Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emily K. Mader"'
Publikováno v:
Molecular Therapy. 21(10):1930-1937
Oncolytic viruses are structurally and biologically diverse, spreading through tumors and killing them by various mechanisms and with different kinetics. Here, we created a hybrid vesicular stomatitis/measles virus (VSV/MV) that harnesses the safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6656d00df3d25af66a1e5a50a3171d6
Autor:
Mark J. Federspiel, Stephen J. Russell, Kah-Whye Peng, Emily K. Mader, Angela Dispenzieri, Rae Myers, Greenslade A, Suzanne Greiner
Publikováno v:
Gene Therapy. 20:255-261
Oncolytic viruses can be neutralized in the bloodstream by antiviral antibodies whose titers increase progressively with each exposure, resulting in faster virus inactivation and further reductions in efficacy with each successive dose. A single dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ac36d60f14e1eaccb369c9a38b8924
https://doi.org/10.1038/gt.2012.31
https://doi.org/10.1038/gt.2012.31
Autor:
Greg W. Butler, Mark J. Federspiel, Sean C. Dowdy, Evanthia Galanis, Kah Whye Peng, Allan B. Dietz, Stephen J. Russell, Emily K. Mader, Keith L. Knutson, Andrea Mariani
Publikováno v:
Journal of Translational Medicine, Vol 11, Iss 1, p 20 (2013)
Journal of Translational Medicine
Journal of Translational Medicine
Background Mesenchymal stem cells (MSC) can serve as carriers to deliver oncolytic measles virus (MV) to ovarian tumors. In preparation for a clinical trial to use MSC as MV carriers, we obtained cells from ovarian cancer patients and evaluated feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e140da0505d20541b360c443eb9e12
http://www.translational-medicine.com/content/11/1/20
http://www.translational-medicine.com/content/11/1/20
Autor:
Rae Myers, Glen N. Barber, Nathan Jenks, Jill Thompson, Mark J. Federspiel, Jorge Rakela, Stephen J. Russell, Andrew Greenslade, Suzanne Greiner, Guy E. Griesmann, Stephanie K. Carlson, Thomas R. Meier, Kah Whye Peng, Emily K. Mader, Mitesh J. Borad, Michael C. Blanco, Richard G. Vile
Toxicology studies were performed in rats and rhesus macaques to establish a safe starting dose for intratumoral injection of an oncolytic vesicular stomatitis virus expressing human interferon-beta (VSV-hIFNbeta) in patients with hepatocellular carc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2671e819d4ae0c991928fe1c9704537a
https://europepmc.org/articles/PMC2865219/
https://europepmc.org/articles/PMC2865219/
Autor:
Emily K. Mader, Yoshihiro Maeyama, Allan B. Dietz, Evanthia Galanis, Greg W. Butler, Holly M. Russell, Yi Lin, Kah Whye Peng, Stephen J. Russell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(23)
Purpose: Preexisting antiviral antibodies in cancer patients can quickly neutralize oncolytic measles virus (MV) and decrease its antitumor potency. In contrast to “naked” viruses, cell-associated viruses are protected from antibody neutralizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78a793a6f87d22258c1b078cc14149d
https://pubmed.ncbi.nlm.nih.gov/19934299
https://pubmed.ncbi.nlm.nih.gov/19934299