Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Emily K. Dennis"'
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The recognition of a new yeast, Candida auris, in 2009 in East Asia, and its rapid global spread, was a reminder of the threats posed by multidrug-resistant fungal pathogens. C. auris had likely remained unrecognized for a long time as accurate tests
Externí odkaz:
https://doaj.org/article/d5bc5cbb0b284afb93af4f401dc47178
Autor:
Marina Y. Fosso, Sanjib K. Shrestha, Nishad Thamban Chandrika, Emily K. Dennis, Keith D. Green, Sylvie Garneau-Tsodikova
Publikováno v:
Molecules, Vol 23, Iss 4, p 899 (2018)
As the threat associated with fungal infections continues to rise and the availability of antifungal drugs remains a concern, it becomes obvious that the need to bolster the antifungal armamentarium is urgent. Building from our previous findings of t
Externí odkaz:
https://doaj.org/article/6c42c0598cf84b77ad26df97267804ff
Autor:
Samantha E. Jacobs, Jonathan L. Jacobs, Emily K. Dennis, Sarah Taimur, Meenakshi Rana, Dhruv Patel, Melissa Gitman, Gopi Patel, Sarah Schaefer, Kishore Iyer, Jang Moon, Victoria Adams, Polina Lerner, Thomas J. Walsh, YanChun Zhu, Mohammed Rokebul Anower, Mayuri M. Vaidya, Sudha Chaturvedi, Vishnu Chaturvedi
Publikováno v:
Antimicrob Agents Chemother
Candida auris is an urgent antimicrobial resistance threat due to its global emergence, high mortality, and persistent transmissions. Nearly half of C. auris clinical and surveillance cases in the United States are from the New York and New Jersey Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd47ee8dffc576bdbe607375ecfab09a
https://pubmed.ncbi.nlm.nih.gov/35770999
https://pubmed.ncbi.nlm.nih.gov/35770999
Autor:
Huy X. Ngo, Soo-Kyoung Kim, Vincent T. Lee, Philip DeShong, Nishad Thamban Chandrika, Emily K Dennis, Sylvie Garneau-Tsodikova
Publikováno v:
ACS Infectious Diseases. 7:1713-1726
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that is frequently found in the airways of cystic fibrosis (CF) patients due to the dehydrated mucus that collapses the underlying cilia and prevents mucociliary clearance. During this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd0ff2c8d50c337c3a4ae89287f05fe
https://doi.org/10.1021/acsinfecdis.1c00045
https://doi.org/10.1021/acsinfecdis.1c00045
Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from Mycobacterium tuberculosis
Autor:
Melisa J. Willby, Selina Y. L. Holbrook, Shilah A. Bonnett, Oleg V. Tsodikov, Kyle Krieger, Sylvie Garneau-Tsodikova, James E. Posey, Emily K Dennis, Ankita Punetha, Huy X. Ngo, Keith D. Green, Tanya Parish
Publikováno v:
ACS Chem Biol
The enhanced intracellular survival (Eis) protein of Mycobacterium tuberculosis (Mtb) is a versatile acetyltransferase that multiacetylates aminoglycoside antibiotics abolishing their binding to the bacterial ribosome. When overexpressed as a result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808387ab3f4fd8705c8ab566f038b259
https://doi.org/10.1021/acschembio.0c00184
https://doi.org/10.1021/acschembio.0c00184
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
The recognition of a new yeast, Candida auris, in 2009 in East Asia, and its rapid global spread, was a reminder of the threats posed by multidrug-resistant fungal pathogens. C. auris had likely remained unrecognized for a long time as accurate tests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6fec06d451c845990f157bf314c541
https://doi.org/10.3389/fmicb.2021.757835
https://doi.org/10.3389/fmicb.2021.757835
Autor:
Emily K Dennis, Huy X. Ngo, Linda P. Dwoskin, Sylvie Garneau-Tsodikova, Stefan Kwiatkowski, Nishad Thamban Chandrika, Keith D. Green, Sanjib K. Shrestha, Agripina G. Deaciuc, David S. Watt
Publikováno v:
European Journal of Medicinal Chemistry. 164:273-281
N,N′-Diaryl-bishydrazones of [1,1′-biphenyl]-3,4′-dicarboxaldehyde, [1,1′-biphenyl]-4,4′-dicarboxaldehyde, and 4,4′-bisacetyl-1,1-biphenyl exhibited excellent antifungal activity against a broad spectrum of filamentous and non-filamentous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf1cd03045fd942f86d4932222fd710
https://doi.org/10.1016/j.ejmech.2018.12.042
https://doi.org/10.1016/j.ejmech.2018.12.042
Autor:
Soo-Kyoung, Kim, Huy X, Ngo, Emily K, Dennis, Nishad, Thamban Chandrika, Philip, DeShong, Sylvie, Garneau-Tsodikova, Vincent T, Lee
Publikováno v:
ACS infectious diseases. 7(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1cf41e7f0d19bba1bc3f82584019677
https://pubmed.ncbi.nlm.nih.gov/33871968
https://pubmed.ncbi.nlm.nih.gov/33871968
Autor:
Sylvie Garneau-Tsodikova, Katelyn R. Brubaker, Stefan Kwiatkowski, David S. Watt, Emily K Dennis, Nishad Thamban Chandrika
Publikováno v:
ChemMedChem. 16(1)
Fluorinated aryl- and heteroaryl-substituted monohydrazones displayed excellent broad-spectrum activity against various fungal strains, including a panel of clinically relevant Candida auris strains relative to a control antifungal agent, voriconazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e9b0580aeb42fd2f9a1f77e6490351
https://pubmed.ncbi.nlm.nih.gov/33063957
https://pubmed.ncbi.nlm.nih.gov/33063957
Publikováno v:
RSC Med Chem
Substance use disorders are diseases of the brain that create a dependency on drug(s), either prescription or illicit. These diseases affect millions of people worldwide, yet, there are few treatments that can help patients in the long term. This opi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ec3a3e8bf8185d4a0976d5b4692eb7
https://europepmc.org/articles/PMC7651624/
https://europepmc.org/articles/PMC7651624/
