Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emily M Schneider"'
Autor:
Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker, Emily A. Kessler, Audrey J. Muscato, Arnav Mehta, Samuel S. Freeman, Peter M. Allen, Kira E. Olander, Kyle M. Ockerman, Clara H. Wolfe, Fabius Wiesmann, Nelson H. Knudsen, Hsiao-Wei Tsao, Arvin Iracheta-Vellve, Emily M. Schneider, Andrea N. Rivera-Rosario, Ian C. Kohnle, Hans W. Pope, Austin Ayer, Gargi Mishra, Margaret D. Zimmer, Sarah Y. Kim, Animesh Mahapatra, Hakimeh Ebrahimi-Nik, Dennie T. Frederick, Genevieve M. Boland, W. Nicholas Haining, David E. Root, John G. Doench, Nir Hacohen, Kathleen B. Yates, Robert T. Manguso
Publikováno v:
Nature immunology. 23(10)
The immune system can eliminate tumors, but checkpoints enable immune escape. Here, we identify immune evasion mechanisms using genome-scale in vivo CRISPR screens across cancer models treated with immune checkpoint blockade (ICB). We identify immune
Autor:
Susan Klaeger, John G. Doench, Jingyi Wu, Aya G Halawi, Emily M Schneider, Brian C. Miller, Emily J. Robitschek, Bradley E. Bernstein, Malvina Papanastasiou, Nelson H. Knudsen, Tung H Nguyen, Deborah Dele-Oni, Mitchell D Yeary, Kira E Olander, Kathleen B. Yates, James C Patti, Thomas Davis, Suzanna Rachimi, Robert T. Manguso, Jacob D. Jaffe, Gabriel K. Griffin, Jeffrey J. Ishizuka, W. Nicholas Haining, Jeffrey Hsu, Arvin Iracheta-Vellve, Steven A. Carr, Peter P. Du, Sarah Y Kim, Margaret D. Zimmer
Publikováno v:
Nature
Epigenetic dysregulation is a defining feature of tumorigenesis that is implicated in immune escape1,2. Here, to identify factors that modulate the immune sensitivity of cancer cells, we performed in vivo CRISPR-Cas9 screens targeting 936 chromatin r
Publikováno v:
Cement and Concrete Composites. 87:1-9
Each year, corrosion of concrete results in billions of dollars' worth in damage. Cinnamaldehyde, a bioactive agent, can mitigate the corrosion of metals and potentially protect rebar within concrete. However, it cannot be incorporated into concrete
Autor:
Emily J. Robitschek, Peter P. Du, Nelson H. Knudsen, Sarah Kim, Arvin Iracheta-Vellve, Robert T. Manguso, W. Nicholas Haining, Kathleen B. Yates, Jacob D. Jaffe, Jeffrey J. Ishizuka, Margaret D. Zimmer, Tung H Nguyen, Jingyi Wu, Emily M Schneider, Deborah Dele-Oni, John G. Doench, Susan Klaeger, Brian C. Miller, Gabriel K. Griffin, Jeffrey Hsu, James C Patti, Thomas Davis, Bradley E. Bernstein
Publikováno v:
Cancer Immunology Research. 9:PO009-PO009
Epigenetic alterations are defining features of many tumor types and have recently been implicated in tumor immunity. However, the epigenetic mechanisms that mediate immune sensitivity or resistance in cancer cells are poorly characterized. To system