Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily M, Schulz"'
Autor:
Emily M. Schulz, David F. Wieczorek
Publikováno v:
Journal of Muscle Research and Cell Motility. 34:239-246
The focus of this review is on the very recent work we have conducted that addresses the molecular, morphological, and physiological significance of cardiac tropomyosin phosphorylation in the heart. We employ transgenic mice to address questions of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2ec88ff78c6523996c3764f2d63d7f
https://doi.org/10.1007/s10974-013-9348-7
https://doi.org/10.1007/s10974-013-9348-7
Publikováno v:
European Journal of Neuroscience. 26:3104-3112
A key challenge in Parkinson's disease research is to understand mechanisms underlying selective degeneration of dopaminergic neurons mediated by genetic factors such as alpha-synuclein (alpha-Syn). The present study examined whether dopamine (DA)-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c557c4ea3e023e37b5def534492a0e8
https://doi.org/10.1111/j.1460-9568.2007.05929.x
https://doi.org/10.1111/j.1460-9568.2007.05929.x
Autor:
Emily M Schulz, Allison E Dixon, Michael S Burhans, Michelle L Nieman, John N Lorenz, Val Goodfellow, Harris A Gelbard, Stephen Dewhurst, Burns C Blaxall
Publikováno v:
Circulation Research. 115
Mixed lineage kinase 3 (MLK3) is a ubiquitously expressed pro-inflammatory, pro-apoptotic mitogen activated protein kinase kinase kinase (MAP3K). MLK3 is a key regulator of the p38 and c-jun terminal kinase (JNK) pathways and has been studied in canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c8ba8f1380c541d2bc2a4dca7fb751
https://doi.org/10.1161/res.115.suppl_1.315
https://doi.org/10.1161/res.115.suppl_1.315
Autor:
Emily M. Schulz, Shamim A. K. Chowdhury, R. John Solaro, Beata M. Wolska, Hajer N. Sheikh, Tanganyika Wilder, David F. Wieczorek
Publikováno v:
The Journal of biological chemistry. 288(40)
Background: Increased calcium uptake can rescue congenital cardiomyopathies. Results: Decreasing tropomyosin phosphorylation increases phospholamban phosphorylation and improves cardiac function and morphology in a cardiomyopathic mouse. Conclusion:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2d5c543f901adc067a29870acac874
https://pubmed.ncbi.nlm.nih.gov/23960072
https://pubmed.ncbi.nlm.nih.gov/23960072
Autor:
Bruns C Blaxall, Stephen Dewhurst, Melissa L. Martin, Harris A. Gelbard, Emily M Schulz, Val S. Goodfellow
Publikováno v:
Circulation Research. 113
Cardiovascular disease (CVD) and the final clinical iteration, heart failure (HF), affect more than 82 million Americans yearly, affects >5.7 million). Although the cardiac myocyte has long been the focus of cardiac cellular research, our lab and oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::717aaedfb845585007094953c311402b
https://doi.org/10.1161/res.113.suppl_1.a301
https://doi.org/10.1161/res.113.suppl_1.a301
Autor:
Jeffery D. Molkentin, Beata M. Wolska, Hajer N. Sheikh, R. John Solaro, Jo El J. Schultz, Patti L. Engel, Emily M. Schulz, Marcos S. Lofrano-Alves, David F. Wieczorek, Gilbert Newman, Richard N.. Correll
Phosphorylation of tropomyosin (Tm) has been shown to vary in mouse models of cardiac hypertrophy. Little is known about the in vivo role of Tm phosphorylation. This study examines the consequences of Tm dephosphorylation in the murine heart. Transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fc234909cc67c98c82124938f2fdc8
https://europepmc.org/articles/PMC3531761/
https://europepmc.org/articles/PMC3531761/
Autor:
R. John Solaro, Rafeeq P.H. Ahmed, Ganapathy Jagatheesan, Tao Wang, Muhammad Ashraf, Natalia Petrashevskaya, David F. Wieczorek, Greg P. Boivin, Yigang Wang, Grace M. Arteaga, John N. Lorenz, Stephen B. Liggett, Emily M. Schulz, Arnold Schwartz, Sudarsan Rajan
Tropomyosin (TM) is involved in Ca2+-mediated muscle contraction and relaxation in the heart. Striated muscle α-TM is the major isoform expressed in the heart. The expression of striated muscle β-TM in the murine myocardium results in a decreased r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79990dd0890be90a0c167777e29c329a
https://europepmc.org/articles/PMC2711731/
https://europepmc.org/articles/PMC2711731/
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein
Publikováno v:
The European journal of neuroscience. 26(11)
A key challenge in Parkinson's disease research is to understand mechanisms underlying selective degeneration of dopaminergic neurons mediated by genetic factors such as alpha-synuclein (alpha-Syn). The present study examined whether dopamine (DA)-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbc9f781a1a7efb5fb7caeff5cf14b0f
https://pubmed.ncbi.nlm.nih.gov/18005066
https://pubmed.ncbi.nlm.nih.gov/18005066
Autor:
Arnold Schwartz, Ganapathy Jagatheesan, R. John Solaro, David F. Wieczorek, Emily M. Schulz, Natalia Petrashevskaya, Rafeeq P.H. Ahmed, Stephen B. Liggett, Grace M. Arteaga, Gregory P. Boivin
Publikováno v:
Biophysical Journal. 96:504a
Table of ContentsTropomyosin (TM) is involved in calcium mediated muscle contraction and relaxation in the heart. Striated muscle alpha TM is the major isoform expressed in the heart. Expression of striated muscle beta TM in murine myocardium results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c010660aa21193c5b9a8f1b66ed6c50a
https://doi.org/10.1016/j.bpj.2008.12.2597
https://doi.org/10.1016/j.bpj.2008.12.2597