Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates

Autor: Adam Nelson, Emily L Faulkner, Alexandre F. Trindade, Andrew G. Leach, Stephen P. Marsden

Publikováno v: Trindade, A F, Faulkner, E L, Leach, A G, Nelson, A & Marsden, S P 2020, ' Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates ', Chemical communications (Cambridge, England) . https://doi.org/10.1039/d0cc03934a

A strategy for the β-sp3 functionalisation of cyclic amines is described. Regioselective conversion of protected amines to enecarbamates is achieved through electrochemical oxidation; these intermediates can be derivatised by functionalised alkyl ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad2bef2bcb79e8570af07185529ce9a
https://doi.org/10.1039/d0cc03934a