The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccineesResearch in context

Autor: Julie Van Coillie, Tamas Pongracz, Johann Rahmöller, Hung-Jen Chen, Chiara Elisabeth Geyer, Lonneke A. van Vught, Jana Sophia Buhre, Tonći Šuštić, Thijs Luc Junior van Osch, Maurice Steenhuis, Willianne Hoepel, Wenjun Wang, Anne Sophie Lixenfeld, Jan Nouta, Sofie Keijzer, Federica Linty, Remco Visser, Mads Delbo Larsen, Emily Lara Martin, Inga Künsting, Selina Lehrian, Vera von Kopylow, Carsten Kern, Hanna Bele Lunding, Menno de Winther, Niels van Mourik, Theo Rispens, Tobias Graf, Marleen Adriana Slim, René Peter Minnaar, Marije Kristianne Bomers, Jonne Jochum Sikkens, Alexander P.J. Vlaar, C. Ellen van der Schoot, Jeroen den Dunnen, Manfred Wuhrer, Marc Ehlers, Gestur Vidarsson, Spinello Antinori, Cinzia Bassoli, Giovanna Bestetti, Mario Corbellino, Alice Covizzi, Angelica Lupo, Laura Milazzo, Marco Schiuma, Alessandro Torre, Brent Appelman, Diederik Beek van de, Marije K. Bomers, Justin Brabander de, Matthijs C. Brouwer, David T.P. Buis, Nora Chekrouni, Marit J. Gils van, Menno D. Jong de, Ayesha H.A. Lavell, Niels Mourik van, Sabine E. Olie, Edgar J.G. Peters, Tom D.Y. Reijnders, Michiel Schinkel, Alex R. Schuurman, Jonne J. Sikkens, Marleen A. Slim, Yvo M. Smulders, Lonneke A. Vught van, Joost W. Wiersinga

Publikováno v: EBioMedicine, Vol 87, Iss , Pp 104408- (2023)

Summary: Background: Afucosylated IgG1 responses have only been found against membrane-embedded epitopes, including anti-S in SARS-CoV-2 infections. These responses, intrinsically protective through enhanced FcγRIIIa binding, can also trigger exacer

Externí odkaz: https://doaj.org/article/bd40a551975d4a2c9340f940154e729f

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

Autor: Antinori, Spinello, Bassoli, Cinzia, Bestetti, Giovanna, Corbellino, Mario, Covizzi, Alice, Lupo, Angelica, Milazzo, Laura, Schiuma, Marco, Torre, Alessandro, Appelman, Brent, van de Beek, Diederik, Bomers, Marije K., de Brabander, Justin, Brouwer, Matthijs C., Buis, David T.P., Chekrouni, Nora, van Gils, Marit J., de Jong, Menno D., Lavell, Ayesha H.A., van Mourik, Niels, Olie, Sabine E., Peters, Edgar J.G., Reijnders, Tom D.Y., Schinkel, Michiel, Schuurman, Alex R., Sikkens, Jonne J., Slim, Marleen A., Smulders, Yvo M., Vlaar, Alexander P.J., van Vught, Lonneke A., Wiersinga, Joost W., Van Coillie, Julie, Pongracz, Tamas, Rahmöller, Johann, Chen, Hung-Jen, Geyer, Chiara Elisabeth, Buhre, Jana Sophia, Šuštić, Tonći, van Osch, Thijs Luc Junior, Steenhuis, Maurice, Hoepel, Willianne, Wang, Wenjun, Lixenfeld, Anne Sophie, Nouta, Jan, Keijzer, Sofie, Linty, Federica, Visser, Remco, Larsen, Mads Delbo, Martin, Emily Lara, Künsting, Inga, Lehrian, Selina, von Kopylow, Vera, Kern, Carsten, Lunding, Hanna Bele, de Winther, Menno, Rispens, Theo, Graf, Tobias, Slim, Marleen Adriana, Minnaar, René Peter, Bomers, Marije Kristianne, Sikkens, Jonne Jochum, van der Schoot, C. Ellen, den Dunnen, Jeroen, Wuhrer, Manfred, Ehlers, Marc, Vidarsson, Gestur

Publikováno v: In eBioMedicine January 2023 87

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

Autor: Julie Van Coillie, Tamas Pongracz, Johann Rahmöller, Hung-Jen Chen, Chiara Elisabeth Geyer, Lonneke A. van Vught, Jana Sophia Buhre, Tonći Šuštić, Thijs Luc Junior van Osch, Maurice Steenhuis, Willianne Hoepel, Wenjun Wang, Anne Sophie Lixenfeld, Jan Nouta, Sofie Keijzer, Federica Linty, Remco Visser, Mads Delbo Larsen, Emily Lara Martin, Inga Künsting, Selina Lehrian, Vera von Kopylow, Carsten Kern, Hanna Bele Lunding, Menno de Winther, Niels van Mourik, Theo Rispens, Tobias Graf, Marleen Adriana Slim, René Peter Minnaar, Marije Kristianne Bomers, Jonne Jochum Sikkens, Alexander P.J. Vlaar, C. Ellen van der Schoot, Jeroen den Dunnen, Manfred Wuhrer, Marc Ehlers, Gestur Vidarsson, Spinello Antinori, Cinzia Bassoli, Giovanna Bestetti, Mario Corbellino, Alice Covizzi, Angelica Lupo, Laura Milazzo, Marco Schiuma, Alessandro Torre, Brent Appelman, Diederik van de Beek, Marije K. Bomers, Justin de Brabander, Matthijs C. Brouwer, David T.P. Buis, Nora Chekrouni, Marit J. van Gils, Menno D. de Jong, Ayesha H.A. Lavell, Sabine E. Olie, Edgar J.G. Peters, Tom D.Y. Reijnders, Michiel Schinkel, Alex R. Schuurman, Jonne J. Sikkens, Marleen A. Slim, Yvo M. Smulders, Joost W. Wiersinga

Publikováno v: EBioMedicine, 87:104408. Elsevier BV
EBioMedicine, 87. Elsevier BV
Fatebenefratelli-Sacco Infectious Diseases Physicians group & UMC COVID-19 S3/HCW study group 2023, ' The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees ', EBioMedicine, vol. 87, 104408 . https://doi.org/10.1016/j.ebiom.2022.104408
EBioMedicine, 87. ELSEVIER

Background: Afucosylated IgG1 responses have only been found against membrane-embedded epitopes, including anti-S in SARS-CoV-2 infections. These responses, intrinsically protective through enhanced Fc gamma RIIIa binding, can also trigger exacerbate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fcb2d4fcdef047f32eab27f86987dc
https://doi.org/10.1016/j.ebiom.2022.104408

Correction to Supporting Information for Suzuki et al., Behavioral contagion during learning about another agent’s risk-preferences acts on the neural representation of decision-risk

Autor: Emily Lara Dawra

Publikováno v: Proceedings of the National Academy of Sciences. 114

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a6169d94c4ac5a3b74c22d6e12dec45
https://doi.org/10.1073/pnas.1708546114