Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emily L. Morton"'
Autor:
Emily L. Morton, Christian V. Forst, Yue Zheng, Ana B. DePaula-Silva, Nora-Guadalupe P. Ramirez, Vicente Planelles, Iván D’Orso
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 154-171.e9 (2019)
Summary: Transcriptional circuit architectures in several organisms have been evolutionarily selected to dictate precise given responses. Unlike these cellular systems, HIV is regulated through a complex circuit composed of two successive phases (hos
Externí odkaz:
https://doaj.org/article/22746d2d5a3f4811a3dc152cd17cabfe
Autor:
John A. Josey, Zhaodan Cao, Tai Wong, Megan M. Halfmann, Heli Huang, Barry Goggin, Robert M. Czerwinski, Hanbiao Yang, Paul M. Wehn, Bin Wang, Shanhai Xie, Sarah R. Olive, Huiling Tan, Eli M. Wallace, Darryl D. Dixon, Melissa A. Maddie, Xinlin Du, Rui Xu, Stephen T. Schlachter, James P. Rizzi, Emily L. Morton, Tzuling Cheng, Jonas Grina, Keshi Wang, Guangzhou Han
Publikováno v:
Journal of Medicinal Chemistry. 61:9691-9721
HIF-2α, a member of the HIF family of transcription factors, is a key oncogenic driver in cancers such as clear cell renal cell carcinoma (ccRCC). A signature feature of these cancers is the overaccumulation of HIF-2α protein, often by inactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf4fbb16ea14332bdd9c2e58a806b92
https://doi.org/10.1021/acs.jmedchem.8b01196
https://doi.org/10.1021/acs.jmedchem.8b01196
Autor:
Yue Zheng, Nora Guadalupe P. Ramirez, Vicente Planelles, Emily L. Morton, Ana Beatriz DePaula-Silva, Christian V. Forst, Iván D'Orso
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 154-171.e9 (2019)
SUMMARYTranscriptional circuit architectures can be evolutionarily selected to precisely dictate a given response. Unlike these cellular systems, HIV is regulated through a complex circuit composed of two successive phases (host and viral), which cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9c951deaff39e7942a5e5434375219
https://europepmc.org/articles/PMC6461408/
https://europepmc.org/articles/PMC6461408/
Autor:
Paul M, Wehn, James P, Rizzi, Darryl D, Dixon, Jonas A, Grina, Stephen T, Schlachter, Bin, Wang, Rui, Xu, Hanbiao, Yang, Xinlin, Du, Guangzhou, Han, Keshi, Wang, Zhaodan, Cao, Tzuling, Cheng, Robert M, Czerwinski, Barry S, Goggin, Heli, Huang, Megan M, Halfmann, Melissa A, Maddie, Emily L, Morton, Sarah R, Olive, Huiling, Tan, Shanhai, Xie, Tai, Wong, John A, Josey, Eli M, Wallace
Publikováno v:
Journal of medicinal chemistry. 61(21)
HIF-2α, a member of the HIF family of transcription factors, is a key oncogenic driver in cancers such as clear cell renal cell carcinoma (ccRCC). A signature feature of these cancers is the overaccumulation of HIF-2α protein, often by inactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a0d9ca94f8b248f10acd7cb52b365e8
https://pubmed.ncbi.nlm.nih.gov/30289716
https://pubmed.ncbi.nlm.nih.gov/30289716
Publikováno v:
Molecular and Cellular Biology. 35:3810-3828
Transcription elongation programs are vital for the precise regulation of several biological processes. One key regulator of such programs is the P-TEFb kinase, which phosphorylates RNA polymerase II (Pol II) once released from the inhibitory 7SK sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4974fb5b3f590c64fbf66a996525cfbf
https://doi.org/10.1128/mcb.00226-15
https://doi.org/10.1128/mcb.00226-15