Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Emily Kimmel"'
Autor:
Amanda Robison, Deann T Snyder, Kelly Christensen, Emily Kimmel, Adeline M Hajjar, Mark A Jutila, Jodi F Hedges
Publikováno v:
Innate Immunity, Vol 25 (2019)
Human TLR4 (hTLR4) and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated and heavily glycosylated and causes a minimal response by human cells. Thus, we hypothesized that mice expressing hTLR
Externí odkaz:
https://doaj.org/article/2436fc1d1db445079d033da85c9d3079
Autor:
Emily Kimmel, Deann T. Snyder, Kelly Christensen, Amanda Robison, Jodi F. Hedges, Adeline M. Hajjar, Mark A. Jutila
Publikováno v:
Innate Immunity, Vol 25 (2019)
Human TLR4 (hTLR4) and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated and heavily glycosylated and causes a minimal response by human cells. Thus, we hypothesized that mice expressing hTLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f56e642e03a916ab013de68de572ba
https://doaj.org/article/2436fc1d1db445079d033da85c9d3079
https://doaj.org/article/2436fc1d1db445079d033da85c9d3079
Autor:
Sharon Kemoli, Jodi F. Hedges, Jeff Holderness, Emily Kimmel, Mark A. Jutila, Deann T. Snyder, Amanda Robison
Publikováno v:
Journal of Leukocyte Biology. 95:841-847
Type I IFN signaling is a central pathway that provides critical innate protection from viral and bacterial infection and can have regulatory outcomes in inflammatory settings. We determined previously that OPCs contained in the dietary supplement AP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d16b215ee246d1b1935bde485ec6574
https://doi.org/10.1189/jlb.0513296
https://doi.org/10.1189/jlb.0513296
Publikováno v:
The Journal of Immunology. 190:4263-4273
Solute carrier 11A1 (SLC11A1) is a divalent ion transporter formerly known as the natural resistance–associated macrophage protein (NRAMP1) and the Bcg/Lsh/Ity locus. SLC11A1 was thought to be exclusively expressed in monocyte/macrophages and to ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f618f1351c0a9f820af62c9c0724a1
https://doi.org/10.4049/jimmunol.1200732
https://doi.org/10.4049/jimmunol.1200732
Autor:
Hannah M.M. Kerns, Mark A. Jutila, Miranda Radke, Charles Petrie, Emily Kimmel, Pati M. Glee, Larissa Jackiw, Patrick McCurley, Jeff Holderness, Jodi F. Hedges, Aiyappa Palecanda
Publikováno v:
The Journal of Immunology. 179:6468-6478
Gammadelta T cells are innate immune cells that participate in host responses against many pathogens and cancers. Recently, phosphoantigen-based drugs, capable of expanding gammadelta T cells in vivo, entered clinical trials with the goal of enhancin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53038468e9617339cce17b90e3f97ec6
https://doi.org/10.4049/jimmunol.179.10.6468
https://doi.org/10.4049/jimmunol.179.10.6468
Autor:
Pawel Buczek, Mili Shum, Emily Kimmel, Rochelle S. Orr, Shawn E. Gerum, Sean R. Pyper, Martin P. Horvath, Irene Ota
Publikováno v:
Journal of Molecular Biology. 350:938-952
Alpha and beta protein subunits of the telomere end binding protein from Oxytricha nova (OnTEBP) combine with telomere single strand DNA to form a protective cap at the ends of chromosomes. We tested how protein-protein interactions seen in the co-cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72aba5485e55805e96314dfa47e2b3cb
https://doi.org/10.1016/j.jmb.2005.05.040
https://doi.org/10.1016/j.jmb.2005.05.040
Autor:
Andrew Ramstead, Angela M. Mitchell, Deann T. Snyder, Emily Kimmel, Kerri Jones, Mark A. Jutila, Jodi F. Hedges
Publikováno v:
Innate immunity. 21(6)
Amphotericin B (AmB) is a commonly used antifungal drug, with well-documented effects on cellular immune responses. We determined that AmB-stimulated γδ T-cell activation and proliferation in vitro at very low concentrations. AmB also enhanced IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515c206bd96f0aa91821b044886db8ee
https://pubmed.ncbi.nlm.nih.gov/25608515
https://pubmed.ncbi.nlm.nih.gov/25608515
Publikováno v:
The Journal of Immunology. 196:66.17-66.17
SLC11A1 is a divalent ion transporter formerly known as the natural resistance-associated macrophage protein (NRAMP1). Also known as the Bcg/Lsh/Ity locus, SLC11A1 was originally characterized as the resistance factor for Mycobacterium, Leshmania, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5535c7a08e67d1dc235420dbb8b63611
https://doi.org/10.4049/jimmunol.196.supp.66.17
https://doi.org/10.4049/jimmunol.196.supp.66.17
Autor:
Jodi F. Hedges, Maria E. Jerome, Deann T. Snyder, Jeff Holderness, Sharon Kemoli, Mark A. Jutila, Emily Kimmel
Publikováno v:
Antiviral Research
Oligomeric procyanidins (OPCs) have been shown to have antiviral and immunostimulatory effects. OPCs isolated from non-ripe apple peel were tested for capacity to reduce dengue virus (DENV) titers. Similar to published accounts, OPCs exhibited direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368d026fed08bb60e349f7938d61e07d
https://europepmc.org/articles/PMC3076897/
https://europepmc.org/articles/PMC3076897/
Autor:
Emily Kimmel, Brett Freedman, Jodi F. Hedges, Mark A. Jutila, Mark T. Quinn, Igor A. Schepetkin, Jill C. Graff, Jeff Holderness
Publikováno v:
International immunopharmacology. 9(11)
Yamoa (ground bark of Funtumia elastica tree) is marketed and sold as a dietary supplement with anecdotal therapeutic effects in the treatment of asthma and hay fever. We determined that Yamoa and Yamoa-derived polysaccharides affected innate immunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6672d33ad7e75146470cc062d3e6aa76
https://pubmed.ncbi.nlm.nih.gov/19671448
https://pubmed.ncbi.nlm.nih.gov/19671448