Zobrazeno 1 - 10 of 29 pro vyhledávání: '"Emily Levy"'
1
Akademický článek
Redirecting NK cells to the lymph nodes to augment their lymphoma-targeting capacity
Autor: Laura Sanz-Ortega, Caroline Leijonhufvud, Lisanne Schoutens, Mélanie Lambert, Emily Levy, Agneta Andersson, Björn E. Wahlin, Mattias Carlsten
Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract CAR-NK cells can induce remission in lymphoma patients. We speculate that the full potential of adoptive NK cell immunotherapy against lymphoma is restricted by their poor lymph node (LN) homing capacity. Here, we have utilized a clinically
Externí odkaz: https://doaj.org/article/7acccb198f3946cc85feef06f411ad75
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2
Akademický článek
B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells
Autor: Liam J. Dwyer, Saumya Maheshwari, Emily Levy, Mark C. Poznansky, Michael J. Whalen, Ruxandra F. Sîrbulescu
Publikováno v: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Traumatic brain injury (TBI) remains a major cause of death and severe disability worldwide. We found previously that treatment with exogenous naïve B cells was associated with structural and functional neuroprotection after TBI. Here, we u
Externí odkaz: https://doaj.org/article/e5397a7437654fecb3bcdfefe1cd6bca
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3
Akademický článek
Localization of Multi-Lamellar Vesicle Nanoparticles to Injured Brain Tissue in a Controlled Cortical Impact Injury Model of Traumatic Brain Injury in Rodents
Autor: Ricky Whitener, Jeremy J. Henchir, Thomas A. Miller, Emily Levy, Aubrienne Krysiewicz-Bell, Eliza S. LaRovere Abrams, Shaun W. Carlson, Naresh Menon, C. Edward Dixon, Michael J. Whalen, Claude J. Rogers
Publikováno v: Neurotrauma Reports, Vol 3, Iss 1, Pp 158-167 (2022)
Severe traumatic brain injury (TBI), such as that suffered by patients with cerebral contusion, is a major cause of death and disability in young persons. Effective therapeutics to treat or mitigate the effects of severe TBI are lacking, in part beca
Externí odkaz: https://doaj.org/article/34d7cea5ed5541d494f13ceecb9da5a1
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5
Akademický článek
Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X
Autor: Emily Levy, Robert Reger, Filip Segerberg, Melanie Lambert, Caroline Leijonhufvud, Yvonne Baumer, Mattias Carlsten, Richard Childs
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Adoptive transfer of natural killer (NK) cells can induce remission in patients with relapsed/refractory leukemia and myeloma. However, to date, clinical efficacy of NK cell immunotherapy has been limited to a sub-fraction of patients. Here we show t
Externí odkaz: https://doaj.org/article/19f9b32dc57341019ce2e9a6197cac09
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6
Akademický článek
Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5
Autor: Mattias Carlsten, Ali Namazi, Robert Reger, Emily Levy, Maria Berg, Cynthia St. Hilaire, Richard W. Childs
Publikováno v: OncoImmunology, Vol 8, Iss 2 (2019)
Although the proteasome inhibitor bortezomib has significantly improved the survival of patients with multiple myeloma (MM), the disease remains fatal as most patients eventually develop progressive disease. Recent data indicate that MM cells can eva
Externí odkaz: https://doaj.org/article/3e8048744d0b4ef1919bf2de92ce2ec8
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7
Akademický článek
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