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Autor:
Susanne Zellner, Grace Khuu, Louise Uoselis, Benjamin S. Padman, Runa S.J. Lindblom, Marvin Skulsuppaisarn, Thanh Ngoc Nguyen, Michael Lazarou, Emily M. Watts, Wai Kit Lam, Christian Behrends
Publikováno v:
Molecular cell. 81(9)
The sequestration of damaged mitochondria within double-membrane structures termed autophagosomes is a key step of PINK1/Parkin mitophagy. The ATG4 family of proteases are thought to regulate autophagosome formation exclusively by processing the ubiq