Comparative analysis of astrocytes in the prefrontal cortex of primates: Insights into the evolution of human brain energetics

Autor: Emily L. Munger, Melissa K. Edler, William D. Hopkins, Patrick R. Hof, Chet C. Sherwood, Mary Ann Raghanti

Publikováno v: The Journal of comparative neurology. 530(18)

Astrocytes are the main homeostatic cell of the brain involved in many processes related to cognition, immune response, and energy expenditure. It has been suggested that the distribution of astrocytes is associated with brain size, and that they are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c470d9ccc1063a6401823e962b22dd
https://pubmed.ncbi.nlm.nih.gov/35859531

Contributors

Autor: Michelle M. Adams, Cédric Albinet, Banu Alicioglu, Paolo Amami, Nathalie André, Narin Ilgim Ardic-Avci, Elizabeth Arslanoglou, Guilherme Giannini Artioli, Michel Audiffren, Hande Ozge Aydogan, Francisco Javier Belchí, Marvin H. Berman, Ondrej Bezdicek, Cynthia Bianco, Jasmina Boban, Carlos Roberto Bueno Júnior, Blake E. Butler, Daniele Cartelli, Augusto Pietro Casani, Dilan Celebi-Birand, Zikuan Chen, Zeyuan Chen, Bihong T. Chen, Katie E. Cherry, Christian Chicherio, Jeshya A. Chio, Pere Clavé, Victoria C. Cogger, Márcia Regina Cominetti, Ma Fe P. de Guzman, Maria Clarissa O. del Moral, Eimear Dolan, Jacqueline C. Dominguez, Premchand Dommaraju, Theresa Ebo, Melissa K. Edler, Begun Erbaba, Ghazaleh Eskandari-Sedighi, Delphine Fagot, Fereshteh Farajdokht, Isabel Fariñas, Laís Francielle Francisca Felício, Luiz Felipe da Silva Figueiredo, Karen L. Fortuna, Máximo Ibo Galindo, Ekavi N. Georgousopoulou, Rahul Gokarn, Gabriel Gold, Hayley Groetz, Bruno Gualano, G.M. Halliday, Erin E. Harrington, Claudia Heidenreich, Boris Henčić, Rafael Hernández, Björn Herrmann, Jasna Jančić, R.C. Jeżewski, Hulusi Kafaligonul, Hakki Muammer Karakas, Elif Tugce Karoglu-Eravsar, Dimitris Kiosses, Dusko Kozic, Enikö Kövari, Lewis H. Kuller, Thomas J. LaRocca, David G. Le Couteur, Gary Jek Chong Lee, Unax Lertxundi, Víctor López del Amo, Mariana Luciano de Almeida, Javad Mahmoudi, João O. Malva, Patricia Regina Manzine, Beatriz Martins, Douglas B. Matthews, Derval McCormack, Juan Medrano, Duane D. Mellor, Juan C. Meléndez, Jonas Mengel-From, Jelena Milić, Jody Monkovic, Renato Sobral Monteiro-Junior, Ricardo Moreira, Emily L. Munger, Elena Navari, M. Christopher Newland, João Novo, Reinaldo B. Oriá, Fiadhnait O’Keeffe, Demosthenes B. Panagiotakos, Frederico C. Pereira, Ana Perez-Villalba, Rafaela Peron, Victor R. Preedy, Mary Ann Raghanti, Simona Raimo, Rajkumar Rajendram, Ana López Ramírez, Ramon Raposo, David Raubenheimer, Punam Rawal, Celinda Reese-Melancon, Hannah Reich, Carmen Requena, Carlos Fontes Ribeiro, Ana Carolina de Mello Alves Rodrigues, Luis Miguel Rondón García, Rosa Raquel Ruiz Trascastro, Saeed Sadigh-Eteghad, Farzad Salehpour, Janko Samardžić, Gabriella Santangelo, Encarnación Satorres, Andrew N. Shen, C.E. Shepherd, Stephen J. Simpson, Marina Yazigi Solis, Samantha M. Solon-Biet, Dunja Stankić, Timo E. Strandberg, Astrid M. Suchy-Dicey, Andrea Tapia, Majda M. Thurnher, Paula Álvarez-Merino, Noemí Tomsen, Luigi Trojano, Melek Umay Tuz-Sasik, Henryk F. Urbanski, Rodrigo Portes Ureshino, Ed van Beeck, Candice E. Van Skike, Izabela Pereira Vatanabe, Devin Wahl, David Westaway, Shawn Wong, Long Wu, Túlio Brandão Xavier-Rocha, Janko Zeković, Xin Zhang, Liqin Zhao

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29030ec9d0d9b573eaa7429179db2306
https://doi.org/10.1016/b978-0-12-818000-6.01002-7

Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain

Autor: Melissa K. Edler, Elliott J. Mufson, Patrick R. Hof, Chet C. Sherwood, Richard S. Meindl, Joseph M. Erwin, Mary Ann Raghanti, John J. Ely, William D. Hopkins, Emily L. Munger

Publikováno v: Philos Trans R Soc Lond B Biol Sci

In the absence of disease, ageing in the human brain is accompanied by mild cognitive dysfunction, gradual volumetric atrophy, a lack of significant cell loss, moderate neuroinflammation, and an increase in the amyloid beta (A β ) and tau proteins.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775fa86649a57847bc40f97d249717a1
https://pubmed.ncbi.nlm.nih.gov/32951541

Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees

Autor: Melissa K. Edler, Daniel P. Perl, Mary Ann Raghanti, John J. Ely, Elliott J. Mufson, Chet C. Sherwood, William D. Hopkins, Richard S. Meindl, Emily L. Munger, Patrick R. Hof, Joseph M. Erwin

In Alzheimer's disease (AD), the brain's primary immune cells, microglia, become activated and are found in close apposition to amyloid beta (Aβ) protein plaques and neurofibrillary tangles (NFT). The present study evaluated microglia density and mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c96c5caca6b00167ccb409c4bf3f75
https://europepmc.org/articles/PMC6283685/

A neurochemical hypothesis for the origin of hominids

Autor: Alexa R. Stephenson, Emily L. Munger, Chet C. Sherwood, Mary Ann Raghanti, Melissa K. Edler, Patrick R. Hof, C. Owen Lovejoy, Ralph L. Holloway, Bob Jacobs

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 115(6)

It has always been difficult to account for the evolution of certain human characters such as language, empathy, and altruism via individual reproductive success. However, the striatum, a subcortical region originally thought to be exclusively motor,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1bc30812fd88d1976fb162e7dfb5ba
https://pubmed.ncbi.nlm.nih.gov/29358369