Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Emily M. Bradford"'
Autor:
Carolyn T. Jordan, Emily M. Bradford, Dennis C. Cheek, Mahesh Kudrimoti, Craig S. Miller, Molly H. Smith, J. Zach Hilt, Thomas D. Dziubla
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 1, Pp 47-53 (2021)
Abstract Translational animal models for oral mucositis (OM) are necessary to simulate and assess the bioclinical effects and response in humans. These models should simulate high levels of radiation exposure that leads to oxidative stress and inflam
Externí odkaz:
https://doaj.org/article/7a0a05f5a56e4efd8b4c4510fbcc3926
Autor:
Yuhuan Wang, Xiaoxi Liu, Sonja S. Pijut, Jianing Li, Jamie Horn, Emily M. Bradford, Markos Leggas, Terrence A. Barrett, Gregory A. Graf
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 4, Pp 810-820 (2015)
Previous studies suggest an interdependent relationship between liver and intestine for cholesterol elimination from the body. We hypothesized that a combination of ursodiol (Urso) and ezetimibe (EZ) could increase biliary secretion and reduce choles
Externí odkaz:
https://doaj.org/article/330248f3a7df4cc1b7f68d5d1bc00d80
Autor:
Craig S. Miller, Mahesh Kudrimoti, Emily M. Bradford, Molly Housley Smith, Carolyn T. Jordan, J. Zach Hilt, Thomas D. Dziubla, Dennis Cheek
Publikováno v:
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine, Vol 4, Iss 1, Pp 47-53 (2021)
Animal Models and Experimental Medicine, Vol 4, Iss 1, Pp 47-53 (2021)
Translational animal models for oral mucositis (OM) are necessary to simulate and assess the bioclinical effects and response in humans. These models should simulate high levels of radiation exposure that leads to oxidative stress and inflammatory‐
Autor:
Terrence A. Barrett, Amber L. Cloud, Preetika Sinh, Goo Lee, Isabelle G. De Plaen, Tatiana Goretsky, Vihang Patel, Evan B. Lynch, Guang Yu Yang, Olivia F. Lamping, Emily M. Bradford, David Williams, Elias Gounaris, Ajay Pal Singh, David Shealy, Stacy H. Ryu, Mary Pat Moyer
Publikováno v:
The Journal of Immunology. 199:1886-1897
TNF plays an integral role in inflammatory bowel disease (IBD), as evidenced by the dramatic therapeutic responses in Crohn’s disease (CD) patients induced by chimeric anti-TNF mAbs. However, treatment of CD patients with etanercept, a decoy recept
Publikováno v:
Gastroenterology. 158:S48-S49
Autor:
Austin T. Li, Xiaopeng Xiong, Li Tan, Terrence A. Barrett, Timothy L. Scott, Chi Wang, Tianyan Gao, Heidi L. Weiss, Emily M. Bradford, Teresa W.-M. Fan, Navdeep S. Chandel, Yang An Wen
Publikováno v:
Cell Death Differ
Cancer cells are known to upregulate aerobic glycolysis to promote growth, proliferation, and survival. However, the role of mitochondrial respiration in tumorigenesis remains elusive. Here we report that inhibition of mitochondrial function by silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fadd1b33a34eba0e4d4c9dfeb40a07
https://europepmc.org/articles/PMC6748256/
https://europepmc.org/articles/PMC6748256/
Autor:
Jörn-Hendrik Weitkamp, Jeffrey B. Brown, Zheng Zhang, Shirley X.L. Liu, Isabelle G. De Plaen, Terrence A. Barrett, Michael A. Helmrath, Valeria C. Cohran, Emily M. Bradford, Jennifer Hawkins, Paul Cheresh, Elizabeth Managlia, Rebecca B. Katzman, Tatiana Goretsky, Ting Li
Publikováno v:
The American Journal of Pathology. 186:1837-1846
Intestinal adaptation to small-bowel resection (SBR) after necrotizing enterocolitis expands absorptive surface areas and promotes enteral autonomy. Survivin increases proliferation and blunts apoptosis. The current study examines survivin in intesti
Autor:
Tianyan Gao, Preetika Sinh, Olivia F. Lamping, Tatiana Goretsky, Linheng Li, Qing-Bai She, Terrence A. Barrett, Qing Ye, Emily M. Bradford, Josep M. Llovet, Patrick C. Keller, Tomas Vanagunas, Mary Pat Moyer
Publikováno v:
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Nuclear activation of Wnt/β-catenin signaling is required for cell proliferation in inflammation and cancer. Studies from our group indicate that β-catenin activation in colitis and colorectal cancer (CRC) correlates with increased nuclear levels o
Publikováno v:
Journal of Clinical and Translational Science. 1:61-62
OBJECTIVES/SPECIFIC AIMS: Intestinal stem cells (ISC) primarily act in the repair of ulcerated epithelium, and their proliferative capacity relies on Wnt/β-catenin signaling. However, the role of GCs on basal epithelial cell signaling has not been f
Autor:
Alistair J. M. Watson, Jerrold R. Turner, Le Shen, Emily M. Bradford, Marshall H. Montrose, Amanda M. Marchiando, Yanfang Guan
Publikováno v:
American Journal of Physiology-Cell Physiology. 300:C1404-C1414
We questioned how tight junctions contribute to intestinal barrier function during the cell shedding that is part of physiological cell renewal. Intravital confocal microscopy studied the jejunal villus epithelium of mice expressing a fluorescent zon