Radiosynthesis and initial preclinical evaluation of [11C]AZD1283 as a potential P2Y12R PET radiotracer

Autor: Isaac M. Jackson, Pablo J. Buccino, E. Carmen Azevedo, Mackenzie L. Carlson, Audrey S.Z. Luo, Emily M. Deal, Mausam Kalita, Samantha T. Reyes, Xia Shao, Corinne Beinat, Sydney C. Nagy, Aisling M. Chaney, David A. Anders, Peter J.H. Scott, Mark Smith, Bin Shen, Michelle L. James

Publikováno v: Nuclear Medicine and Biology. :143-150

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::620fc3b36a6c12fd29c13b8817aa46f5
https://doi.org/10.1016/j.nucmedbio.2022.05.001

Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Autor: Thomas Sharpton, Svetlana Lyalina, Julie Luong, Joey Pham, Emily M. Deal, Courtney Armour, Christopher Gaulke, Shomyseh Sanjabi, Katherine S. Pollard

Publikováno v: mSystems, Vol 2, Iss 5 (2017)

ABSTRACT The gut microbiome is linked to inflammatory bowel disease (IBD) severity and altered in late-stage disease. However, it is unclear how gut microbial communities change over the course of IBD development, especially in regard to function. To

Externí odkaz: https://doaj.org/article/2dc46ba55ca047c98562fdedba938cd8

Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Autor: Katherine S. Pollard, Emily M. Deal, Julie Luong, Christopher A. Gaulke, Courtney R. Armour, Joey Pham, Svetlana Lyalina, Thomas J. Sharpton, Shomyseh Sanjabi

Publikováno v: mSystems, vol 2, iss 5
mSystems, Vol 2, Iss 5 (2017)
Sharpton, T; Lyalina, S; Luong, J; Pham, J; Deal, EM; Armour, C; et al.(2017). Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice. MSYSTEMS, 2(5). doi: 10.1128/mSystems.00036-17. UCSF: Retrieved from: http://www.escholarship.org/uc/item/0zd6f6rk
mSystems, Vol 2, Iss 5, p e00036-17 (2017)
mSystems

IBD patients harbor distinct microbial communities with functional capabilities different from those seen with healthy people. But is this cause or effect? Answering this question requires data on changes in gut microbial communities leading to disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12630d2cc73e8968eb048c03379845e9
https://escholarship.org/uc/item/0zd6f6rk

Rhesus Rotavirus Trafficking during Entry into MA104 Cells Is Restricted to the Early Endosome Compartment

Autor: Marie Wolf, Emily M. Deal, Harry B. Greenberg

Publikováno v: Journal of Virology. 86:4009-4013

Endocytosis has recently been implicated in rotavirus (RV) entry. We examined the role of Rabs, which regulate endosomal trafficking, during RV entry. Several structural proteins of neuraminidase-sensitive and -insensitive RVs colocalized with Rab5,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d681131b160cff6356f4bbde3d022e
https://doi.org/10.1128/jvi.06667-11

Ebola virus-like particles protect from lethal Ebola virus infection

Autor: Emily M. Deal, Kelly L. Warfield, M. Javad Aman, Sina Bavari, Mansour Mohamadzadeh, Catharine M. Bosio, Brent C. Welcher, Alan L. Schmaljohn

Publikováno v: Proceedings of the National Academy of Sciences. 100:15889-15894

The filovirus Ebola causes hemorrhagic fever with 70–80% human mortality. High case-fatality rates, as well as known aerosol infectivity, make Ebola virus a potential global health threat and possible biological warfare agent. Development of an eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6e0832e570e8beac2a92c6d6964235
https://doi.org/10.1073/pnas.2237038100