Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emily L. Goldberg"'
Autor:
Takeshi Tsusaka, Juan A. Oses-Prieto, Christina Lee, Brian C. DeFelice, Alma L. Burlingame, Emily L. Goldberg
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107235- (2023)
Summary: Ketone bodies are short-chain fatty acids produced in the liver during periods of limited glucose availability that provide an alternative energy source for the brain, heart, and skeletal muscle. Beyond this metabolic role, β-hydroxybutyrat
Externí odkaz:
https://doaj.org/article/2f93bf1dffc04c3f838dc092a45f7ba9
Autor:
Emily L. Goldberg
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 93-95 (2020)
Inflammation is a broad term that refers to a collection of carefully balanced programs in the body. These pathways are essential for detecting invading microorganisms, controlling the spread of infection, and instructing appropriate immune responses
Externí odkaz:
https://doaj.org/article/d686e7d63d454a0a85d381552084b551
Autor:
Emily L. Goldberg, Jennifer L. Asher, Ryan D. Molony, Albert C. Shaw, Caroline J. Zeiss, Chao Wang, Ludmilla A. Morozova-Roche, Raimund I. Herzog, Akiko Iwasaki, Vishwa Deep Dixit
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2077-2087 (2017)
Summary: Aging and lipotoxicity are two major risk factors for gout that are linked by the activation of the NLRP3 inflammasome. Neutrophil-mediated production of interleukin-1β (IL-1β) drives gouty flares that cause joint destruction, intense pain
Externí odkaz:
https://doaj.org/article/ba5a00dc1cfc44ada190e57c986b318e
Autor:
Emily L. Goldberg, Vishwa Deep Dixit
Publikováno v:
Molecular Metabolism, Vol 6, Iss 2, Pp 219-225 (2017)
Objective: Fatty acid oxidation in macrophages is thought to regulate inflammatory status and insulin-sensitivity. An important unanswered question in this field is whether carnitine acetyl-transferase (CrAT) that regulates fatty acid oxidation and m
Externí odkaz:
https://doaj.org/article/f4bb84b89adf439ba0468044a2b85b94
Aging is accompanied by chronic low-grade inflammation, but the mechanisms that allow this to persist are not well understood. Ketone bodies are alternative fuels produced when glucose is limited and improve indicators of healthspan in aging mouse mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93384bcf16d9f1aa2f076676d0a17891
https://doi.org/10.1101/2022.10.14.512312
https://doi.org/10.1101/2022.10.14.512312
Autor:
Maxim N. Artyomov, Vishwa Deep Dixit, Jennifer L. Asher, Emily L. Goldberg, Sviatoslav Sidorov, Irina Shchukina
Publikováno v:
Nat Metab
Ketone bodies are essential alternative fuels that allow humans to survive periods of glucose scarcity induced by starvation and prolonged exercise. A widely used ketogenic diet (KD), which is extremely high in fat with very low carbohydrates, drives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70af42be1b13c1bef971c3628981b8c
https://doi.org/10.1038/s42255-019-0160-6
https://doi.org/10.1038/s42255-019-0160-6
Autor:
Abhishek Singh, Xinbo Zhang, Qian Li, Bonne M Thompson, Yajaira Suárez, Jeffrey G McDonald, Jose Ordovas-Montanes, Carlos Fernández-Hernando, Rolando García Milian, Wen Ding, Elisa Araldi, Alberto Canfrán-Duque, Binod Aryal, Emily L. Goldberg, Yuhua Fan, Vishwa Deep Dixit, George Tellides, Elina Ikonen
Publikováno v:
Proc Natl Acad Sci U S A
Cholesterol biosynthetic intermediates, such as lanosterol and desmosterol, are emergent immune regulators of macrophages in response to inflammatory stimuli or lipid overloading, respectively. However, the participation of these sterols in regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69643fea4521d726d39d4f01d304deca
https://doi.org/10.1073/pnas.2107682118
https://doi.org/10.1073/pnas.2107682118
Autor:
Vishwa Deep Dixit, Christina D. Camell, Takeshi Tsusaka, Tamara Dlugos, Irina Shchukina, Emily L. Goldberg, Seungjin Ryu, Maxim N. Artyomov, Kyrlia C. Young, Yun-Hee Youm
Publikováno v:
Cell metabolism, vol 33, iss 11
Cell Metab
Cell Metab
Aging impairs the integrated immunometabolic responses, which have evolved to maintain core body temperature in homeotherms to survive cold stress, infections, and dietary restriction. Adipose tissue inflammation regulates the thermogenic stress resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97f786065acea8e8ad0af3e44ae2af5
https://pubmed.ncbi.nlm.nih.gov/34545230
https://pubmed.ncbi.nlm.nih.gov/34545230
Autor:
Maxim N. Artyomov, Christina D. Camell, Tamara Dlugos, Irina Shchukina, Emily L. Goldberg, Yun-Hee Youm, Vishwa Deep Dixit
Aging impairs the integrated immunometabolic responses which have evolved to maintain core body temperature in homeotherms to survive cold-stress, infections, and dietary restriction. Adipose tissue inflammation regulates the thermogenic stress respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f85cdd07f77da9824b609a0e227256
https://doi.org/10.1101/2020.09.08.288431
https://doi.org/10.1101/2020.09.08.288431
Autor:
Emily L. Goldberg, Vishwa Deep Dixit
Publikováno v:
Cell Metabolism. 30:621-623
An integrated immunometabolic response during negative energy balance is required for host survival. Three new papers by Jordan et al. (2019), Nagai et al. (2019), and Collins et al. (2019) report that monocytes, naive B cells, and memory CD8 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10c32336bf3879a5297c375427bb712
https://doi.org/10.1016/j.cmet.2019.08.022
https://doi.org/10.1016/j.cmet.2019.08.022