Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emily M. Anderson"'
Publikováno v:
Geriatrics, Vol 3, Iss 3, p 49 (2018)
(1) Background: Studies have shown that older people prefer to continue living in their own home and community as they age; however this is dependent upon available services and social support. In Australia about two thirds of people will age at home
Externí odkaz:
https://doaj.org/article/3e92ed6a33a14148b8bc907b75f5c015
Autor:
Galen W. Miller, Kevin Hemphill, Maren M. Gross, Matthew R. Perkett, Elena Maksimova, Žaklina Strezoska, Eldon T. Chou, Travis Hardcastle, Annaleen Vermeulen, Anja van Brabant Smith, Sarah Michelle Dickerson, Jesse Stombaugh, Emily M. Anderson
Publikováno v:
Journal of Biotechnology. 319:25-35
The CRISPR-Cas9 system has been adapted for transcriptional activation (CRISPRa) and several second-generation CRISPRa systems (including VPR, SunTag, and SAM) have been developed to recruit different transcriptional activators to a deactivated Cas9,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3b357d21e6ea1ef50942e6dac1163e
https://doi.org/10.1016/j.jbiotec.2020.05.005
https://doi.org/10.1016/j.jbiotec.2020.05.005
Autor:
John A. Schiel, Zhenyi Liu, Angela Bartels, Guojun Zhao, Žaklina Strezoska, Elena Maksimova, Anja van Brabant Smith, Emily M. Anderson, Joe Warren, Yumei Wu, Kevin P. Forbes, Chris E. Lowe
Publikováno v:
The CRISPR Journal
MAD7 is an engineered class 2 type V-A CRISPR-Cas (Cas12a/Cpf1) system isolated from Eubacterium rectale. Analogous to Cas9, it is an RNA-guided nuclease with demonstrated gene editing activity in Escherichia coli and yeast cells. Here, we report tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38d376eebe93a1046f2247df725f664
https://doi.org/10.1089/crispr.2019.0068
https://doi.org/10.1089/crispr.2019.0068
Autor:
Žaklina Strezoska, Elena Maksimova, Annaleen Vermeulen, Shawn McClelland, Eldon T. Chou, Matthew R. Perkett, Anja van Brabant Smith, Emily M. Anderson, Melissa L. Kelley
Publikováno v:
Journal of Biotechnology. 251:189-200
The CRISPR-Cas9 system has been utilized for large-scale, loss-of-function screens mainly using lentiviral pooled formats and cell-survival phenotypic assays. Screening in an arrayed format expands the types of phenotypic readouts that can be used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f27c5e36515988cab627372f9ff388a
https://doi.org/10.1016/j.jbiotec.2017.04.017
https://doi.org/10.1016/j.jbiotec.2017.04.017
Autor:
Elena Maksimova, Shawn McClelland, Anja van Brabant Smith, Žaklina Strezoska, Rodolphe Barrangou, Alexandra E. Briner, Megan Basila, Emily M. Anderson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192181 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192181 (2018)
While the CRISPR-Cas9 system from S. pyogenes is a powerful genome engineering tool, additional programmed nucleases would enable added flexibility in targeting space and multiplexing. Here, we characterized a CRISPR-Cas9 system from L. gasseri and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b4c9c54569af9a471ad04f5a409ca4
http://europepmc.org/articles/PMC5796720
http://europepmc.org/articles/PMC5796720
Autor:
Gediminas Alzbutas, Emily M. Anderson, Arvydas Lubys, Lolita Zaliauskiene, Monika Glemzaite, Aiste Jurcyte, Anja Smith, Elena Maksimova, Virginijus Siksnys, Mantvyda M. Grusyte, Egle Balciunaite, Tautvydas Karvelis, Giedrius Gasiunas
Publikováno v:
RNA Biology
RNA biology, Philadelphia : Taylor & Francis Inc., 2015, vol. 12, no. 1, p. 1-4
RNA biology, Philadelphia : Taylor & Francis Inc., 2015, vol. 12, no. 1, p. 1-4
Cas9 protein of the Type II CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated)1 bacterial adaptive immune system emerged recently as a promising tool for genom...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9597cae1ab04120ac566bbca593b4555
http://europepmc.org/articles/PMC4615908
http://europepmc.org/articles/PMC4615908
Publikováno v:
Chembiochem
The CRISPR‐Cas9 gene editing system requires Cas9 endonuclease and guide RNAs (either the natural dual RNA consisting of crRNA and tracrRNA or a chimeric single guide RNA) that direct site‐specific double‐stranded DNA cleavage. This communicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c07a12f7d0a2b4ec5cb74b1c10c1fc7
https://pubmed.ncbi.nlm.nih.gov/27441384
https://pubmed.ncbi.nlm.nih.gov/27441384
Publikováno v:
Oncogene
Over two-thirds of melanomas have activating mutations in B-Raf, leading to constitutive activation of the B-Raf/MKK/ERK signaling pathway. The most prevalent mutation, B-RafV600E, promotes cancer cell behavior through mechanisms that are still incom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddaa987906a91abc24b0846def7b8c7
https://doi.org/10.1038/onc.2012.209
https://doi.org/10.1038/onc.2012.209
Publikováno v:
Advanced Emergency Nursing Journal. 30:209-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff2b5d80e11f39a3073ee2f4af4d4294
https://doi.org/10.1097/01.tme.0000334372.59776.93
https://doi.org/10.1097/01.tme.0000334372.59776.93
Autor:
Queta Boese, Angela Reynolds, Anastasia Khvorova, Devin Leake, Kevin Sullivan, Amanda Birmingham, Emily M. Anderson, Jon Karpilow
Publikováno v:
Nature Protocols. 2:2068-2078
Effective gene silencing by the RNA interference (RNAi) pathway requires a comprehensive understanding of the elements that influence small interfering RNA (siRNA) functionality and specificity. These include (i) sequence space restrictions that defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8829daa5c00baf639c25f5a61cff3f92
https://doi.org/10.1038/nprot.2007.278
https://doi.org/10.1038/nprot.2007.278