Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Emily K. Stroup"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Studies have revealed dozens of functional peptides in putative ‘noncoding’ regions and raised the question of how many proteins are encoded by noncanonical open reading frames (ORFs). Here, we comprehensively annotate genome-wide transl
Externí odkaz:
https://doaj.org/article/6547485e04fc4733913c0b6327b03c26
Autor:
James F. Amatruda, Dinesh Rakheja, Theodore W. Laetsch, Leendert H.J. Looijenga, Lawrence Lum, A. Lindsay Frazier, Payal Kapur, Kiyoshi Yamaguchi, Sarai H. Stuart, Christina Ateek, Albert Budhipramono, Emily K. Stroup, Abhay A. Shukla, Nicholas J. Fustino, Kenneth S. Chen
Germ cell tumors (GCT) are malignant tumors that arise from pluripotent embryonic germ cells and occur in children and young adults. GCTs are treated with cisplatin-based regimens which, while overall effective, fail to cure all patients and cause si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02f346e8bfa5d168d6fbe51a99d23af
https://doi.org/10.1158/1535-7163.c.6538071.v1
https://doi.org/10.1158/1535-7163.c.6538071.v1
Publikováno v:
Current Protocols. 3
Publikováno v:
Genome research. 32(3)
We describe a low-input RNase footprinting approach for the rapid quantification of ribosome-protected fragments with as few as 1000 cultured cells. The assay uses a simplified procedure to selectively capture ribosome footprints based on optimized R
Autor:
Sarai H. Stuart, Veena Rajaram, Kenneth S. Chen, James F. Amatruda, Emily K. Stroup, Gordan M. Vujanic, Tamra Slone, Dinesh Rakheja, Abhay S. Shukla, Jason Wang
Publikováno v:
JCO Precision Oncology. :1-9
DICER1 syndrome1 predisposes to a variety of cancers, including pleuropulmonary blastoma (PPB),2 ovarian Sertoli-Leydig cell tumor (SLCT),3 embryonal rhabdomyosarcoma,4 and kidney tumors.5–8 In DICER1 syndrome, most patients bear a germline null mu
Autor:
Kenneth S, Chen, Sarai H, Stuart, Emily K, Stroup, Abhay S, Shukla, Jason, Wang, Veena, Rajaram, Gordan M, Vujanic, Tamra, Slone, Dinesh, Rakheja, James F, Amatruda
Publikováno v:
JCO precision oncology. 2
Autor:
Claudette Fraire, Abhay A. Shukla, Lin Xu, James F. Amatruda, Sarai H. Stuart, Albert Budhipramono, Kenneth S. Chen, Diana X. Nichols-Vinueza, Emily K. Stroup, Joshua T. Mendell, Dinesh Rakheja
Publikováno v:
Genes & Development. 32:996-1007
Many childhood Wilms tumors are driven by mutations in the microRNA biogenesis machinery, but the mechanism by which these mutations drive tumorigenesis is unknown. Here we show that the transcription factor pleomorphic adenoma gene 1 (PLAG1) is a mi
Autor:
Dinesh Rakheja, Theodore W. Laetsch, Leendert H. J. Looijenga, Emily K. Stroup, Lawrence G. Lum, James F. Amatruda, Abhay A. Shukla, Payal Kapur, Kiyoshi Yamaguchi, A. Lindsay Frazier, Nicholas Fustino, Sarai H. Stuart, Christina S. Ateek, Albert Budhipramono, Kenneth S. Chen
Publikováno v:
Molecular Cancer Therapeutics, 17(5), 1079-1089. American Association for Cancer Research Inc.
Germ cell tumors (GCT) are malignant tumors that arise from pluripotent embryonic germ cells and occur in children and young adults. GCTs are treated with cisplatin-based regimens which, while overall effective, fail to cure all patients and cause si
Autor:
Anat Erdreich-Epstein, Tae Hyun Hwang, Emily K. Stroup, James F. Amatruda, Yunku Yeu, Albert Budhipramono, Kenneth S. Chen, Theodore W. Laetsch, Dinesh Rakheja
Publikováno v:
Cancer Rep (Hoboken)
BACKGROUND: Wilms tumor and rhabdoid tumor can have similar clinical presentations, but they have distinct histological and biological features. For instance, Wilms tumors commonly bear mutations in kidney differentiation or microRNA processing genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5649cbddbb838c827878ae41585fcd27
https://europepmc.org/articles/PMC7941429/
https://europepmc.org/articles/PMC7941429/
Autor:
James F. Amatruda, Yunku Yeu, Anat Erdreich-Epstein, Emily K. Stroup, Albert Budhipramono, Kenneth S. Chen, Theodore W. Laetsch, Dinesh Rakheja, Tae Hyun Hwang
BackgroundRhabdoid tumor is a highly aggressive pediatric cancer characterized by biallelic loss and/or mutation of SMARCB1. Outcomes remain poor, and there are no established ways to target the tumorigenic pathways driven by SMARCB1 inactivation. SM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f10dd51aefcba2b74e99cf67a98842
https://doi.org/10.1101/219709
https://doi.org/10.1101/219709