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of 6
pro vyhledávání: '"Emily N Kirby"'
Autor:
Emily N. Kirby, Xavier B. Montin, Timothy P. Allen, Jaslan Densumite, Brooke N. Trowbridge, Michael R. Beard
Publikováno v:
Innate Immunity, Vol 30 (2024)
Interferon Stimulated Gene (ISG) expression plays a key role in the control of viral replication and development of a robust adaptive response. Understanding this dynamic relationship between the pathogen and host is critical to our understanding of
Externí odkaz:
https://doaj.org/article/70a7b7d456a945fc85b6e882e421f826
Publikováno v:
Viruses, Vol 13, Iss 11, p 2157 (2021)
Understanding the dynamic relationship between viral pathogens and cellular host factors is critical to furthering our knowledge of viral replication, disease mechanisms and development of anti-viral therapeutics. CRISPR genome editing technology has
Externí odkaz:
https://doaj.org/article/0448a9574aec439fa47a55d0b5cb1589
Autor:
Chuan Kok Lim, Ornella Romeo, Andrew P Chilver, Bang Manh Tran, Dustin J Flanagan, Emily N Kirby, James Breen, Elizabeth Vincan, Nadia Warner, Erin M McCartney, Mark B Van Der Hoek, Andrew Ruszkiewicz, Edmund Tse, Michael R Beard
Background & AimsCurrent HBVin vitromodel systems suffer from many physiological limitations that restrict understanding of complex viral-host interactions and thus prohibit prediction of diseasein vivo. We developed and assessed adult stem cell (AdS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401a2f7a9b5309afeddbf626642a4a12
https://doi.org/10.1101/2022.10.20.513112
https://doi.org/10.1101/2022.10.20.513112
Autor:
Stephen Pederson, Nicholas S. Eyre, Sonja Frölich, Ralf Bartenschlager, Byron Shue, Emily N. Kirby, Thu-Hien To, Berati Cerikan, Michael R. Beard, Abhilash I. Chiramel, Sonja M. Best
Publikováno v:
Journal of Virology
Cellular factors have important roles in all facets of the flavivirus replication cycle. Deciphering viral-host protein interactions is essential for understanding the flavivirus life cycle as well as development of effective antiviral strategies. To
Publikováno v:
Viruses
Viruses, Vol 13, Iss 2157, p 2157 (2021)
Viruses, Vol 13, Iss 2157, p 2157 (2021)
Understanding the dynamic relationship between viral pathogens and cellular host factors is critical to furthering our knowledge of viral replication, disease mechanisms and development of anti-viral therapeutics. CRISPR genome editing technology has
Autor:
Gustavo G. Bracho, Emily N. Kirby, Michael R. Beard, Peter A. White, Alice G. Russo, Daniel R. Anfiteatro, Amanda L. Aloia, Nicholas S. Eyre
Publikováno v:
Antimicrob Agents Chemother
Flaviviruses such as Zika virus (ZIKV), dengue virus (DENV), and West Nile virus (WNV) are major global pathogens for which safe and effective antiviral therapies are not currently available. To identify antiviral small molecules with well-characteri