trupinić, Arian Ivec, Lillian K. Fritz-Laylin

Naegleria gruberiis a unicellular eukaryote whose evolutionary distance from animals and fungi has made it useful for developing hypotheses about the last common eukaryotic ancestor.Naegleriaamoebae lack a cytoplasmic microtubule cytoskeleton and ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29a32a44ec1ba804e8d40fec72719a04
https://doi.org/10.1101/2021.02.23.432318

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Pro-Inflammatory Effects of Platelet Transfusions in Newborn Mice with and without Underlying Inflammation

Autor: Patricia Davenport, Emily Nolton, Martha Sola-Visner, Zhi-Jian Liu, Henry A. Feldman

Publikováno v: Blood. 138:2146-2146

Platelet transfusions (PTx) are frequently given to thrombocytopenic preterm neonates at higher platelet count (PC) thresholds than those used in adults, in an attempt to reduce their bleeding risk. However, in the largest randomized trial of neonata

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02e40f16e074ad231ced74be7983adb9
https://doi.org/10.1182/blood-2021-147280

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Platelet Transfusions Can Increase or Decrease the Inflammatory Response and Mortality in a Murine Model of Neonatal Polymicrobial Sepsis

Autor: Julia Koehler, Emily Nolton, Maikel Acosta-Zaldívar, Viola Lorenz, Patricia Davenport, Hsuan-Hao Fan, Jorge Canas, Henry A. Feldman, Donald E. Mager, Camilia R. Martin, Sean R. Stowell, Martha Sola-Visner, William Yakah

Publikováno v: Blood. 138:2147-2147

Thrombocytopenia affects 18-35% of all neonates in the Neonatal Intensive Care Unit and ~70% of those born extremely prematurely, with sepsis being a frequent cause. Platelet transfusions (PTx) are frequently given to septic preterm neonates at highe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82bac395dee2c9d12c7c7c0600d63d0d
https://doi.org/10.1182/blood-2021-146582

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